Asherman syndrome--one century later
Yu, Dan, Wong, Yat-May, Cheong, Ying, Xia, Enlan and Li, Tin-Chiu (2008) Asherman syndrome--one century later. Fertility and Sterility, 89, (4), 759-779. (doi:10.1016/j.fertnstert.2008.02.096).
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Description/Abstract
Objective: To provide an update on the current knowledge of Asherman syndrome.
Design:
Literature review.
Setting:
The worldwide reports of this disease.
Patient(s):
Patients with Asherman syndrome who presented with amenorrhea or hypomenorrhea, infertility, or recurrent pregnancy loss.
Intervention(s):
Hysteroscopy and hysteroscopic surgery have been the gold standard of diagnosis and treatment respectively for this condition.
Main outcome measure(s):
The etiology, pathology, symptomatology, diagnosis, treatment, and reproductive outcomes were analyzed.
Result(s):
This syndrome occurs mainly as a result of trauma to the gravid uterine cavity, which leads to the formation of intrauterine and/or intracervical adhesions. Despite the advances in hysteroscopic surgery, the treatment of moderate to severe Asherman syndrome still presents a challenge. Furthermore, pregnancy after treatment remains high risk with complications including spontaneous abortion, preterm delivery, intrauterine growth restriction, placenta accrete or praevia, or even uterine rupture.
Conclusion(s):
The management of moderate to severe disease still poses a challenge, and the prognosis of severe disease remains poor. Close antenatal surveillance and monitoring are necessary for women who conceive after treatment.
| Item Type: | Article |
|---|---|
| Additional Information: | PMID: 18406834 [PubMed - indexed for MEDLINE] |
| ISSNs: | 0015-0282 (print) |
| Related URLs: | |
| Keywords: | Intrauterine adhesion, asherman syndrome, hysteroscopic adhesiolysis, infertility, synechia, hysteroscopy, amenorrhea |
| Subjects: | R Medicine > RG Gynecology and obstetrics |
| Divisions: | University Structure - Pre August 2011 > School of Medicine > Developmental Origins of Health and Disease |
| Item ID: | 76224 |
| Date Deposited: | 15 Mar 2010 |
| Last Modified: | 22 Jul 2012 03:09 |
| Contributors: | Yu, Dan (Author) Wong, Yat-May (Author) Cheong, Ying (Author) Xia, Enlan (Author) Li, Tin-Chiu (Author) |
| Date: | April 2008 |
| Additional Information: | PMID: 18406834 [PubMed - indexed for MEDLINE] |
| Status: | Published |
| Contact Email Address: | Y.Cheong@soton.ac.uk |
| URI: | http://eprints.soton.ac.uk/id/eprint/76224 |
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