The delivery of PEBBLE nanosensors to measure the intracellular environment
Webster, A., Houghton, F.D., Leese, H.J. and Aylott, J.W. (2007) The delivery of PEBBLE nanosensors to measure the intracellular environment. Biochemical Society Transactions, 35, (3), 538-543.
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Description/Abstract
Cellular introduction of PEBBLEs (photonic explorers for bioanalysis with biologically localized embedding) has been investigated by a wide variety of methods in a range of cell types. These methods include surface functionalization with CPPs (cell-penetrating peptides), pinocytosis, commercial lipid transfection agents, cytochalasin D, picoinjection, and Gene gun bombardment. This paper will overview several of the most popular methods used for the introduction of PEBBLE nanosensors to the cellular environment and discuss the efficacy of the techniques.
| Item Type: | Article |
|---|---|
| Additional Information: | Biochemical Society Focused Meetings |
| ISSNs: | 0300-5127 (print) |
| Related URLs: | |
| Keywords: | biolistics, delivery, transfection, mice, review, intracellular fluid, research, rats, nanotechnology, biosensing techniques, animals, phagocytosis, microscopy, humans, paper, cytochalasin d, methods, environment, peptides, confocal, agents, research support, pinocytosis, microinjections, chemistry |
| Subjects: | T Technology > TP Chemical technology Q Science > QR Microbiology Q Science > QC Physics |
| Divisions: | University Structure - Pre August 2011 > School of Medicine |
| Item ID: | 60404 |
| Date Deposited: | 02 Sep 2008 |
| Last Modified: | 23 Jul 2012 11:24 |
| Contributors: | Webster, A. (Author) Houghton, F.D. (Author) Leese, H.J. (Author) Aylott, J.W. (Author) |
| Date: | 2007 |
| Additional Information: | Biochemical Society Focused Meetings |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/60404 |
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