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The changing epidemiology of dengue in China, 1990-2014: a descriptive analysis of 25 years of nationwide surveillance data

The changing epidemiology of dengue in China, 1990-2014: a descriptive analysis of 25 years of nationwide surveillance data
The changing epidemiology of dengue in China, 1990-2014: a descriptive analysis of 25 years of nationwide surveillance data
BACKGROUND: Dengue has been a notifiable disease in China since 1 September 1989. Cases have been reported each year during the past 25 years of dramatic socio-economic changes in China, and reached a historical high in 2014. This study describes the changing epidemiology of dengue in China during this period, to identify high-risk areas and seasons and to inform dengue prevention and control activities.
METHODS: We describe the incidence and distribution of dengue in mainland China using notifiable surveillance data from 1990-2014, which includes classification of imported and indigenous cases from 2005-2014.
RESULTS: From 1990-2014, 69,321 cases of dengue including 11 deaths were reported in mainland China, equating to 2.2 cases per one million residents. The highest number was recorded in 2014 (47,056 cases). The number of provinces affected has increased, from a median of three provinces per year (range: 1 to 5 provinces) during 1990-2000 to a median of 14.5 provinces per year (range: 5 to 26 provinces) during 2001-2014. During 2005-2014, imported cases were reported almost every month and 28 provinces (90.3%) were affected. However, 99.8% of indigenous cases occurred between July and November. The regions reporting indigenous cases have expanded from the coastal provinces of southern China and provinces adjacent to Southeast Asia to the central part of China. Dengue virus serotypes 1, 2, 3, and 4 were all detected from 2009-2014.
CONCLUSIONS: In China, the area affected by dengue has expanded since 2000 and the incidence has increased steadily since 2012, for both imported and indigenous dengue. Surveillance and control strategies should be adjusted to account for these changes, and further research should explore the drivers of these trends. Please see related article: http://dx.doi.org/10.1186/s12916-015-0345-0.
1-12
Lai, Shengjie
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Huang, Zhuojie
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Zhou, Hang
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Anders, Katherine L.
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Perkins, T. Alex
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Yin, Wenwu
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Li, Yu
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Mu, Di
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Chen, Qiulan
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Zhang, Zike
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Qiu, Yanzi
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Wang, Liping
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Zhang, Honglong
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Zeng, Linjia
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Ren, Xiang
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Geng, Mengjie
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Li, Zhongjie
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Tatem, Andrew J.
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Hay, Simon I.
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Yu, Hongjie
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Lai, Shengjie
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Huang, Zhuojie
07e288b7-51b3-414a-82b7-28d83b114be6
Zhou, Hang
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Anders, Katherine L.
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Perkins, T. Alex
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Yin, Wenwu
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Li, Yu
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Mu, Di
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Chen, Qiulan
ba6f6420-7bdd-4650-b34d-b5e084baff96
Zhang, Zike
85c05276-59dd-4033-82c9-4d33e872906b
Qiu, Yanzi
0177337d-54bb-4fdc-a411-b2ff6e04ff84
Wang, Liping
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Zhang, Honglong
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Zeng, Linjia
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Ren, Xiang
79e57eaa-a085-47b3-a8b3-274840938696
Geng, Mengjie
e6f1eb5b-86e9-4ac4-89ae-a9ec3b6df56f
Li, Zhongjie
f89a98f7-f6d3-4312-995a-bc658ae9a93f
Tatem, Andrew J.
cac5d599-ac59-4a77-8dd9-b39f8428fdcb
Hay, Simon I.
471d3ae4-a3c1-4d29-93e3-a90d44471b00
Yu, Hongjie
f6a43c0c-0da8-4124-bd15-cd832d6fee7c

Lai, Shengjie, Huang, Zhuojie, Zhou, Hang, Anders, Katherine L., Perkins, T. Alex, Yin, Wenwu, Li, Yu, Mu, Di, Chen, Qiulan, Zhang, Zike, Qiu, Yanzi, Wang, Liping, Zhang, Honglong, Zeng, Linjia, Ren, Xiang, Geng, Mengjie, Li, Zhongjie, Tatem, Andrew J., Hay, Simon I. and Yu, Hongjie (2015) The changing epidemiology of dengue in China, 1990-2014: a descriptive analysis of 25 years of nationwide surveillance data. BMC Medicine, 13, 1-12, [100]. (doi:10.1186/s12916-015-0336-1).

Record type: Article

Abstract

BACKGROUND: Dengue has been a notifiable disease in China since 1 September 1989. Cases have been reported each year during the past 25 years of dramatic socio-economic changes in China, and reached a historical high in 2014. This study describes the changing epidemiology of dengue in China during this period, to identify high-risk areas and seasons and to inform dengue prevention and control activities.
METHODS: We describe the incidence and distribution of dengue in mainland China using notifiable surveillance data from 1990-2014, which includes classification of imported and indigenous cases from 2005-2014.
RESULTS: From 1990-2014, 69,321 cases of dengue including 11 deaths were reported in mainland China, equating to 2.2 cases per one million residents. The highest number was recorded in 2014 (47,056 cases). The number of provinces affected has increased, from a median of three provinces per year (range: 1 to 5 provinces) during 1990-2000 to a median of 14.5 provinces per year (range: 5 to 26 provinces) during 2001-2014. During 2005-2014, imported cases were reported almost every month and 28 provinces (90.3%) were affected. However, 99.8% of indigenous cases occurred between July and November. The regions reporting indigenous cases have expanded from the coastal provinces of southern China and provinces adjacent to Southeast Asia to the central part of China. Dengue virus serotypes 1, 2, 3, and 4 were all detected from 2009-2014.
CONCLUSIONS: In China, the area affected by dengue has expanded since 2000 and the incidence has increased steadily since 2012, for both imported and indigenous dengue. Surveillance and control strategies should be adjusted to account for these changes, and further research should explore the drivers of these trends. Please see related article: http://dx.doi.org/10.1186/s12916-015-0345-0.

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Accepted/In Press date: 24 March 2015
e-pub ahead of print date: 28 April 2015
Published date: 28 April 2015
Organisations: Global Env Change & Earth Observation, WorldPop, Geography & Environment, Population, Health & Wellbeing (PHeW)

Identifiers

Local EPrints ID: 376615
URI: http://eprints.soton.ac.uk/id/eprint/376615
PURE UUID: 741b8121-d2dd-4b97-b88e-6415c279f234
ORCID for Shengjie Lai: ORCID iD orcid.org/0000-0001-9781-8148

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Date deposited: 05 May 2015 16:09
Last modified: 15 Mar 2024 04:02

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Contributors

Author: Shengjie Lai ORCID iD
Author: Zhuojie Huang
Author: Hang Zhou
Author: Katherine L. Anders
Author: T. Alex Perkins
Author: Wenwu Yin
Author: Yu Li
Author: Di Mu
Author: Qiulan Chen
Author: Zike Zhang
Author: Yanzi Qiu
Author: Liping Wang
Author: Honglong Zhang
Author: Linjia Zeng
Author: Xiang Ren
Author: Mengjie Geng
Author: Zhongjie Li
Author: Andrew J. Tatem
Author: Simon I. Hay
Author: Hongjie Yu

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