Applying bootstrap techniques to detect differences in auditory evoked potentials: possible use in anaesthesia monitoring


Notley, S.V., Bell, S.L., Simpson, D. and Smith, D.C. (2008) Applying bootstrap techniques to detect differences in auditory evoked potentials: possible use in anaesthesia monitoring. In, 4th IET International Conference on Advances in Medical, Signal and Information Processing, 2008. MEDSIP 2008. Proceedings of MEDSIP 2008 4th IET International Conference on Advances in Medical Signal and Information Processing USA, Institute of Electrical and Electronics Engineers, 1-4.

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Description/Abstract

This paper extends the use of the bootstrap method to detect significant differences between Auditory Evoked Potentials with the potential application of detecting changes due to anaesthesia. Monte-Carlo simulation confirmed the expected false positive rate for the technique. Recordings were made from normal hearing volunteers and patients undergoing anaesthesia using a number of stimulation paradigms. Although small differences in Evoked Potentials appear to the eye, these were not always found to be statistically significant which depends on both the magnitude of the difference and the quality of the recordings. Preliminary effects during anaesthesia are described.

Item Type: Book Section
ISBNs: 9780863419348 (hardback)
Related URLs:
Keywords: bootstrap, auditory evoked potentials, anaesthesia
Subjects: Q Science > Q Science (General)
T Technology > TA Engineering (General). Civil engineering (General)
Divisions: University Structure - Pre August 2011 > Institute of Sound and Vibration Research > Human Sciences
ePrint ID: 65201
Date Deposited: 23 Feb 2009
Last Modified: 14 Apr 2014 10:12
Research Funder: EPSRC
Projects:
Developing a clinical indicator of depth of anaesthesia based on auditory evoked potentials
Funded by: EPSRC (EP/D505593/1)
Led by: Steven Bell
1 February 2006 to 31 January 2009
Publisher: Institute of Electrical and Electronics Engineers
URI: http://eprints.soton.ac.uk/id/eprint/65201

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