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Laser direct-write for fabrication of three-dimensional paper-based devices

Laser direct-write for fabrication of three-dimensional paper-based devices
Laser direct-write for fabrication of three-dimensional paper-based devices
We report the use of a laser-based direct-write (LDW) technique that allows the design and fabrication of three-dimensional (3D) structures within a paper substrate that enables implementation of multi-step analytical assays via a 3D protocol. The technique is based on laser-induced photo-polymerisation, and through adjustment of the laser writing parameters such as the laser power and scan speed we can control the depths of hydrophobic barriers that are formed within a substrate which, when carefully designed and integrated, produce 3D flow paths. So far, we have successfully used this depth-variable patterning protocol for stacking and sealing of multi-layer substrates, for assembly of backing layers for two-dimensional (2D) lateral flow devices and finally for fabrication of 3D devices. Since the 3D flow paths can also be formed via a single laser-writing process by controlling the patterning parameters, this is a distinct improvement over other methods that require multiple complicated and repetitive assembly procedures. This technique is therefore suitable for cheap, rapid and large-scale fabrication of 3D paper-based microfluidic devices.
University of Southampton
He, Peijun
6faacea8-db2e-4bab-8198-3aa595724794
Katis, Ioannis
f92dfb8f-610d-4877-83f6-fd26a571df12
Eason, Robert
e38684c3-d18c-41b9-a4aa-def67283b020
Sones, Collin
9de9d8ee-d394-46a5-80b7-e341c0eed0a8
He, Peijun
6faacea8-db2e-4bab-8198-3aa595724794
Katis, Ioannis
f92dfb8f-610d-4877-83f6-fd26a571df12
Eason, Robert
e38684c3-d18c-41b9-a4aa-def67283b020
Sones, Collin
9de9d8ee-d394-46a5-80b7-e341c0eed0a8

He, Peijun, Katis, Ioannis, Eason, Robert and Sones, Collin (2016) Laser direct-write for fabrication of three-dimensional paper-based devices. University of Southampton doi:10.5258/SOTON/387247 [Dataset]

Record type: Dataset

Abstract

We report the use of a laser-based direct-write (LDW) technique that allows the design and fabrication of three-dimensional (3D) structures within a paper substrate that enables implementation of multi-step analytical assays via a 3D protocol. The technique is based on laser-induced photo-polymerisation, and through adjustment of the laser writing parameters such as the laser power and scan speed we can control the depths of hydrophobic barriers that are formed within a substrate which, when carefully designed and integrated, produce 3D flow paths. So far, we have successfully used this depth-variable patterning protocol for stacking and sealing of multi-layer substrates, for assembly of backing layers for two-dimensional (2D) lateral flow devices and finally for fabrication of 3D devices. Since the 3D flow paths can also be formed via a single laser-writing process by controlling the patterning parameters, this is a distinct improvement over other methods that require multiple complicated and repetitive assembly procedures. This technique is therefore suitable for cheap, rapid and large-scale fabrication of 3D paper-based microfluidic devices.

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Volume_20sensitivity.xlsx - Dataset
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More information

Published date: 2016
Organisations: Optoelectronics Research Centre, ORC Research, Faculty of Physical Sciences and Engineering
Projects:
Integrated Photonic Materials and Devices
Funded by: UNSPECIFIED (EP/J008052/1)
1 March 2012 to 29 February 2016
Laser-printable point-of-care sensors for low-cost medical diagnosis and disease monitoring
Funded by: UNSPECIFIED (EP/K023454/1)
1 May 2013 to 31 October 2014
Laser-based engineering of paper for manufacturing fluidic sensors: (Lab-flo)
Funded by: UNSPECIFIED (EP/N004388/1)
7 October 2015 to 6 October 2018

Identifiers

Local EPrints ID: 387247
URI: http://eprints.soton.ac.uk/id/eprint/387247
PURE UUID: 1a6f379e-3ec3-4afd-8135-5e88959f97e5
ORCID for Ioannis Katis: ORCID iD orcid.org/0000-0002-2016-557X
ORCID for Robert Eason: ORCID iD orcid.org/0000-0001-9704-2204

Catalogue record

Date deposited: 06 Oct 2016 15:57
Last modified: 05 Nov 2023 02:48

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Contributors

Creator: Peijun He
Creator: Ioannis Katis ORCID iD
Creator: Robert Eason ORCID iD
Creator: Collin Sones

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