Three-dimensional ultrasonographic reslicing of the fetal brain to assist prenatal diagnosis of central nervous system anomalies

Kalache, K.D., Eder, K., Esser, T., Proquitte, H., Stoltenburg-Didinger, G., Hartung, J.P. and Bamberg, C. (2006) Three-dimensional ultrasonographic reslicing of the fetal brain to assist prenatal diagnosis of central nervous system anomalies. Journal of Ultrasound in Medicine, 25 (4), 509-514.

Abstract

OBJECTIVES: The purpose of this study was to evaluate the potential of 3-dimensional ultrasonographic planar and nonplanar reslicing techniques.
METHODS: Fetuses with severe brain anomalies diagnosed by means of 2-dimensional ultrasonography were prospectively included in the study. Good-quality 3-dimensional volumes of the fetal head were obtained in each case. Subsequently, these volumes were reviewed with use of 3-dimensional extended imaging with Oblique View and DynamicMR (Medison Co, Ltd, Seoul, Korea).
RESULTS: Eight fetuses (mean gestational age, 23 weeks; range, 20-30 weeks) with the following central nervous system anomalies were examined: semilobar holoprosencephaly, absent cavum septum pellucidum, porencephaly in twin-to-twin transfusion syndrome, partial agenesis of the corpus callosum, Dandy-Walker variant, open-lip schizencephaly, aneurysm of the vein of Galen, and dilated cavum vergae.
CONCLUSIONS: Planar and nonplanar reslicing of the volumes delivered informative images in any reconstructed plane. One important prerequisite, however, was the absence of acoustic shadowing during data acquisition.

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