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Cost-effective faster wound healing with a sustained silver-releasing foam dressing in delayed healing leg ulcers - a health-economic analysis

Cost-effective faster wound healing with a sustained silver-releasing foam dressing in delayed healing leg ulcers - a health-economic analysis
Cost-effective faster wound healing with a sustained silver-releasing foam dressing in delayed healing leg ulcers - a health-economic analysis
The aim of this analysis was to examine the cost-effectiveness of Contreet Foam (A) in comparison with three other commonly used venous leg ulcer treatment protocols: Aquacel Ag (B), Actisorb Silver (C) and Iodoflex (D). A health-economic analysis reflecting the UK treatment practice and cost structure was performed. The analysis was set up to assess the cost of relative wound area reduction over a 4-week treatment period. The model was validated by a UK expert panel consisting of four wound care specialists. To assure that the 4-week model had a realistic link to cost-effectiveness of complete wound healing, a Markov analysis was also performed. Sensitivity analyses were carried out to ensure validity. Protocol A and C proved to be the most effective treatments. The mean relative reduction in wound area after 4 weeks of treatment was 50·2% (protocol A), 23·9% (protocol B), 44·6% (protocol C) and 36·0% (protocol D). Cost-effectiveness ratios showed that protocol A proved to be the most cost-effective treatment, and protocol B the least. The cost per percentage reduction in wound area was £9·50 for protocol A, compared to £16·50–17·60 for the other treatment options. The cost-effectiveness of complete healing (Markov analysis) and sensitivity analyses confirmed these results. Using Contreet Foam instead of the other dressing alternatives may imply savings of £2·2–4·4 million per year to the National Health Service.
cost-effectiveness, contreet foam, silver, venous leg ulcer, antimicrobial treatment
1742-4801
150-160
Scanlon, Elizabeth
04af9e3f-43e6-4865-8e48-fbde529b0f75
Karlsmark, Tonny
6f35e900-176c-4ee7-b8d9-417243e0e06d
Leaper, David J.
de467550-ab56-4a7b-ba85-387b5cd5b9fd
Carter, Kate
7d92b21c-68a0-484f-92bc-062ada65411c
Poulsen, Peter B.
464b9b1d-2c23-460e-9ed2-06939c33fc65
Hart-Hansen, Kristian
d56a1279-c6cc-4db7-8ea4-741ad410cb3e
Hahn, Tina W.
1bd6d73d-9c1f-41c3-8a73-6a4bf58fec42
Scanlon, Elizabeth
04af9e3f-43e6-4865-8e48-fbde529b0f75
Karlsmark, Tonny
6f35e900-176c-4ee7-b8d9-417243e0e06d
Leaper, David J.
de467550-ab56-4a7b-ba85-387b5cd5b9fd
Carter, Kate
7d92b21c-68a0-484f-92bc-062ada65411c
Poulsen, Peter B.
464b9b1d-2c23-460e-9ed2-06939c33fc65
Hart-Hansen, Kristian
d56a1279-c6cc-4db7-8ea4-741ad410cb3e
Hahn, Tina W.
1bd6d73d-9c1f-41c3-8a73-6a4bf58fec42

Scanlon, Elizabeth, Karlsmark, Tonny, Leaper, David J., Carter, Kate, Poulsen, Peter B., Hart-Hansen, Kristian and Hahn, Tina W. (2005) Cost-effective faster wound healing with a sustained silver-releasing foam dressing in delayed healing leg ulcers - a health-economic analysis. International Wound Journal, 2 (2), 150-160. (doi:10.1111/j.1742-4801.2005.00083.x).

Record type: Article

Abstract

The aim of this analysis was to examine the cost-effectiveness of Contreet Foam (A) in comparison with three other commonly used venous leg ulcer treatment protocols: Aquacel Ag (B), Actisorb Silver (C) and Iodoflex (D). A health-economic analysis reflecting the UK treatment practice and cost structure was performed. The analysis was set up to assess the cost of relative wound area reduction over a 4-week treatment period. The model was validated by a UK expert panel consisting of four wound care specialists. To assure that the 4-week model had a realistic link to cost-effectiveness of complete wound healing, a Markov analysis was also performed. Sensitivity analyses were carried out to ensure validity. Protocol A and C proved to be the most effective treatments. The mean relative reduction in wound area after 4 weeks of treatment was 50·2% (protocol A), 23·9% (protocol B), 44·6% (protocol C) and 36·0% (protocol D). Cost-effectiveness ratios showed that protocol A proved to be the most cost-effective treatment, and protocol B the least. The cost per percentage reduction in wound area was £9·50 for protocol A, compared to £16·50–17·60 for the other treatment options. The cost-effectiveness of complete healing (Markov analysis) and sensitivity analyses confirmed these results. Using Contreet Foam instead of the other dressing alternatives may imply savings of £2·2–4·4 million per year to the National Health Service.

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Published date: June 2005
Keywords: cost-effectiveness, contreet foam, silver, venous leg ulcer, antimicrobial treatment

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Local EPrints ID: 40818
URI: http://eprints.soton.ac.uk/id/eprint/40818
ISSN: 1742-4801
PURE UUID: ba1c5821-e8bd-48eb-97ab-83e79036a485

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Date deposited: 10 Jul 2006
Last modified: 15 Mar 2024 08:22

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Contributors

Author: Elizabeth Scanlon
Author: Tonny Karlsmark
Author: David J. Leaper
Author: Kate Carter
Author: Peter B. Poulsen
Author: Kristian Hart-Hansen
Author: Tina W. Hahn

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