The complex route to MHC class I-peptide complexes
Elliott, T. and Neefjes, J. (2006) The complex route to MHC class I-peptide complexes. Cell, 127, (2), 249-251. (doi:10.1016/j.cell.2006.10.001).
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Original Publication URL: http://dx.doi.org/10.1016/j.cell.2006.10.001
Description/Abstract
The loading of peptides into the groove of MHC class I molecules prior to antigen presentation is a complex process. In this issue of Cell, Park et al. (2006) show that peptide loading gets a helping hand from a resident ER enzyme called protein disulfide isomerase, a chaperone that has oxidoreductase activity
| Item Type: | Article |
|---|---|
| ISSNs: | 0092-8674 (print) |
| Related URLs: | |
| Keywords: | cell, antigen, loading complex, time, protein, molecules, antigen presentation |
| Subjects: | R Medicine |
| Divisions: | University Structure - Pre August 2011 > School of Medicine > Cancer Sciences |
| Item ID: | 62730 |
| Date Deposited: | 11 Sep 2008 |
| Last Modified: | 20 Jul 2012 03:05 |
| Contributors: | Elliott, T. (Author) Neefjes, J. (Author) |
| Date: | 2006 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/62730 |
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