Effectiveness of physiotherapy in Parkinson’s disease: the feasibility of a randomised controlled trial
Effectiveness of physiotherapy in Parkinson’s disease: the feasibility of a randomised controlled trial
To study the feasibility of a large randomised controlled trial (RCT) evaluating the effectiveness of physiotherapy in Parkinson's disease (PD), 173 patients were asked to participate in a study with random allocation to best practice physiotherapy, or to no physiotherapy. The primary outcome measures were the Parkinson's disease questionnaire-39, the Parkinson activity scale, and a patient preference outcome scale (PPOS). Only 14% of the patients could be included in the study. The PPOS showed the largest effect size (0.74) with a significant group effect (p<0.05). Specific alterations to the study design to ensure successful RCTs in this field are recommended.
feasibility studies, parkinson disease, patient selection, physical therapy, randomised controlled trials
115-121
Keus, S.H.
f839916b-f983-4bfe-932f-bdf94a0d7066
Bloem, B.R.
30a76ce6-c668-4411-b452-9e3b3a1935df
van Hilten, J.J.
df2b1730-7e36-4854-99dc-ebc5bedf3523
Ashburn, A.
818b9ce8-f025-429e-9532-43ee4fd5f991
Munneke, M.
65cfe2a3-a0be-4049-99d4-2a901927ca6a
March 2007
Keus, S.H.
f839916b-f983-4bfe-932f-bdf94a0d7066
Bloem, B.R.
30a76ce6-c668-4411-b452-9e3b3a1935df
van Hilten, J.J.
df2b1730-7e36-4854-99dc-ebc5bedf3523
Ashburn, A.
818b9ce8-f025-429e-9532-43ee4fd5f991
Munneke, M.
65cfe2a3-a0be-4049-99d4-2a901927ca6a
Keus, S.H., Bloem, B.R., van Hilten, J.J., Ashburn, A. and Munneke, M.
(2007)
Effectiveness of physiotherapy in Parkinson’s disease: the feasibility of a randomised controlled trial.
Parkinsonism and Related Disorders, 13 (2), .
(doi:10.1016/j.parkreldis.2006.07.007).
Abstract
To study the feasibility of a large randomised controlled trial (RCT) evaluating the effectiveness of physiotherapy in Parkinson's disease (PD), 173 patients were asked to participate in a study with random allocation to best practice physiotherapy, or to no physiotherapy. The primary outcome measures were the Parkinson's disease questionnaire-39, the Parkinson activity scale, and a patient preference outcome scale (PPOS). Only 14% of the patients could be included in the study. The PPOS showed the largest effect size (0.74) with a significant group effect (p<0.05). Specific alterations to the study design to ensure successful RCTs in this field are recommended.
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Published date: March 2007
Keywords:
feasibility studies, parkinson disease, patient selection, physical therapy, randomised controlled trials
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Local EPrints ID: 67126
URI: http://eprints.soton.ac.uk/id/eprint/67126
ISSN: 1353-8020
PURE UUID: 109e0b64-b39b-48b6-915b-45bffc8019e9
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Date deposited: 04 Aug 2009
Last modified: 13 Mar 2024 18:45
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Author:
S.H. Keus
Author:
B.R. Bloem
Author:
J.J. van Hilten
Author:
A. Ashburn
Author:
M. Munneke
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