Prevalence of sensitization reported and objectively assessed food hypersensitivity amongst six-year-old children: a population-based study.
Prevalence of sensitization reported and objectively assessed food hypersensitivity amongst six-year-old children: a population-based study.
There is a paucity of information on food hypersensitivity (FHS) in young children and there are even fewer population-based studies in this area. The aim of the study was to determine the prevalence of parentally reported FHS, and objectively diagnosed FHS amongst six-year-old children and to establish the rates of sensitization to key allergens. This population-based cohort study recruited 798 6-year-olds resident on the Isle of Wight (UK). Sensitization rates, reported rates of FHS and objectively assessed FHS was established using food challenges. A total of 94 (11.8%) 6 yr olds reported a problem with a food or food ingredient. The rate of sensitization to the pre-defined panel of food allergens was 25/700 (3.6%). Based on open food challenge and/or suggestive history and skin tests, the prevalence of FHS was 2.5% (95% CI 1.5-3.8). Based on double-blind challenges, a clinical diagnosis or suggestive history and positive skin tests, the prevalence was 1.6% (95% CI 0.9-2.7). The rates of perception of FHS are higher than the prevalence of sensitization to main food allergens and the prevalence of FHS based on food challenges. Milk, peanut and wheat were the key food allergens amongst those with positive challenges.
356-363
Venter, Carina
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Pereira, Brett
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Grundy, Jane
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Clayton, C.B.
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Arshad, S.H.
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Dean, Taraneh
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August 2006
Venter, Carina
a9b7dd5e-b0cb-4068-be82-e15b587cc20b
Pereira, Brett
58a6cbce-4ea5-41b0-9b85-794c6c653e29
Grundy, Jane
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Clayton, C.B.
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Arshad, S.H.
917e246d-2e60-472f-8d30-94b01ef28958
Dean, Taraneh
1bb6a824-55c0-484a-a3f9-3f4ea60912fc
Venter, Carina, Pereira, Brett, Grundy, Jane, Clayton, C.B., Arshad, S.H. and Dean, Taraneh
(2006)
Prevalence of sensitization reported and objectively assessed food hypersensitivity amongst six-year-old children: a population-based study.
Pediatric Allergy and Immunology, 17 (5), .
(doi:10.1111/j.1399-3038.2006.00428.x).
Abstract
There is a paucity of information on food hypersensitivity (FHS) in young children and there are even fewer population-based studies in this area. The aim of the study was to determine the prevalence of parentally reported FHS, and objectively diagnosed FHS amongst six-year-old children and to establish the rates of sensitization to key allergens. This population-based cohort study recruited 798 6-year-olds resident on the Isle of Wight (UK). Sensitization rates, reported rates of FHS and objectively assessed FHS was established using food challenges. A total of 94 (11.8%) 6 yr olds reported a problem with a food or food ingredient. The rate of sensitization to the pre-defined panel of food allergens was 25/700 (3.6%). Based on open food challenge and/or suggestive history and skin tests, the prevalence of FHS was 2.5% (95% CI 1.5-3.8). Based on double-blind challenges, a clinical diagnosis or suggestive history and positive skin tests, the prevalence was 1.6% (95% CI 0.9-2.7). The rates of perception of FHS are higher than the prevalence of sensitization to main food allergens and the prevalence of FHS based on food challenges. Milk, peanut and wheat were the key food allergens amongst those with positive challenges.
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Published date: August 2006
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Local EPrints ID: 59421
URI: http://eprints.soton.ac.uk/id/eprint/59421
ISSN: 0905-6157
PURE UUID: 31953b01-8db1-4186-ae0f-5d824cae4422
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Date deposited: 02 Sep 2008
Last modified: 15 Mar 2024 11:16
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Author:
Carina Venter
Author:
Brett Pereira
Author:
Jane Grundy
Author:
C.B. Clayton
Author:
Taraneh Dean
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