Failure of elimination of amyloid-beta from the brain in Alzheimer's disease
de Silva, Prasanna, Carare, Roxana O. and Weller, Roy O. (2008) Failure of elimination of amyloid-beta from the brain in Alzheimer's disease. Progress in Neurology and Psychiatry, 12, (4), 6-10. (doi:10.1002/pnp.72).
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Original Publication URL: http://dx.doi.org/10.1002/pnp.72
Description/Abstract
Accumulation of amyloid-beta (A-beta) in the brain is a major cause of dementia in Alzheimer's disease.I n this article, Dr de Silva, Dr Carare and ProfessorWeller review the mechanisms for the elimination of A-beta from the brain, the reasons why these mechanisms fail in Alzheimer's disease, and how understanding this failure may lead to new approaches to the treatment of Alzheimer's disease.
| Item Type: | Article |
|---|---|
| ISSNs: | 1367-7543 (print) |
| Related URLs: | |
| Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Divisions: | University Structure - Pre August 2011 > School of Medicine > Medical Education |
| Item ID: | 66621 |
| Date Deposited: | 02 Jul 2009 |
| Last Modified: | 02 Mar 2012 13:34 |
| Contributors: | de Silva, Prasanna (Author) Carare, Roxana O. (Author) Weller, Roy O. (Author) |
| Date: | May 2008 |
| Status: | Published |
| URI: | http://eprints.soton.ac.uk/id/eprint/66621 |
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