Non-bacterial thrombotic endocarditis

Asopa, Sanjay, Patel, Anish, Khan, Omar A., Sharma, Rajan and Ohri, Sunil K. (2007) Non-bacterial thrombotic endocarditis. European Journal of Cardio-Thoracic Surgery, 32, (5), 696-701. (doi:10.1016/j.ejcts.2007.07.029).


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Non-bacterial thrombotic endocarditis (NBTE) is a disease characterised by the presence of vegetations on cardiac valves, which consist of fibrin and platelet aggregates and devoid of inflammation or bacteria. NBTE has increasingly been recognised as a condition associated with numerous diseases and a potentially life-threatening source of thromboembolism. NBTE is not a common entity; however it is frequently underestimated, probably due to underlying diseases (cancer, autoimmune disorders, HIV). NBTE is difficult to diagnose and relies on strong clinical suspicion. NBTE is also difficult to manage and each case should be individually managed by identifying and treating the underlying pathology. Surgical intervention is not recommended unless the patient is in acute congestive failure.

Item Type: Article
ISSNs: 1010-7940 (print)
Related URLs:
Keywords: endocarditis, pathology, etiology, thromboembolism, review, cancer, disease, inflammation, heart valve diseases, humans
Subjects: R Medicine > RB Pathology
R Medicine > RD Surgery
Divisions: University Structure - Pre August 2011 > School of Medicine > Developmental Origins of Health and Disease
ePrint ID: 60877
Date Deposited: 26 Sep 2008
Last Modified: 06 Aug 2015 02:49

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