Onset time of topical analgesia with EMLA 5%: no reduction with glyceryl trinitrate


Nott, M.R., Clemson, C.J. and Peacock, J.L. (1996) Onset time of topical analgesia with EMLA 5%: no reduction with glyceryl trinitrate. European Journal of Anaesthesiology, 13, (1), 17-20.

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Description/Abstract

Many adults are distressed by painful investigations or treatment, including venepuncture. The early effects of Eutectic Mixture of Local Anaesthetics (EMLA) 5%, on relief of pinprick pain in the antecubital area was investigated and compared with EMLA plus glyceryl trinitrate and with a placebo cream in 100 patients. Topical analgesia after application of EMLA developed within 5 min in 69% and within 10 min in 83% of those tested, significantly different from placebo, (P = 0.01).

Item Type: Article
ISSNs: 0265-0215 (print)
Related URLs:
Subjects: R Medicine > R Medicine (General)
Divisions: University Structure - Pre August 2011 > School of Medicine > Community Clinical Sciences
ePrint ID: 72843
Date Deposited: 11 Mar 2010
Last Modified: 27 Mar 2014 18:51
URI: http://eprints.soton.ac.uk/id/eprint/72843

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