Allostatic load, perceived stress, and health: a prospective study in two age groups. [in issue: Biobehavioral Stress Response Protective and Damaging Effects]


Hellhammer, J., Schlotz, W., Stone, A.A., Pirke, K.M. and Hellhammer, D. (2004) Allostatic load, perceived stress, and health: a prospective study in two age groups. [in issue: Biobehavioral Stress Response Protective and Damaging Effects]. Annals of the New York Academy of Sciences, 1032, 8-13. (doi:10.1196/annals.1314.002).

Download

Full text not available from this repository.

Original Publication URL: http:dx.doi.org/10.1196/annals.1314.002

Description/Abstract

Overactivity of the hypothalamus-pituitary-adrenal axis (HPAA) has been observed in the presence of acute stress and, under chronic conditions, in disorders such as depression and anorexia nervosa as well as in cardiovascular and metabolic disorders. However, there may be other stress-related disorders (fatigue, pain, etc) that seem to be associated with mild hypocortisolism. This suggests that two major subtypes of the HPAA response to stress need to be discriminated. In this study, we investigated 76 subjects with and without hypocortisolism, respectively, over a 1-year period. Surprisingly, hypocortisolemic subjects had a lower allostatic load but they scored higher on measures of depression, perceived stress, and physical complaints. We propose a protective role of the hypocortisolemic stress response on cardiovascular and metabolic disorders, particularly in the elderly.

Item Type: Article
ISSNs: 0077-8923 (print)
Related URLs:
Keywords: cortisol, allostatic load, protective and damaging effects, hypocortisolism, chronic stress, health, fibrinogen, whr
Subjects: H Social Sciences > HT Communities. Classes. Races
R Medicine > RC Internal medicine
B Philosophy. Psychology. Religion > BF Psychology
Divisions: University Structure - Pre August 2011 > School of Psychology > Division of Human Wellbeing
ePrint ID: 52579
Date Deposited: 10 Jul 2008
Last Modified: 27 Mar 2014 18:35
URI: http://eprints.soton.ac.uk/id/eprint/52579

Actions (login required)

View Item View Item