Failure of elimination of amyloid-beta from the brain in Alzheimer's disease


de Silva, Prasanna, Carare, Roxana O. and Weller, Roy O. (2008) Failure of elimination of amyloid-beta from the brain in Alzheimer's disease. Progress in Neurology and Psychiatry, 12, (4), 6-10. (doi:10.1002/pnp.72).

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Original Publication URL: http://dx.doi.org/10.1002/pnp.72

Description/Abstract

Accumulation of amyloid-beta (A-beta) in the brain is a major cause of dementia in Alzheimer's disease.I n this article, Dr de Silva, Dr Carare and ProfessorWeller review the mechanisms for the elimination of A-beta from the brain, the reasons why these mechanisms fail in Alzheimer's disease, and how understanding this failure may lead to new approaches to the treatment of Alzheimer's disease.

Item Type: Article
Digital Object Identifier (DOI): doi:10.1002/pnp.72
ISSNs: 1367-7543 (print)
Related URLs:
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions : University Structure - Pre August 2011 > School of Medicine > Medical Education
ePrint ID: 66621
Accepted Date and Publication Date:
Status
May 2008Published
Date Deposited: 02 Jul 2009
Last Modified: 31 Mar 2016 12:52
URI: http://eprints.soton.ac.uk/id/eprint/66621

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