The immune response in HPV(+) oropharyngeal cancer
The immune response in HPV(+) oropharyngeal cancer
Although human papillomavirus (HPV)(+) oropharyngeal cancers often present with metastasis, most patients have excellent long-term survival. The reason underlying such an apparent contradiction remains unclear, but we have recently demonstrated that the improved survival of HPV(+) oropharyngeal cancer patients has an immunological component, as the levels of tumor-infiltrating lymphocytes (TILs) can be used to stratify HPV(+) patients into high-risk and low-risk groups.
King, Emma V.
d85e0e8f-7295-4912-9052-646a790d99db
Ottensmeier, Christian H.
42b8a398-baac-4843-a3d6-056225675797
Thomas, Gareth J.
2ff54aa9-a766-416b-91ee-cf1c5be74106
1 January 2014
King, Emma V.
d85e0e8f-7295-4912-9052-646a790d99db
Ottensmeier, Christian H.
42b8a398-baac-4843-a3d6-056225675797
Thomas, Gareth J.
2ff54aa9-a766-416b-91ee-cf1c5be74106
King, Emma V., Ottensmeier, Christian H. and Thomas, Gareth J.
(2014)
The immune response in HPV(+) oropharyngeal cancer.
OncoImmunology, 3 (1), [e27254].
(doi:10.4161/onci.27254).
(PMID:24575385)
Abstract
Although human papillomavirus (HPV)(+) oropharyngeal cancers often present with metastasis, most patients have excellent long-term survival. The reason underlying such an apparent contradiction remains unclear, but we have recently demonstrated that the improved survival of HPV(+) oropharyngeal cancer patients has an immunological component, as the levels of tumor-infiltrating lymphocytes (TILs) can be used to stratify HPV(+) patients into high-risk and low-risk groups.
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2014 The immune response in HPV oropharyngeal cancer.pdf
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Accepted/In Press date: 18 November 2013
e-pub ahead of print date: 1 January 2014
Published date: 1 January 2014
Organisations:
Cancer Sciences
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Local EPrints ID: 395566
URI: http://eprints.soton.ac.uk/id/eprint/395566
ISSN: 2162-402X
PURE UUID: 99136a7b-7fa9-424f-91c5-0428b013aa44
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Date deposited: 01 Jun 2016 13:18
Last modified: 15 Mar 2024 00:43
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