Synthesis of anthraquinone oligonucleotides for triplex stabilization


Zhao, Zhengyun, Peng, Guomei, Michels, Jan, Fox, Keith R. and Brown, Tom (2007) Synthesis of anthraquinone oligonucleotides for triplex stabilization. Nucleosides, Nucleotides and Nucleic Acids, 26, (8 & 9), 921-925. (doi:10.1080/15257770701506491).

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Description/Abstract

The synthesis of two anthraquinone phosphoramidites is described. In both cases the anthraquinone moiety is attached via a linker to the 5-position of a uracil base, allowing incorporation at any thymidine position in an oligonucleotide sequence. Anthraquinone-modified oligonucleotides have potential applications as triplex stabilizers and fluorescence quenchers.

Item Type: Article
ISSNs: 1525-7770 (print)
Related URLs:
Keywords: anthraquinone, triplex stabilizers, fluorescence quenchers
Subjects: Q Science > QD Chemistry
Q Science > QH Natural history > QH301 Biology
Divisions: University Structure - Pre August 2011 > School of Biological Sciences
University Structure - Pre August 2011 > School of Chemistry
ePrint ID: 54411
Date Deposited: 30 Jul 2008
Last Modified: 27 Mar 2014 18:37
URI: http://eprints.soton.ac.uk/id/eprint/54411

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