Deep brain stimulation: a new treatment for hypertension?

Green, A.L., Wang, S., Bittar, R.G., Owen, S.L.F., Paterson, D.J., Stein, J.F., Bain, P.G., Shlugman, D. and Aziz, T.Z. (2007) Deep brain stimulation: a new treatment for hypertension? Journal of Clinical Neuroscience, 14, (6), 592-595. (doi:10.1016/j.jocn.2006.04.015).


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We report a 61-year-old hypertensive man who underwent deep brain stimulation of the periventricular/periaqueductal grey area for the relief of chronic neuropathic pain affecting his oral cavity and soft palate. During intraoperative stimulation, we were able to modulate his blood pressure up or down, depending on electrode location. This is the first evidence that hypertension could be effectively treated with electrical stimulation of the midbrain.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1016/j.jocn.2006.04.015
Additional Information:
ISSNs: 0967-5868 (print)
Related URLs:
Keywords: blood pressure, deep brain stimulation, periaqueductal grey, hypertension
Subjects: R Medicine > RV Botanic, Thomsonian, and eclectic medicine
T Technology > TA Engineering (General). Civil engineering (General)
Q Science > QP Physiology
Divisions : University Structure - Pre August 2011 > Institute of Sound and Vibration Research > Human Sciences
ePrint ID: 49591
Accepted Date and Publication Date:
June 2007Published
Date Deposited: 19 Nov 2007
Last Modified: 31 Mar 2016 12:26

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