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Psychosis in a cocaine-dependent patient with ADHD during treatment with methylphenidate

Psychosis in a cocaine-dependent patient with ADHD during treatment with methylphenidate
Psychosis in a cocaine-dependent patient with ADHD during treatment with methylphenidate
Objective
The objective was to report a case of experienced psychosis during the treatment with methylphenidate (MPH) in a cocaine-dependent adult treated for attention-deficit/hyperactivity disorder (ADHD) with comorbid cocaine dependence.

Conclusion
ADHD is a frequent comorbidity in substance use disorder (SUD) patients. MPH may be effective in treating ADHD symptoms in SUD patients, thus preventing possible adverse outcomes. Cocaine-induced psychosis may be a risk factor for development of psychosis in the presence of a concurrent treatment with MPH.
psychosis-induced, ADHD, cocaine, substance use disorder, methylphenidate, adverse effect, dopamine
0163-8343
451.e7-451.e9
Delavenne, Héloïse
3c4bd606-d542-450f-ad68-3c464fc07aa6
Duarte Garcia, Frederico
34cc6050-f3de-4aab-a3b2-ca42fb58939c
Lacoste, Jérôme
60de9a75-40cb-4708-8766-915dddf5715a
Cortese, Samuele
53d4bf2c-4e0e-4c77-9385-218350560fdb
Charles-Nicolas, Aimé
50482400-550f-411f-99db-45aa31efbc73
Ballon, Nicolas
8bf65013-2ad3-438c-a51a-007e24e786c4
Delavenne, Héloïse
3c4bd606-d542-450f-ad68-3c464fc07aa6
Duarte Garcia, Frederico
34cc6050-f3de-4aab-a3b2-ca42fb58939c
Lacoste, Jérôme
60de9a75-40cb-4708-8766-915dddf5715a
Cortese, Samuele
53d4bf2c-4e0e-4c77-9385-218350560fdb
Charles-Nicolas, Aimé
50482400-550f-411f-99db-45aa31efbc73
Ballon, Nicolas
8bf65013-2ad3-438c-a51a-007e24e786c4

Delavenne, Héloïse, Duarte Garcia, Frederico, Lacoste, Jérôme, Cortese, Samuele, Charles-Nicolas, Aimé and Ballon, Nicolas (2013) Psychosis in a cocaine-dependent patient with ADHD during treatment with methylphenidate. General Hospital Psychiatry, 35 (4), 451.e7-451.e9. (doi:10.1016/j.genhosppsych.2012.05.010).

Record type: Article

Abstract

Objective
The objective was to report a case of experienced psychosis during the treatment with methylphenidate (MPH) in a cocaine-dependent adult treated for attention-deficit/hyperactivity disorder (ADHD) with comorbid cocaine dependence.

Conclusion
ADHD is a frequent comorbidity in substance use disorder (SUD) patients. MPH may be effective in treating ADHD symptoms in SUD patients, thus preventing possible adverse outcomes. Cocaine-induced psychosis may be a risk factor for development of psychosis in the presence of a concurrent treatment with MPH.

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More information

Accepted/In Press date: 29 May 2012
e-pub ahead of print date: 25 June 2012
Published date: July 2013
Keywords: psychosis-induced, ADHD, cocaine, substance use disorder, methylphenidate, adverse effect, dopamine
Organisations: Clinical Neuroscience

Identifiers

Local EPrints ID: 380185
URI: http://eprints.soton.ac.uk/id/eprint/380185
ISSN: 0163-8343
PURE UUID: 4c1714bb-a606-4593-87b5-c950807a88a9
ORCID for Samuele Cortese: ORCID iD orcid.org/0000-0001-5877-8075

Catalogue record

Date deposited: 21 Aug 2015 12:39
Last modified: 15 Mar 2024 03:52

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Contributors

Author: Héloïse Delavenne
Author: Frederico Duarte Garcia
Author: Jérôme Lacoste
Author: Samuele Cortese ORCID iD
Author: Aimé Charles-Nicolas
Author: Nicolas Ballon

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