Deep brain stimulation for neuropathic pain

Owen, S.L., Green, A.L., Nandi, D.D., Bittar, R.G., Wang, ShouYan and Aziz, T.Z. (2006) Deep brain stimulation for neuropathic pain. Neuromodulation, 9, (2), 100-106. (doi:10.1111/j.1525-1403.2006.00049.x).


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To determine whether deep brain stimulation is an effective treatment for neuropathic pain of varied etiology. Material and Methods.?

Thirty-four patients with intractable neuropathic pain were prospectively studied using visual analog scores, McGill Pain Questionnaire, and Quality of Life Questionnaires (EUROQOL EQ-5D VAS, and SF-36 v-2). Patients had either deep brain stimulation of either the periventricular gray or ventroposterolateral nucleus of the thalamus, or both. Results.?

Seventy-six percent of patients underwent permanent implantation. Overall reduction of pain intensity was 54%. The burning component of pain improved by 77%. Health-related quality of life improved by 38%. Conclusions.?

Deep brain stimulation is an effective treatment for neuropathic pain. The factors that influence outcome, including etiology and site of stimulation, are discussed.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1111/j.1525-1403.2006.00049.x
ISSNs: 0065-1419 (print)
Related URLs:
Keywords: deep brain stimulation, neuropathic pain, quality of life
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
R Medicine > RV Botanic, Thomsonian, and eclectic medicine
T Technology > TA Engineering (General). Civil engineering (General)
Q Science > QP Physiology
Divisions : University Structure - Pre August 2011 > Institute of Sound and Vibration Research > Human Sciences
ePrint ID: 49594
Accepted Date and Publication Date:
Date Deposited: 21 Nov 2007
Last Modified: 31 Mar 2016 12:26

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