Nanoscale Ion mediated networks in bone: osteopontin can repeatedly dissipate large amounts of energy


Fantner, Georg E., Adams, Jonathan, Turner, Patricia, Thurner, Philipp J., Fisher, Larry W. and Hansma, Paul K. (2007) Nanoscale Ion mediated networks in bone: osteopontin can repeatedly dissipate large amounts of energy. Nano Letters, 7, (8), 2491-2498. (doi:10.1021/nl0712769).

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Original Publication URL: http://dx.doi.org/10.1021/nl0712769

Description/Abstract

In the nanocomposite bone, inorganic material is combined with several types of organic molecules, and these complexes have been proposed to increase the bone strength. Here we report on a mechanism of how one of these components, human osteopontin, forms large mechanical networks that can repeatedly dissipate energy through work against entropy by breaking sacrificial bonds and stretching hidden length. The behavior of these in vitro networks is similar to that of organic components in bone, acting as an adhesive layer in between mineralized fibrils.

Item Type: Article
ISSNs: 1530-6984 (print)
Related URLs:
Subjects: R Medicine > RZ Other systems of medicine
Q Science > QD Chemistry
Q Science > QP Physiology
Divisions: University Structure - Pre August 2011 > School of Engineering Sciences > Bioengineering Sciences
ePrint ID: 48335
Date Deposited: 13 Sep 2007
Last Modified: 27 Mar 2014 18:32
URI: http://eprints.soton.ac.uk/id/eprint/48335

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