Nanoscale Ion mediated networks in bone: osteopontin can repeatedly dissipate large amounts of energy
Fantner, Georg E., Adams, Jonathan, Turner, Patricia, Thurner, Philipp J., Fisher, Larry W. and Hansma, Paul K. (2007) Nanoscale Ion mediated networks in bone: osteopontin can repeatedly dissipate large amounts of energy. Nano Letters, 7, (8), 2491-2498. (doi:10.1021/nl0712769).
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Description/Abstract
In the nanocomposite bone, inorganic material is combined with several types of organic molecules, and these complexes have been proposed to increase the bone strength. Here we report on a mechanism of how one of these components, human osteopontin, forms large mechanical networks that can repeatedly dissipate energy through work against entropy by breaking sacrificial bonds and stretching hidden length. The behavior of these in vitro networks is similar to that of organic components in bone, acting as an adhesive layer in between mineralized fibrils.
| Item Type: | Article |
|---|---|
| ISSNs: | 1530-6984 (print) |
| Related URLs: | |
| Subjects: | R Medicine > RZ Other systems of medicine Q Science > QD Chemistry Q Science > QP Physiology |
| Divisions: | University Structure - Pre August 2011 > School of Engineering Sciences > Bioengineering Sciences |
| Item ID: | 48335 |
| Date Deposited: | 13 Sep 2007 |
| Last Modified: | 01 Jun 2011 09:23 |
| Contributors: | Fantner, Georg E. (Author) Adams, Jonathan (Author) Turner, Patricia (Author) Thurner, Philipp J. (Author) Fisher, Larry W. (Author) Hansma, Paul K. (Author) |
| Date: | July 2007 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/48335 |
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