The demonstration of an enhanced microelectrochemical transistor for measurements in neutral solution at low analyte concentration
The demonstration of an enhanced microelectrochemical transistor for measurements in neutral solution at low analyte concentration
We report a new, sensitive detection method for the measurement of analytes based on the combination of conducting polymer technology and redox enzyme electrochemistry. This method provides a simple measurement method potentially enabling point of care testing on disposable electrodes in under 60 s. The measurement does not require a reference or counter electrode and the analytical signal is recorded by an ammeter measuring milliampere currents through a polymer transistor. Even at very low analyte concentration, the signal is not subject to significant noise.
microelectrochemical transistor, neutral solution, analyte
alkaline-phosphatase, enzyme switch, chemical derivatization, aminophenyl phosphate, electronic devices, composite films, conductivity, fabrication, polyaniline, poly(3-methylthiophene
15-22
Astier, Y.
71e0ed8d-71bc-42e9-9225-398248c568bf
Bartlett, P.N.
d99446db-a59d-4f89-96eb-f64b5d8bb075
1 August 2004
Astier, Y.
71e0ed8d-71bc-42e9-9225-398248c568bf
Bartlett, P.N.
d99446db-a59d-4f89-96eb-f64b5d8bb075
Astier, Y. and Bartlett, P.N.
(2004)
The demonstration of an enhanced microelectrochemical transistor for measurements in neutral solution at low analyte concentration.
Bioelectrochemistry, 64 (1), .
(doi:10.1016/j.bioelechem.2003.12.008).
Abstract
We report a new, sensitive detection method for the measurement of analytes based on the combination of conducting polymer technology and redox enzyme electrochemistry. This method provides a simple measurement method potentially enabling point of care testing on disposable electrodes in under 60 s. The measurement does not require a reference or counter electrode and the analytical signal is recorded by an ammeter measuring milliampere currents through a polymer transistor. Even at very low analyte concentration, the signal is not subject to significant noise.
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Published date: 1 August 2004
Keywords:
microelectrochemical transistor, neutral solution, analyte
alkaline-phosphatase, enzyme switch, chemical derivatization, aminophenyl phosphate, electronic devices, composite films, conductivity, fabrication, polyaniline, poly(3-methylthiophene
Identifiers
Local EPrints ID: 20121
URI: http://eprints.soton.ac.uk/id/eprint/20121
PURE UUID: b0708ac1-a213-43cc-8076-3a35c6eb68f0
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Date deposited: 23 Feb 2006
Last modified: 16 Mar 2024 02:42
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Author:
Y. Astier
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