Practitioner Review: Current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents
Practitioner Review: Current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents
Background:? Medication is an important element of therapeutic strategies for ADHD. While medications for ADHD are generally well-tolerated, there are common, although less severe, as well as rare but severe adverse events AEs during treatment with ADHD drugs. The aim of this review is to provide evidence- and expert-based guidance concerning the management of (AEs) with medications for ADHD.
Methods:? For ease of use by practitioners and clinicians, the article is organized in a simple question and answer format regarding the prevalence and management of the most common AEs. Answers were based on empirical evidence from studies (preferably meta-analyses or systematic reviews) retrieved in PubMed, Ovid, EMBASE and Web of Knowledge through 30 June 2012. When no empirical evidence was available, expert consensus of the members of the European ADHD Guidelines Group is provided. The evidence-level of the management recommendations was based on the SIGN grading system.
Results:? The review covers monitoring and management strategies of loss of appetite and growth delay, cardiovascular risks, sleep disturbance, tics, substance misuse/abuse, seizures, suicidal thoughts/behaviours and psychotic symptoms.
Conclusion:? Most AEs during treatment with drugs for ADHD are manageable and most of the times it is not necessary to stop medication, so that patients with ADHD may continue to benefit from the effectiveness of pharmacological treatment.
ADHD, medication, adverse events, management, recommendations, European
227-246
Cortese, Samuele
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Holtmann, Martin
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Banaschewski, Tobias
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Buitelaar, Jan
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Coghill, David
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Danckaerts, Marina
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Dittmann, Ralf W.
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Graham, John
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Taylor, Eric
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Sergeant, Joseph
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7 January 2013
Cortese, Samuele
53d4bf2c-4e0e-4c77-9385-218350560fdb
Holtmann, Martin
511fa11b-f2cb-413f-880e-50c3b04ad9d3
Banaschewski, Tobias
4627c589-04cc-4f5b-ac2d-05f547f63dfd
Buitelaar, Jan
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Coghill, David
deea8957-fdfc-488a-a3bb-fb9b536c7172
Danckaerts, Marina
e7e7618b-6dd0-4520-bf4e-865597928758
Dittmann, Ralf W.
e2d36a60-d6c5-485d-8ce5-852d5a1b9bfd
Graham, John
ff2b82fa-513c-4965-ad77-a38bb0251752
Taylor, Eric
0df56dc7-9553-44e2-9594-612d758f8684
Sergeant, Joseph
9d13c879-0b3b-45df-8ba7-3978ca029ac5
Cortese, Samuele, Holtmann, Martin, Banaschewski, Tobias, Buitelaar, Jan, Coghill, David, Danckaerts, Marina, Dittmann, Ralf W., Graham, John, Taylor, Eric and Sergeant, Joseph
(2013)
Practitioner Review: Current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents.
Journal of Child Psychology and Psychiatry, 54 (3), .
(doi:10.1111/jcpp.12036).
Abstract
Background:? Medication is an important element of therapeutic strategies for ADHD. While medications for ADHD are generally well-tolerated, there are common, although less severe, as well as rare but severe adverse events AEs during treatment with ADHD drugs. The aim of this review is to provide evidence- and expert-based guidance concerning the management of (AEs) with medications for ADHD.
Methods:? For ease of use by practitioners and clinicians, the article is organized in a simple question and answer format regarding the prevalence and management of the most common AEs. Answers were based on empirical evidence from studies (preferably meta-analyses or systematic reviews) retrieved in PubMed, Ovid, EMBASE and Web of Knowledge through 30 June 2012. When no empirical evidence was available, expert consensus of the members of the European ADHD Guidelines Group is provided. The evidence-level of the management recommendations was based on the SIGN grading system.
Results:? The review covers monitoring and management strategies of loss of appetite and growth delay, cardiovascular risks, sleep disturbance, tics, substance misuse/abuse, seizures, suicidal thoughts/behaviours and psychotic symptoms.
Conclusion:? Most AEs during treatment with drugs for ADHD are manageable and most of the times it is not necessary to stop medication, so that patients with ADHD may continue to benefit from the effectiveness of pharmacological treatment.
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More information
Published date: 7 January 2013
Keywords:
ADHD, medication, adverse events, management, recommendations, European
Organisations:
Clinical Neuroscience
Identifiers
Local EPrints ID: 380191
URI: http://eprints.soton.ac.uk/id/eprint/380191
ISSN: 0021-9630
PURE UUID: b1295d49-3b82-4cf3-bae1-3e972f95148d
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Date deposited: 20 Aug 2015 15:42
Last modified: 15 Mar 2024 03:52
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Contributors
Author:
Martin Holtmann
Author:
Tobias Banaschewski
Author:
Jan Buitelaar
Author:
David Coghill
Author:
Marina Danckaerts
Author:
Ralf W. Dittmann
Author:
John Graham
Author:
Eric Taylor
Author:
Joseph Sergeant
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