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Health-related quality of life in patients with pain related to depression (Results from UK subsample of the European Finder study)

Health-related quality of life in patients with pain related to depression (Results from UK subsample of the European Finder study)
Health-related quality of life in patients with pain related to depression (Results from UK subsample of the European Finder study)
Objectives: To estimate the health-related quality of life (HRQOL) and impact of concurrent pain on HRQOL in patients seeking treatment for depression in a 6 month observational study in the United Kingdom (subsample results from pan-European study).
Methodology: HRQOL was measured using two generic quality of life instruments: the Short Form 36 Health Status Survey (SF-36) and the EuroQol (EQ-5D). Pain was assessed using a visual analogue scale (range 0-100, no/mild pain [NMP] 0-29, clinically significant pain ?30).
Results: 608 eligible patients were enrolled, mean age 42.8 years (SD 14.7) and 61.2% were female. 49.4% of patients reported NMP; 10.8% had significant pain from a co-morbid medical condition known to cause pain (PMC) and 39.8% had significant pain associated with a medical disorder not known to cause pain or without further co-morbidity (PD). SF-36 physical component scores were lowest in the PMC group, 36.7 (SD 9.7); with improving scores in the PD group, 44.4 (SD 10.0) and the NMP group, 54.5 (SD 8.3). There was no marked variation in mental component summary scores between the groups; 23.0 (SD 8.5), 20.4 (SD 9.1) and 21.7 (SD 10.8) respectively. A similar trend in HRQOL loss was observed for the EQ-5D health state index, where scores of 0.30 (SD 0.32), 0.41 (SD 0.30) and 0.60 (SD 0.25) were observed respectively.
Conclusions: A high proportion of patients presented with pain presumably related to depression. The presence of concurrent pain appears to be associated with reductions in SF-36 physical component scores and overall HRQOL (EQ-5D).
patients, depression, quality of life
0924-9338
p.S222
Azough, A.
ff1e4b50-6879-4335-a703-a6c896fe5e74
Gupta, R.D.A.S.
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Wong, B.
664e02f9-7177-471a-aea5-f9e1e3b15572
Barradell, C.
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Jodgessar, Y.
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Poole, L.
eb4310d0-5c02-4ed7-86a6-72c38912704f
Watkins, J.
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Tylee, A.
ca759e2d-ee8c-465d-b574-c0ff82ee4d47
Peveler, R.
93198224-78d9-4c1f-9c07-fdecfa69cf96
Gandhi, P.
28a0973a-caaa-495a-94bb-4320e83e9716
Azough, A.
ff1e4b50-6879-4335-a703-a6c896fe5e74
Gupta, R.D.A.S.
92eb811a-3fef-4bd3-a35d-c067634327e4
Wong, B.
664e02f9-7177-471a-aea5-f9e1e3b15572
Barradell, C.
7f159ff6-bf4d-472e-8406-3394d29ed77e
Jodgessar, Y.
7352f6ac-6f59-4961-b58f-c6240dfd3084
Poole, L.
eb4310d0-5c02-4ed7-86a6-72c38912704f
Watkins, J.
bdd2fba0-01db-49ed-8efa-405c0b3be913
Tylee, A.
ca759e2d-ee8c-465d-b574-c0ff82ee4d47
Peveler, R.
93198224-78d9-4c1f-9c07-fdecfa69cf96
Gandhi, P.
28a0973a-caaa-495a-94bb-4320e83e9716

Azough, A., Gupta, R.D.A.S., Wong, B., Barradell, C., Jodgessar, Y., Poole, L., Watkins, J., Tylee, A., Peveler, R. and Gandhi, P. (2007) Health-related quality of life in patients with pain related to depression (Results from UK subsample of the European Finder study). European Psychiatry, 22 (Supplement 1), p.S222. (doi:10.1016/j.eurpsy.2007.01.742).

Record type: Article

Abstract

Objectives: To estimate the health-related quality of life (HRQOL) and impact of concurrent pain on HRQOL in patients seeking treatment for depression in a 6 month observational study in the United Kingdom (subsample results from pan-European study).
Methodology: HRQOL was measured using two generic quality of life instruments: the Short Form 36 Health Status Survey (SF-36) and the EuroQol (EQ-5D). Pain was assessed using a visual analogue scale (range 0-100, no/mild pain [NMP] 0-29, clinically significant pain ?30).
Results: 608 eligible patients were enrolled, mean age 42.8 years (SD 14.7) and 61.2% were female. 49.4% of patients reported NMP; 10.8% had significant pain from a co-morbid medical condition known to cause pain (PMC) and 39.8% had significant pain associated with a medical disorder not known to cause pain or without further co-morbidity (PD). SF-36 physical component scores were lowest in the PMC group, 36.7 (SD 9.7); with improving scores in the PD group, 44.4 (SD 10.0) and the NMP group, 54.5 (SD 8.3). There was no marked variation in mental component summary scores between the groups; 23.0 (SD 8.5), 20.4 (SD 9.1) and 21.7 (SD 10.8) respectively. A similar trend in HRQOL loss was observed for the EQ-5D health state index, where scores of 0.30 (SD 0.32), 0.41 (SD 0.30) and 0.60 (SD 0.25) were observed respectively.
Conclusions: A high proportion of patients presented with pain presumably related to depression. The presence of concurrent pain appears to be associated with reductions in SF-36 physical component scores and overall HRQOL (EQ-5D).

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More information

Published date: March 2007
Additional Information: 15th AEP Congress - Abstract book, 15th AEP Congress
Keywords: patients, depression, quality of life

Identifiers

Local EPrints ID: 62232
URI: http://eprints.soton.ac.uk/id/eprint/62232
ISSN: 0924-9338
PURE UUID: dffc9c6e-34fe-4c66-8c67-786b9198f0d5
ORCID for R. Peveler: ORCID iD orcid.org/0000-0001-5596-9394

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Date deposited: 30 Oct 2008
Last modified: 16 Mar 2024 02:38

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Contributors

Author: A. Azough
Author: R.D.A.S. Gupta
Author: B. Wong
Author: C. Barradell
Author: Y. Jodgessar
Author: L. Poole
Author: J. Watkins
Author: A. Tylee
Author: R. Peveler ORCID iD
Author: P. Gandhi

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