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Proteomic approaches to dissect neuronal signaling pathways

Proteomic approaches to dissect neuronal signaling pathways
Proteomic approaches to dissect neuronal signaling pathways
With an increasing awareness of mental health issues and neurological disorders, "understanding the brain" is one of the biggest current challenges in biological research. This has been recognized by both governments and funding agencies, and includes the need to understand connectivity of brain regions and coordinated network activity, as well as cellular and molecular mechanisms at play. In this chapter, we will describe how we have taken advantage of different proteomic techniques to unravel molecular mechanisms underlying two modulators of neuronal function: Neurotrophins and antipsychotics.
0065-2598
499-508
Bowling, Heather L.
38bc7a9f-32fe-4cd7-9a47-9fb1a23507be
Deinhardt, Katrin
5f4fe23b-2317-499f-ba6d-e639a4885dc1
Bowling, Heather L.
38bc7a9f-32fe-4cd7-9a47-9fb1a23507be
Deinhardt, Katrin
5f4fe23b-2317-499f-ba6d-e639a4885dc1

Bowling, Heather L. and Deinhardt, Katrin (2014) Proteomic approaches to dissect neuronal signaling pathways. Advances in Experimental Medicine and Biology, 806, 499-508. (doi:10.1007/978-3-319-06068-2_24). (PMID:24952199)

Record type: Article

Abstract

With an increasing awareness of mental health issues and neurological disorders, "understanding the brain" is one of the biggest current challenges in biological research. This has been recognized by both governments and funding agencies, and includes the need to understand connectivity of brain regions and coordinated network activity, as well as cellular and molecular mechanisms at play. In this chapter, we will describe how we have taken advantage of different proteomic techniques to unravel molecular mechanisms underlying two modulators of neuronal function: Neurotrophins and antipsychotics.

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Published date: 19 May 2014
Organisations: Biomedicine

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Local EPrints ID: 385134
URI: http://eprints.soton.ac.uk/id/eprint/385134
ISSN: 0065-2598
PURE UUID: f30d2ac2-eab3-42eb-8af1-b02905a1b2db
ORCID for Katrin Deinhardt: ORCID iD orcid.org/0000-0002-6473-5298

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Date deposited: 15 Jan 2016 15:24
Last modified: 15 Mar 2024 03:45

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Contributors

Author: Heather L. Bowling

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