The leukaemia associated antigen, SSX2IP, is expressed during mitosis on the surface of myeloid leukaemia cells
Denniss, Frances A.K., Breslin, Angela, Ingram, Wendy, Hardwick, Nicola R., Mufti, Ghulam J. and Guinn, Barbar-Ann (2007) The leukaemia associated antigen, SSX2IP, is expressed during mitosis on the surface of myeloid leukaemia cells. British Journal of Haematology, 138, (5), 668-669. (doi:10.1111/j.1365-2141.2007.06706.x).
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Description/Abstract
We have shown for the first time the surface expression pattern of SSX2IP during mitosis which provides an interesting insight into SSX2IP protein expression in human malignancy. Therapeutically the removal of SSX2IP positive cells from AML patient stem cell harvests has the potential to reduce the tumour burden for patients whose graft fails or for patients who lack a suitable stem cell donor, although these possibilities require further investigation
| Item Type: | Article |
|---|---|
| ISSNs: | 0007-1048 (print) |
| Related URLs: | |
| Keywords: | SSX2IP, acute myeloid leukaemia, cell surface expression, mitosis, tumour associated antigen |
| Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
| Divisions: | University Structure - Pre August 2011 > School of Medicine > Cancer Sciences |
| Item ID: | 71033 |
| Date Deposited: | 14 Dec 2009 |
| Last Modified: | 01 Jun 2011 15:12 |
| Contributors: | Denniss, Frances A.K. (Author) Breslin, Angela (Author) Ingram, Wendy (Author) Hardwick, Nicola R. (Author) Mufti, Ghulam J. (Author) Guinn, Barbar-Ann (Author) |
| Date: | September 2007 |
| Status: | Published |
| Contact Email Address: | B.Guinn@soton.ac.uk |
| URI: | http://eprints.soton.ac.uk/id/eprint/71033 |
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