2 '-O-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices


Brennan, Lavinia, Peng, Guomei, Srinivasan, Natarajan, Fox, Keith R. and Brown, Tom (2007) 2 '-O-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices. Nucleosides, Nucleotides and Nucleic Acids, 26, (10-12), 1283-1286. (doi:10.1080/15257770701530525).

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Description/Abstract

The nucleoside analogues 2'-O-dimethylaminoethoxy uridine and 5-dimethylaminopropargyl deoxyuridine have been synthesised and incorporated into oligonucleotides. Their triplex-stabilising properties have been determined in fluorescence melting experiments.

Item Type: Article
ISSNs: 1525-7770 (print)
Related URLs:
Keywords: antigene, triple helices, triplexes, at recognition
Subjects: Q Science > QD Chemistry
Q Science > QH Natural history > QH301 Biology
Divisions: University Structure - Pre August 2011 > School of Biological Sciences
University Structure - Pre August 2011 > School of Chemistry
Item ID: 54252
Date Deposited: 30 Jul 2008
Last Modified: 23 Jul 2012 10:37
Contributors: Brennan, Lavinia (Author)
Peng, Guomei (Author)
Srinivasan, Natarajan (Author)
Fox, Keith R. (Author)
Brown, Tom (Author)
Date: October 2007
Status: Published
URI: http://eprints.soton.ac.uk/id/eprint/54252

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