IQ in late adolescence/early adulthood, risk factors in middle-age and later coronary heart disease mortality in men: the Vietnam Experience Study


Batty, G. D., Shipley, M. J., Mortensen, L. H., Gale, C. R. and Deary, I. J. (2008) IQ in late adolescence/early adulthood, risk factors in middle-age and later coronary heart disease mortality in men: the Vietnam Experience Study. European Journal Cardiovascular Prevention & Rehabilitation, 15, (3), 359-361.

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Description/Abstract

OBJECTIVE: Examine the relation between IQ in early adulthood and later coronary heart disease (CHD) mortality, and assess the extent to which established risk factors measured in middle-age might explain this gradient.

DESIGN: Cohort study of 4316 male former Vietnam-era US army personnel with IQ scores (mean age 20.4 years), risk factor data (mean age 38.3 years) and 15 years mortality surveillance.

RESULTS: In age-adjusted analyses, lower IQ scores were associated with an increased rate of CHD mortality (hazard ratio per SD decrease in IQ; 95% confidence interval: 1.34; 1.00, 1.79). Adjustment for later chronic disease (1.22; 0.91, 1.64), behavioural (1.29; 0.95, 1.74) and physiological risk factors (1.19; 0.88, 1.62) led to some attenuation of this gradient. This attenuation was particularly pronounced on adding socioeconomic indices to the multivariable model when the IQ-CHD relation was eliminated (1.05; 0.73, 1.52). A similar pattern of association was apparent when cardiovascular disease was the outcome of interest.

CONCLUSION: High IQ may lead to educational success, well remunerated and higher prestige employment, and this pathway may confer cardio-protection.

Item Type: Article
ISSNs: 1741-8267 (print)
Related URLs:
Keywords: cardiovascular-disease, coronary heart disease, men, risk, cardiovascular, middle age, male, cohort studies, risk factors, cohort, disease, heart, employment, cardiovascular disease, mortality, chronic disease
Subjects: H Social Sciences > HN Social history and conditions. Social problems. Social reform
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
L Education > L Education (General)
Divisions: University Structure - Pre August 2011 > School of Medicine
ePrint ID: 60901
Date Deposited: 24 Sep 2008
Last Modified: 27 Mar 2014 18:42
URI: http://eprints.soton.ac.uk/id/eprint/60901

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