The University of Southampton
University of Southampton Institutional Repository

Solid-phase synthesis of cyclic sulfonamides employing a ring-closing metathesis-cleavage strategy

Solid-phase synthesis of cyclic sulfonamides employing a ring-closing metathesis-cleavage strategy
Solid-phase synthesis of cyclic sulfonamides employing a ring-closing metathesis-cleavage strategy
Ring-closing olefin metathesis using the Grubbs catalyst was applied to the cyclisative release of resin-bound sulfonamides. Flexible linkers apparently facilitated the cyclisation-leavage, allowing a number of novel cyclic sulfonamides to be prepared in good yields using catalytic amounts of the Grubbs catalyst.
ring-closing metathesis, solid-phase synthesis, sulfonamides, linkers organic-synthesis, olefin metathesis, support, oligosaccharides, heterocycles, cyclization
0040-4039
3681-3685
Brown, R. C. D.
fd92f80c-255a-4e51-861a-5ee85835bfcf
Castro, J. L.
2a394157-ea90-4236-97aa-e8f2b72c0a90
Moriggi, J. D.
a6ade426-cb79-48d7-90f3-4a55795d0b77
Brown, R. C. D.
fd92f80c-255a-4e51-861a-5ee85835bfcf
Castro, J. L.
2a394157-ea90-4236-97aa-e8f2b72c0a90
Moriggi, J. D.
a6ade426-cb79-48d7-90f3-4a55795d0b77

Brown, R. C. D., Castro, J. L. and Moriggi, J. D. (2000) Solid-phase synthesis of cyclic sulfonamides employing a ring-closing metathesis-cleavage strategy. Tetrahedron Letters, 41 (19), 3681-3685. (doi:10.1016/S0040-4039(00)00442-1).

Record type: Article

Abstract

Ring-closing olefin metathesis using the Grubbs catalyst was applied to the cyclisative release of resin-bound sulfonamides. Flexible linkers apparently facilitated the cyclisation-leavage, allowing a number of novel cyclic sulfonamides to be prepared in good yields using catalytic amounts of the Grubbs catalyst.

This record has no associated files available for download.

More information

Published date: 6 May 2000
Keywords: ring-closing metathesis, solid-phase synthesis, sulfonamides, linkers organic-synthesis, olefin metathesis, support, oligosaccharides, heterocycles, cyclization

Identifiers

Local EPrints ID: 18909
URI: http://eprints.soton.ac.uk/id/eprint/18909
ISSN: 0040-4039
PURE UUID: 64adae4b-dd7f-4e01-b17c-de2cb38df3e7

Catalogue record

Date deposited: 15 Dec 2005
Last modified: 15 Mar 2024 06:09

Export record

Altmetrics

Contributors

Author: R. C. D. Brown
Author: J. L. Castro
Author: J. D. Moriggi

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×