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The functional resistance of bacterial biofilms

The functional resistance of bacterial biofilms
The functional resistance of bacterial biofilms
There is intellectual coherence when a physician must tell patients that the bacteria causing their infection have tested resistant to the empiric antibiotic therapy, and that an alternative drug must be used. In this chapter, we will concern ourselves with the growing number of bacterial infections in which antibiograms of the causative organism show sensitivity to standard antibiotics in readily attainable concentrations, but the infection fails to be cleared. This discrepancy is troubling and frustrating for patients, physicians, and diagnostic laboratories alike, but it can now be resolved by concepts that have become widely accepted in microbial ecology
9781603275927
Mayers, D.L. (ed.) Antimicrobial Drug Resistance
121-131
Humana
Fux, Christopher A.
b3d160df-13b0-416b-9ba6-b56864bc1204
Stoodley, Paul
08614665-92a9-4466-806e-20c6daeb483f
Shirtliff, Mark
eafbccd1-c97c-4107-b9de-f79133a2d8e6
Costerton, J. William
3561239b-c96e-41af-9228-4fc120466c4b
Fux, Christopher A.
b3d160df-13b0-416b-9ba6-b56864bc1204
Stoodley, Paul
08614665-92a9-4466-806e-20c6daeb483f
Shirtliff, Mark
eafbccd1-c97c-4107-b9de-f79133a2d8e6
Costerton, J. William
3561239b-c96e-41af-9228-4fc120466c4b

Fux, Christopher A., Stoodley, Paul, Shirtliff, Mark and Costerton, J. William (2009) The functional resistance of bacterial biofilms. In, Antimicrobial Drug Resistance. (Infectious Disease, Mayers, D.L. (ed.) Antimicrobial Drug Resistance, 2) Totowa, USA. Humana, pp. 121-131. (doi:10.1007/978-1-59745-180-2_11).

Record type: Book Section

Abstract

There is intellectual coherence when a physician must tell patients that the bacteria causing their infection have tested resistant to the empiric antibiotic therapy, and that an alternative drug must be used. In this chapter, we will concern ourselves with the growing number of bacterial infections in which antibiograms of the causative organism show sensitivity to standard antibiotics in readily attainable concentrations, but the infection fails to be cleared. This discrepancy is troubling and frustrating for patients, physicians, and diagnostic laboratories alike, but it can now be resolved by concepts that have become widely accepted in microbial ecology

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More information

Published date: 2009
Additional Information: The National Centre for Advanced Tribology at Southampton (nCATS)

Identifiers

Local EPrints ID: 71671
URI: http://eprints.soton.ac.uk/id/eprint/71671
ISBN: 9781603275927
PURE UUID: af612a7f-4c75-4045-8b97-6b2a551ce41d
ORCID for Paul Stoodley: ORCID iD orcid.org/0000-0001-6069-273X

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Date deposited: 21 Dec 2009
Last modified: 14 Mar 2024 02:55

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Contributors

Author: Christopher A. Fux
Author: Paul Stoodley ORCID iD
Author: Mark Shirtliff
Author: J. William Costerton

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