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Attention bias to threat faces in children with bipolar disorder and comorbid lifetime anxiety disorders

Attention bias to threat faces in children with bipolar disorder and comorbid lifetime anxiety disorders
Attention bias to threat faces in children with bipolar disorder and comorbid lifetime anxiety disorders
Background: although comorbid anxiety disorders are common in children with bipolar disorder (BD), it is unclear how this comorbidity impacts the pathophysiology of the illness. Methods: pediatric BD with lifetime anxiety (BD+ANX, n = 20), BD without lifetime anxiety (BD-ANX, n = 11), and controls (n = 14) were administered the visual-probe paradigm, which assesses attention bias to threat faces. Results: bipolar disorder +ANX demonstrated a stronger bias toward threat relative to BD-ANX and controls; the latter two did not differ from each other. Conclusions: bipolar disorder +ANX showed a bias toward threat while, in two previous studies, anxious children showed a bias away from threat faces. Future studies should compare the pathophysiology of BD with and without a comorbid anxiety disorder and anxiety disorders presenting alone
anxiety, attention, bipolar disorder, faces, pediatric, threat
0006-3223
819-821
Brotman, Melissa A.
002528c9-0900-446e-ab28-ed31d0560eec
Rich, Brendan A.
e557364d-6abf-4232-9279-2c1d0449c938
Schmajuk, Mariana
912885d4-1acc-486b-b3b2-6835278aa6da
Reising, Michelle
18c79c32-02ff-490e-81a5-694b987d1633
Monk, Christopher S.
ac508cb8-4ce2-4653-a746-be909af175a4
Dickstein, Daniel P.
16aa65ab-5f32-4b7c-b07a-4d88fa6395ba
Mogg, Karin
5f1474af-85f5-4fd3-8eb6-0371be848e30
Bradley, Brendan P.
bdacaa6c-528b-4086-9448-27ebfe463514
Pine, Daniel S.
debffc1c-1efc-4bcf-81b3-87aadee1047d
Leibenluft, Ellen
c362a484-909b-4fbd-bcfd-814fedfe100f
Brotman, Melissa A.
002528c9-0900-446e-ab28-ed31d0560eec
Rich, Brendan A.
e557364d-6abf-4232-9279-2c1d0449c938
Schmajuk, Mariana
912885d4-1acc-486b-b3b2-6835278aa6da
Reising, Michelle
18c79c32-02ff-490e-81a5-694b987d1633
Monk, Christopher S.
ac508cb8-4ce2-4653-a746-be909af175a4
Dickstein, Daniel P.
16aa65ab-5f32-4b7c-b07a-4d88fa6395ba
Mogg, Karin
5f1474af-85f5-4fd3-8eb6-0371be848e30
Bradley, Brendan P.
bdacaa6c-528b-4086-9448-27ebfe463514
Pine, Daniel S.
debffc1c-1efc-4bcf-81b3-87aadee1047d
Leibenluft, Ellen
c362a484-909b-4fbd-bcfd-814fedfe100f

Brotman, Melissa A., Rich, Brendan A., Schmajuk, Mariana, Reising, Michelle, Monk, Christopher S., Dickstein, Daniel P., Mogg, Karin, Bradley, Brendan P., Pine, Daniel S. and Leibenluft, Ellen (2007) Attention bias to threat faces in children with bipolar disorder and comorbid lifetime anxiety disorders. Biological Psychiatry, 61 (6), 819-821. (doi:10.1016/j.biopsych.2006.08.021).

Record type: Article

Abstract

Background: although comorbid anxiety disorders are common in children with bipolar disorder (BD), it is unclear how this comorbidity impacts the pathophysiology of the illness. Methods: pediatric BD with lifetime anxiety (BD+ANX, n = 20), BD without lifetime anxiety (BD-ANX, n = 11), and controls (n = 14) were administered the visual-probe paradigm, which assesses attention bias to threat faces. Results: bipolar disorder +ANX demonstrated a stronger bias toward threat relative to BD-ANX and controls; the latter two did not differ from each other. Conclusions: bipolar disorder +ANX showed a bias toward threat while, in two previous studies, anxious children showed a bias away from threat faces. Future studies should compare the pathophysiology of BD with and without a comorbid anxiety disorder and anxiety disorders presenting alone

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More information

Published date: 2007
Keywords: anxiety, attention, bipolar disorder, faces, pediatric, threat

Identifiers

Local EPrints ID: 45080
URI: http://eprints.soton.ac.uk/id/eprint/45080
ISSN: 0006-3223
PURE UUID: e0579831-7f94-46bc-9df1-0f36869c6164
ORCID for Brendan P. Bradley: ORCID iD orcid.org/0000-0003-2801-4271

Catalogue record

Date deposited: 27 Mar 2007
Last modified: 16 Mar 2024 03:19

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Contributors

Author: Melissa A. Brotman
Author: Brendan A. Rich
Author: Mariana Schmajuk
Author: Michelle Reising
Author: Christopher S. Monk
Author: Daniel P. Dickstein
Author: Karin Mogg
Author: Daniel S. Pine
Author: Ellen Leibenluft

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