Infection of Drosophila melanogaster by Tubulinosema kingi: stage-specific susceptibility and within-host proliferation
Vijendravarma, Roshan K., Godfray, H. Charles J. and Kraaijeveld, Alex R. (2008) Infection of Drosophila melanogaster by Tubulinosema kingi: stage-specific susceptibility and within-host proliferation. Journal of Invertebrate Pathology, 99, 239-241. (doi:10.1016/j.jip.2008.02.014)
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Official URL: http://dx.doi.org/10.1016/j.jip.2008.02.014
Description/Abstract
Despite its importance as a model organism very little is known about the interaction between Drosophila and its microsporidian pathogens. Here we report on the relative
susceptibility of D. melanogaster life-history stages to infection by Tubulinosema
kingi, and on patterns of pathogen proliferation. We find that only larvae can be
infected, and that this susceptibility decreases with larval age. Following infection, the
pathogen shows little subsequent proliferation in larvae, a limited amount in pupae
while it replicates greatly in adults. We present evidence that the host launches a
cellular immune response after infection with the pathogen, although its effectiveness
remains to be demonstrated.
| Item Type: | Article |
|---|---|
| ISSN: | 0022-2011 (print) |
| Uncontrolled Keywords: | drosophila melanogaster, tubulinosema kingi, diptera, microsporidia, susceptibility, proliferation, immune response, host-pathogen interaction |
| Related URLs: | http://www.sciencedirect.com/s...78db44bffa http://dx.doi.org/10.1016/j.ji...008.02.014 |
| Subjects: | Q Science > QL Zoology Q Science > QR Microbiology |
| Divisions: | University Structure - Pre August 2011 > School of Biological Sciences |
| ePrint ID: | 50565 |
| Deposited On: | 05 Mar 2008 |
| Last Modified: | 01 Jun 2011 05:43 |
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