The delivery of PEBBLE nanosensors to measure the intracellular environment

Webster, A., Houghton, F.D., Leese, H.J. and Aylott, J.W. (2007) The delivery of PEBBLE nanosensors to measure the intracellular environment. Biochemical Society Transactions, 35, (3), 538-543.


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Cellular introduction of PEBBLEs (photonic explorers for bioanalysis with biologically localized embedding) has been investigated by a wide variety of methods in a range of cell types. These methods include surface functionalization with CPPs (cell-penetrating peptides), pinocytosis, commercial lipid transfection agents, cytochalasin D, picoinjection, and Gene gun bombardment. This paper will overview several of the most popular methods used for the introduction of PEBBLE nanosensors to the cellular environment and discuss the efficacy of the techniques.

Item Type: Article
Additional Information: Biochemical Society Focused Meetings
ISSNs: 0300-5127 (print)
Related URLs:
Keywords: biolistics, delivery, transfection, mice, review, intracellular fluid, research, rats, nanotechnology, biosensing techniques, animals, phagocytosis, microscopy, humans, paper, cytochalasin d, methods, environment, peptides, confocal, agents, research support, pinocytosis, microinjections, chemistry
Subjects: T Technology > TP Chemical technology
Q Science > QR Microbiology
Q Science > QC Physics
Divisions : University Structure - Pre August 2011 > School of Medicine
ePrint ID: 60404
Accepted Date and Publication Date:
Date Deposited: 02 Sep 2008
Last Modified: 31 Mar 2016 12:43

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