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Pushing back the frontiers of resectability in liver cancer surgery

Pushing back the frontiers of resectability in liver cancer surgery
Pushing back the frontiers of resectability in liver cancer surgery
Thanks to advances in surgical technique, anaesthesia and peri-operative care, hepatic resection has evolved from a rare procedure with an associated mortality rate of up to 20% to a routine surgery carried out in high volume liver units with an operative risk of less than 5%. This review concentrates on the techniques employed in radical hepatic resection, considering in particular: (1) The feasibility of extended hepatic parenchymal resections; (2) The treatment of lesions compromising the hepatic in-flow; and (3) The treatment of lesions compromising the hepatic out-flow. We discuss how these aims can be achieved by: minimizing the blood loss; minimizing the remnant liver parenchymal injury; performing an adequate oncological resection; and creating adequate venous out-flow reconstruction, using case series and case histories to illustrate these points.
hepatic resection
0748-7983
272-80
Abu Hilal, M.
384e1c60-8519-4eed-8e92-91775aad4c47
Lodge, J.P.A.
b121e863-35c1-41da-bf94-8c268144b023
Abu Hilal, M.
384e1c60-8519-4eed-8e92-91775aad4c47
Lodge, J.P.A.
b121e863-35c1-41da-bf94-8c268144b023

Abu Hilal, M. and Lodge, J.P.A. (2008) Pushing back the frontiers of resectability in liver cancer surgery. European Journal of Surgical Oncology, 34 (3), 272-80. (doi:10.1016/j.ejso.2007.07.201). (PMID:17949941)

Record type: Article

Abstract

Thanks to advances in surgical technique, anaesthesia and peri-operative care, hepatic resection has evolved from a rare procedure with an associated mortality rate of up to 20% to a routine surgery carried out in high volume liver units with an operative risk of less than 5%. This review concentrates on the techniques employed in radical hepatic resection, considering in particular: (1) The feasibility of extended hepatic parenchymal resections; (2) The treatment of lesions compromising the hepatic in-flow; and (3) The treatment of lesions compromising the hepatic out-flow. We discuss how these aims can be achieved by: minimizing the blood loss; minimizing the remnant liver parenchymal injury; performing an adequate oncological resection; and creating adequate venous out-flow reconstruction, using case series and case histories to illustrate these points.

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Published date: March 2008
Keywords: hepatic resection

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Local EPrints ID: 172251
URI: http://eprints.soton.ac.uk/id/eprint/172251
ISSN: 0748-7983
PURE UUID: d2bbc175-cfd7-4398-be0f-5df382fc2d39

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Date deposited: 25 Jan 2011 09:24
Last modified: 14 Mar 2024 02:28

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Contributors

Author: M. Abu Hilal
Author: J.P.A. Lodge

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