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Energy content of stools in normal healthy controls and patients with cystic fibrosis

Energy content of stools in normal healthy controls and patients with cystic fibrosis
Energy content of stools in normal healthy controls and patients with cystic fibrosis
Stool energy losses and the sources of energy within the stool were determined in 20 healthy controls and 20 patients with cystic fibrosis while on their habitual pancreatic enzyme replacement treatment. Stool energy losses were equivalent to 3.5% of gross energy intake in healthy children (range 1.3-5.8%). Despite a comparable gross energy intake, stool energy losses were three times greater in patients with cystic fibrosis than controls averaging 10.6% of gross energy intake (range 4.9-19.7%). Stool lipid could account for only 29% and 41% of the energy within the stool in controls and patients with cystic fibrosis respectively and was poorly related to stool energy. Approximately 30% of the energy within the stool could be attributable to colonic bacteria in both the healthy children and patients with cystic fibrosis. These results suggest that stool energy losses in healthy children are relatively modest but that even when patients with cystic fibrosis are symptomatically well controlled on pancreatic enzyme replacement, raised stool energy losses may continue to contribute towards an energy deficit sufficient to limit growth in cystic fibrosis. As the energy content per gram wet weight remains relatively constant (8 kJ/g), stool energy losses may be estimated from simple measurements of stool wet weight.
0003-9888
495-500
Murphy, J.L.
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Wootton, S.A.
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Bond, S.A.
2db07b98-3d10-4fa4-a6d2-bb24c387bc35
Jackson, A.A.
c9a12d7c-b4d6-4c92-820e-890a688379ef
Murphy, J.L.
99e7863d-f870-438a-b4f5-bec8a2e78ebd
Wootton, S.A.
bf47ef35-0b33-4edb-a2b0-ceda5c475c0c
Bond, S.A.
2db07b98-3d10-4fa4-a6d2-bb24c387bc35
Jackson, A.A.
c9a12d7c-b4d6-4c92-820e-890a688379ef

Murphy, J.L., Wootton, S.A., Bond, S.A. and Jackson, A.A. (1991) Energy content of stools in normal healthy controls and patients with cystic fibrosis. Archives of Disease in Childhood, 66 (4), 495-500. (PMID:7148760)

Record type: Article

Abstract

Stool energy losses and the sources of energy within the stool were determined in 20 healthy controls and 20 patients with cystic fibrosis while on their habitual pancreatic enzyme replacement treatment. Stool energy losses were equivalent to 3.5% of gross energy intake in healthy children (range 1.3-5.8%). Despite a comparable gross energy intake, stool energy losses were three times greater in patients with cystic fibrosis than controls averaging 10.6% of gross energy intake (range 4.9-19.7%). Stool lipid could account for only 29% and 41% of the energy within the stool in controls and patients with cystic fibrosis respectively and was poorly related to stool energy. Approximately 30% of the energy within the stool could be attributable to colonic bacteria in both the healthy children and patients with cystic fibrosis. These results suggest that stool energy losses in healthy children are relatively modest but that even when patients with cystic fibrosis are symptomatically well controlled on pancreatic enzyme replacement, raised stool energy losses may continue to contribute towards an energy deficit sufficient to limit growth in cystic fibrosis. As the energy content per gram wet weight remains relatively constant (8 kJ/g), stool energy losses may be estimated from simple measurements of stool wet weight.

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More information

Published date: April 1991
Organisations: Human Development & Health

Identifiers

Local EPrints ID: 383856
URI: http://eprints.soton.ac.uk/id/eprint/383856
ISSN: 0003-9888
PURE UUID: eec5f8d7-e174-463d-994a-e9aa6cfc463c

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Date deposited: 26 Nov 2015 13:57
Last modified: 11 Dec 2021 08:05

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Contributors

Author: J.L. Murphy
Author: S.A. Wootton
Author: S.A. Bond
Author: A.A. Jackson

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