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The leukaemia associated antigen, SSX2IP, is expressed during mitosis on the surface of myeloid leukaemia cells

The leukaemia associated antigen, SSX2IP, is expressed during mitosis on the surface of myeloid leukaemia cells
The leukaemia associated antigen, SSX2IP, is expressed during mitosis on the surface of myeloid leukaemia cells
We have shown for the first time the surface expression pattern of SSX2IP during mitosis which provides an interesting insight into SSX2IP protein expression in human malignancy. Therapeutically the removal of SSX2IP positive cells from AML patient stem cell harvests has the potential to reduce the tumour burden for patients whose graft fails or for patients who lack a suitable stem cell donor, although these possibilities require further investigation
SSX2IP, acute myeloid leukaemia, cell surface expression, mitosis, tumour associated antigen
0007-1048
668-669
Denniss, Frances A.K.
7fd95e83-79e6-4b81-b8a8-c8924f36450f
Breslin, Angela
60ec9b2c-ccff-42f9-9d31-3f48acff2f2f
Ingram, Wendy
852f9de8-07c4-4b3b-b70a-60b81e162561
Hardwick, Nicola R.
37c942dc-e5d8-4517-9049-d5a7172eb354
Mufti, Ghulam J.
940de420-bc41-4006-8517-f2c926ba70aa
Guinn, Barbar-Ann
596441de-9938-4994-9e04-0075cc32d205
Denniss, Frances A.K.
7fd95e83-79e6-4b81-b8a8-c8924f36450f
Breslin, Angela
60ec9b2c-ccff-42f9-9d31-3f48acff2f2f
Ingram, Wendy
852f9de8-07c4-4b3b-b70a-60b81e162561
Hardwick, Nicola R.
37c942dc-e5d8-4517-9049-d5a7172eb354
Mufti, Ghulam J.
940de420-bc41-4006-8517-f2c926ba70aa
Guinn, Barbar-Ann
596441de-9938-4994-9e04-0075cc32d205

Denniss, Frances A.K., Breslin, Angela, Ingram, Wendy, Hardwick, Nicola R., Mufti, Ghulam J. and Guinn, Barbar-Ann (2007) The leukaemia associated antigen, SSX2IP, is expressed during mitosis on the surface of myeloid leukaemia cells. British Journal of Haematology, 138 (5), 668-669. (doi:10.1111/j.1365-2141.2007.06706.x).

Record type: Article

Abstract

We have shown for the first time the surface expression pattern of SSX2IP during mitosis which provides an interesting insight into SSX2IP protein expression in human malignancy. Therapeutically the removal of SSX2IP positive cells from AML patient stem cell harvests has the potential to reduce the tumour burden for patients whose graft fails or for patients who lack a suitable stem cell donor, although these possibilities require further investigation

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More information

Submitted date: 2 August 2007
Published date: September 2007
Keywords: SSX2IP, acute myeloid leukaemia, cell surface expression, mitosis, tumour associated antigen

Identifiers

Local EPrints ID: 71033
URI: http://eprints.soton.ac.uk/id/eprint/71033
ISSN: 0007-1048
PURE UUID: f39cdc8a-5b20-4b6b-90cc-80d30bb1a1a7

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Date deposited: 14 Dec 2009
Last modified: 13 Mar 2024 20:17

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Contributors

Author: Frances A.K. Denniss
Author: Angela Breslin
Author: Wendy Ingram
Author: Nicola R. Hardwick
Author: Ghulam J. Mufti
Author: Barbar-Ann Guinn

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