The effect of altering the 20:5n-3 and 22:6n-3 content of a meal on the postprandial incorporation of n-3 polyunsaturated fatty acids into plasma triacylglycerol and non-esterified fatty acids in humans


Burdge, G.C., Sala-Vila, A., West, A.L., Robson, H.J.L., Le Fevre, L.W., Powell, J. and Calder, P.C. (2007) The effect of altering the 20:5n-3 and 22:6n-3 content of a meal on the postprandial incorporation of n-3 polyunsaturated fatty acids into plasma triacylglycerol and non-esterified fatty acids in humans. Prostaglandins, leukotrienes, and essential fatty acids, 77, (1), 59-65. (doi:10.1016/j.plefa.2007.06.003).

Download

Full text not available from this repository.

Description/Abstract

Previous studies suggest that consuming meals containing large amounts of fish oil is associated with selective postprandial incorporation of 20:5n-3 and 22:6n-3 into plasma non-esterified fatty acids (NEFA). We investigated the effect of consuming meals containing different amounts of 20:5n-3 and 22:6n-3 comparable to dietary habits of western populations on the postprandial incorporation of 18:3n-3, 20:5n-3 and 22:6n-3 into plasma triacylglycerol (TAG) and NEFA over 6h in middle aged subjects. 20:5n-3 incorporation into plasma TAG was greater than 22:6n-3 irrespective of the test meal. Conversely, 22:6n-3 incorporation into plasma NEFA was greater than 20:5n-3, irrespective of the test meal. There was no effect of the amount of 20:5n-3+22:6n-3 in the test meal on the 18:3n-3 incorporation into plasma TAG or NEFA. These findings suggest differential metabolism of 20:5n-3 and 22:6n-3 in the postprandial period when consumed in amounts typical of western dietary habits.

Item Type: Article
Additional Information:
ISSNs: 0952-3278 (print)
Related URLs:
Keywords: humans, male, aged, human, nutrition, postprandial period, metabolism, blood, middle aged,nonesterified, analysis, docosahexaenoic acids, fatty acids, administration & dosage, triglycerides, time factors,acid, female, fatty acids, eicosapentaenoic acid, sex factors, physiology
Subjects: R Medicine > R Medicine (General)
Q Science > QP Physiology
Divisions: University Structure - Pre August 2011 > School of Medicine
ePrint ID: 60944
Date Deposited: 23 Sep 2008
Last Modified: 27 Mar 2014 18:43
URI: http://eprints.soton.ac.uk/id/eprint/60944

Actions (login required)

View Item View Item