ZnO nanowire-FET for charge-based sensing of protein molecules
ZnO nanowire-FET for charge-based sensing of protein molecules
Top-down method was used to fabricate zinc oxide (ZnO) nano wire field effect transistor (NWFET) biosensor. The nanosensor was used to measure the electrical characteristics of lysozyme (LYSO) and bovine serum albumin (BSA) protein solutions in phosphate buffered saline (PBS). The LYSO and BSA proteins are oppositely charged at measurement pH of 7.4. Subthreshold voltage shift of 340 mV and 700 mV due to surface charge effect on the device channel is obtained for the LYSO and BSA solutions respectively. A NWFET sensitivity of 72 % is achieved for the LYSO proteins while the BSA proteins resulted in a sensitivity of 98%.
801-804
Ditshego, N.M.J.
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Ghazali, N.A.B.
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Ebert, M.
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Sun, K.
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Zeimpekis, I.
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Ashburn, P.
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De Planque, M.R.R.
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Chong, H.M.H.
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Ditshego, N.M.J.
12e0ccd8-8b73-47bd-a896-07d0268fb769
Ghazali, N.A.B.
95cd0479-dcb4-485c-8de5-009e4f02371f
Ebert, M.
f412aa6c-50da-4d94-b56e-a0e718d1cb1e
Sun, K.
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Zeimpekis, I.
a2c354ec-3891-497c-adac-89b3a5d96af0
Ashburn, P.
68cef6b7-205b-47aa-9efb-f1f09f5c1038
De Planque, M.R.R.
a1d33d13-f516-44fb-8d2c-c51d18bc21ba
Chong, H.M.H.
795aa67f-29e5-480f-b1bc-9bd5c0d558e1
Ditshego, N.M.J., Ghazali, N.A.B., Ebert, M., Sun, K., Zeimpekis, I., Ashburn, P., De Planque, M.R.R. and Chong, H.M.H.
(2016)
ZnO nanowire-FET for charge-based sensing of protein molecules.
In 2015 IEEE 15th International Conference on Nanotechnology (IEEE-NANO).
IEEE.
.
(doi:10.1109/NANO.2015.7388733).
Record type:
Conference or Workshop Item
(Paper)
Abstract
Top-down method was used to fabricate zinc oxide (ZnO) nano wire field effect transistor (NWFET) biosensor. The nanosensor was used to measure the electrical characteristics of lysozyme (LYSO) and bovine serum albumin (BSA) protein solutions in phosphate buffered saline (PBS). The LYSO and BSA proteins are oppositely charged at measurement pH of 7.4. Subthreshold voltage shift of 340 mV and 700 mV due to surface charge effect on the device channel is obtained for the LYSO and BSA solutions respectively. A NWFET sensitivity of 72 % is achieved for the LYSO proteins while the BSA proteins resulted in a sensitivity of 98%.
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e-pub ahead of print date: 21 January 2016
Venue - Dates:
2015 IEEE 15th International Conference on Nanotechnology, , Rome, Italy, 2015-07-27 - 2015-07-30
Organisations:
Nanoelectronics and Nanotechnology
Identifiers
Local EPrints ID: 380735
URI: http://eprints.soton.ac.uk/id/eprint/380735
PURE UUID: cec560e5-adfd-4a63-8a21-284a4f2f4cba
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Date deposited: 19 Aug 2015 11:42
Last modified: 18 Mar 2024 03:18
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Contributors
Author:
N.M.J. Ditshego
Author:
N.A.B. Ghazali
Author:
M. Ebert
Author:
M.R.R. De Planque
Author:
H.M.H. Chong
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