Failure of elimination of amyloid-beta from the brain in Alzheimer's disease
de Silva, Prasanna, Carare, Roxana O. and Weller, Roy O. (2008) Failure of elimination of amyloid-beta from the brain in Alzheimer's disease. Progress in Neurology and Psychiatry, 12, (4), 6-10. (doi:10.1002/pnp.72).
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Accumulation of amyloid-beta (A-beta) in the brain is a major cause of dementia in Alzheimer's disease.I n this article, Dr de Silva, Dr Carare and ProfessorWeller review the mechanisms for the elimination of A-beta from the brain, the reasons why these mechanisms fail in Alzheimer's disease, and how understanding this failure may lead to new approaches to the treatment of Alzheimer's disease.
|Digital Object Identifier (DOI):||doi:10.1002/pnp.72|
|Subjects:||R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry|
|Divisions:||University Structure - Pre August 2011 > School of Medicine > Medical Education
|Date Deposited:||02 Jul 2009|
|Last Modified:||06 Aug 2015 02:53|
|RDF:||RDF+N-Triples, RDF+N3, RDF+XML, Browse.|
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