Autism symptoms in attention-deficit/hyperactivity disorder: a familial trait which correlates with conduct, oppositional defiant, language and motor disorders


Mulligan, Aisling, Anney, Richard J.L., O'Regan, Myra, Chen, Wai, Butler, Louise, Fitzgerald, Michael, Buitelaar, Jan, Steinhausen, Hans-Christoph, Rothenberger, Aribert, Minderaa, Ruud, Nijmeijer, Judith, Hoekstra, Peter J., Oades, Robert D., Roeyers, Herbert, Buschgens, Cathelijne, Christiansen, Hanna, Franke, Barbara, Gabriels, Isabel, Hartman, Catharina, Kuntsi, Jonna, Marco, Rafaela, Meidad, Sheera, Mueller, Ueli, Psychogiou, Lamprini, Rommelse, Nanda, Thompson, Margaret, Uebel, Henrik, Banaschewski, Tobias, Ebstein, Richard, Eisenberg, Jacques, Manor, Iris, Miranda, Ana, Mulas, Fernando, Sergeant, Joseph, Sonuga-Barke, Edmund, Asherson, Phil, Faraone, Stephen V. and Gill, Michael (2009) Autism symptoms in attention-deficit/hyperactivity disorder: a familial trait which correlates with conduct, oppositional defiant, language and motor disorders. Journal of Autism and Developmental Disorders, 39, 197-209. (doi:10.1007/s10803-008-0621-3).

Download

Full text not available from this repository.

Description/Abstract

It is hypothesised that autism symptoms are present in Attention-Deficit/Hyperactivity Disorder (ADHD), are familial and index subtypes of ADHD. Autism symptoms were compared in 821 ADHD probands, 1050 siblings and 149 controls. Shared familiality of autism symptoms and ADHD was calculated using DeFries-Fulker analysis. Autism symptoms were higher in probands than siblings or controls, and higher in male siblings than male controls. Autism symptoms were familial, partly shared with familiality of ADHD in males. Latent class analysis using SCQ-score yielded five classes; Class 1(31%) had few autism symptoms and low comorbidity; Classes 2–4 were intermediate; Class 5(7%) had high autism symptoms and comorbidity. Thus autism symptoms in ADHD represent a familial trait associated with increased neurodevelopmental and oppositional/conduct disorders.

Item Type: Article
ISSNs: 0162-3257 (print)
Related URLs:
Keywords: adhd, autism, familiality, oppositional disorders, motor disorder, language disorder
Subjects: H Social Sciences > HQ The family. Marriage. Woman
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
B Philosophy. Psychology. Religion > BF Psychology
Divisions: University Structure - Pre August 2011 > School of Psychology > Division of Clinical Neuroscience
ePrint ID: 63807
Date Deposited: 05 Nov 2008
Last Modified: 27 Mar 2014 18:45
URI: http://eprints.soton.ac.uk/id/eprint/63807

Actions (login required)

View Item View Item