Aging, sarcopenia and the life course
Aging, sarcopenia and the life course
There is growing support for characterizing human aging from a life-course perspective, in terms of recognizing important influences operating from conception to death, and this approach provides a framework for understanding aging processes operating at the individual level. Kirkwood's disposable soma theory proposes that aging is a manifestation of imperfect somatic maintenance and repair processes. We can therefore predict that differing exposure to the determinants of somatic damage across the life-course, and variable capacity to respond in terms of repair are likely to underlie the wide variation in rates of aging between individuals.
265-274
Sayer, Avan Aihie
fb4c2053-6d51-4fc1-9489-c3cb431b0ffb
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
2007
Sayer, Avan Aihie
fb4c2053-6d51-4fc1-9489-c3cb431b0ffb
Cooper, Cyrus
e05f5612-b493-4273-9b71-9e0ce32bdad6
Sayer, Avan Aihie and Cooper, Cyrus
(2007)
Aging, sarcopenia and the life course.
Reviews in Clinical Gerontology, 16 (4), .
(doi:10.1017/S0959259807002225).
Abstract
There is growing support for characterizing human aging from a life-course perspective, in terms of recognizing important influences operating from conception to death, and this approach provides a framework for understanding aging processes operating at the individual level. Kirkwood's disposable soma theory proposes that aging is a manifestation of imperfect somatic maintenance and repair processes. We can therefore predict that differing exposure to the determinants of somatic damage across the life-course, and variable capacity to respond in terms of repair are likely to underlie the wide variation in rates of aging between individuals.
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Published date: 2007
Organisations:
Faculty of Medicine
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Local EPrints ID: 199457
URI: http://eprints.soton.ac.uk/id/eprint/199457
ISSN: 0959-2598
PURE UUID: 35dc39b8-6779-4cd5-9a04-dba23b4970e1
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Date deposited: 14 Oct 2011 13:34
Last modified: 18 Mar 2024 02:45
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Author:
Avan Aihie Sayer
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