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Case report of an arterioportal fistula, presenting with accelerated decompensation and sepsis, twenty-six years after initial liver biopsy

Case report of an arterioportal fistula, presenting with accelerated decompensation and sepsis, twenty-six years after initial liver biopsy
Case report of an arterioportal fistula, presenting with accelerated decompensation and sepsis, twenty-six years after initial liver biopsy
We describe the case of a 55-year-old lady who presented with accelerated hepatic decompensation from an arterioportal fistula (APF). There is histological evidence the APF proceeded a percutaneous liver biopsy performed 26 years ago. She had shown no symptoms or signs of liver disease in the intervening period.
The clinical presentation initially was that of portal hypertension but evolved into a systemic inflammatory response syndrome associated with renal and liver failure. We describe how the APF was embolised by interventional radiology and how the timing of this decision was a balance between reversing abnormal haemodynamics and trying to avoid instrumentation of a potentially septic environment. This unusual case reflects the relationship between portal hypertension, sepsis and renal failure.
arterioportal fistula, embolisation, portal hypertension, systemic inflammatory response syndrome
1386-6346
252-255
Guha, I.N.
15ece18d-5a89-4c6d-9c85-9df96dd022e1
Stedman, B.
58aa88de-d498-4f8b-8d91-83545f28c7e5
Iredale, J.P.
5c8dbd67-954f-4a50-b084-af1d253277cb
Sheron, N.
cbf852e3-cfaa-43b2-ab99-a954d96069f1
Guha, I.N.
15ece18d-5a89-4c6d-9c85-9df96dd022e1
Stedman, B.
58aa88de-d498-4f8b-8d91-83545f28c7e5
Iredale, J.P.
5c8dbd67-954f-4a50-b084-af1d253277cb
Sheron, N.
cbf852e3-cfaa-43b2-ab99-a954d96069f1

Guha, I.N., Stedman, B., Iredale, J.P. and Sheron, N. (2005) Case report of an arterioportal fistula, presenting with accelerated decompensation and sepsis, twenty-six years after initial liver biopsy. Hepatology Research, 32 (4), 252-255. (doi:10.1016/j.hepres.2005.05.006).

Record type: Article

Abstract

We describe the case of a 55-year-old lady who presented with accelerated hepatic decompensation from an arterioportal fistula (APF). There is histological evidence the APF proceeded a percutaneous liver biopsy performed 26 years ago. She had shown no symptoms or signs of liver disease in the intervening period.
The clinical presentation initially was that of portal hypertension but evolved into a systemic inflammatory response syndrome associated with renal and liver failure. We describe how the APF was embolised by interventional radiology and how the timing of this decision was a balance between reversing abnormal haemodynamics and trying to avoid instrumentation of a potentially septic environment. This unusual case reflects the relationship between portal hypertension, sepsis and renal failure.

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More information

Published date: 2005
Keywords: arterioportal fistula, embolisation, portal hypertension, systemic inflammatory response syndrome

Identifiers

Local EPrints ID: 27078
URI: http://eprints.soton.ac.uk/id/eprint/27078
ISSN: 1386-6346
PURE UUID: 6b052f4f-3e1e-401b-b765-8b1e59a2cf7e
ORCID for N. Sheron: ORCID iD orcid.org/0000-0001-5232-8292

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Date deposited: 26 Apr 2006
Last modified: 15 Mar 2024 07:15

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Contributors

Author: I.N. Guha
Author: B. Stedman
Author: J.P. Iredale
Author: N. Sheron ORCID iD

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