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Lymphopenia in treatment-naive relapsing multiple sclerosis

Lymphopenia in treatment-naive relapsing multiple sclerosis
Lymphopenia in treatment-naive relapsing multiple sclerosis
Lymphopenia accompanies some autoimmune diseases. A number of studies, but not others, have suggested that lymphopenia occurs in treatment-naive multiple sclerosis (MS), so the issue remains unresolved. This is important since lymphopenia may identify an immunologically distinct subset of MS. Also, lymphopenia may emerge as a risk factor for serious viral infections of the brain during dimethyl fumarate treatment. We therefore embarked on a retrospective controlled study of pre-treatment lymphopenia in relapsing MS
2332-7812
Lim, Zhi Wei
c55e5411-4259-4ee4-a6fb-4adcc16c6e2a
Elwood, Elliot
782a9903-2086-42d2-b406-205f7d8fae56
Naveed, Hammad
35ae4cf9-81c3-47a4-bb6d-32461a41aca6
Galea, Ian
66209a2f-f7e6-4d63-afe4-e9299f156f0b
Lim, Zhi Wei
c55e5411-4259-4ee4-a6fb-4adcc16c6e2a
Elwood, Elliot
782a9903-2086-42d2-b406-205f7d8fae56
Naveed, Hammad
35ae4cf9-81c3-47a4-bb6d-32461a41aca6
Galea, Ian
66209a2f-f7e6-4d63-afe4-e9299f156f0b

Lim, Zhi Wei, Elwood, Elliot, Naveed, Hammad and Galea, Ian (2016) Lymphopenia in treatment-naive relapsing multiple sclerosis. Neurology: Neuroimmunology & Neuroinflammation, 3 (5), [e275]. (doi:10.1212/NXI.0000000000000275).

Record type: Article

Abstract

Lymphopenia accompanies some autoimmune diseases. A number of studies, but not others, have suggested that lymphopenia occurs in treatment-naive multiple sclerosis (MS), so the issue remains unresolved. This is important since lymphopenia may identify an immunologically distinct subset of MS. Also, lymphopenia may emerge as a risk factor for serious viral infections of the brain during dimethyl fumarate treatment. We therefore embarked on a retrospective controlled study of pre-treatment lymphopenia in relapsing MS

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More information

Accepted/In Press date: 11 July 2016
e-pub ahead of print date: 12 August 2016
Published date: October 2016
Organisations: Clinical & Experimental Sciences

Identifiers

Local EPrints ID: 398077
URI: http://eprints.soton.ac.uk/id/eprint/398077
ISSN: 2332-7812
PURE UUID: 082977eb-8edf-4a36-b176-7234a0df83f7
ORCID for Ian Galea: ORCID iD orcid.org/0000-0002-1268-5102

Catalogue record

Date deposited: 18 Jul 2016 08:33
Last modified: 15 Mar 2024 03:16

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Contributors

Author: Zhi Wei Lim
Author: Elliot Elwood
Author: Hammad Naveed
Author: Ian Galea ORCID iD

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