Synthesis of anthraquinone oligonucleotides for triplex stabilization
Zhao, Zhengyun, Peng, Guomei, Michels, Jan, Fox, Keith R. and Brown, Tom (2007) Synthesis of anthraquinone oligonucleotides for triplex stabilization. Nucleosides, Nucleotides and Nucleic Acids, 26, (8 & 9), 921-925. (doi:10.1080/15257770701506491).
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Original Publication URL: http://dx.doi.org/10.1080/15257770701506491
Description/Abstract
The synthesis of two anthraquinone phosphoramidites is described. In both cases the anthraquinone moiety is attached via a linker to the 5-position of a uracil base, allowing incorporation at any thymidine position in an oligonucleotide sequence. Anthraquinone-modified oligonucleotides have potential applications as triplex stabilizers and fluorescence quenchers.
| Item Type: | Article |
|---|---|
| ISSNs: | 1525-7770 (print) |
| Related URLs: | |
| Keywords: | anthraquinone, triplex stabilizers, fluorescence quenchers |
| Subjects: | Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology |
| Divisions: | University Structure - Pre August 2011 > School of Biological Sciences University Structure - Pre August 2011 > School of Chemistry |
| Item ID: | 54411 |
| Date Deposited: | 30 Jul 2008 |
| Last Modified: | 01 Jun 2011 07:03 |
| Contributors: | Zhao, Zhengyun (Author) Peng, Guomei (Author) Michels, Jan (Author) Fox, Keith R. (Author) Brown, Tom (Author) |
| Date: | August 2007 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/54411 |
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