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Towards molecular computing: co-development of microfluidic devices and chemical reaction media

Towards molecular computing: co-development of microfluidic devices and chemical reaction media
Towards molecular computing: co-development of microfluidic devices and chemical reaction media
Microfluidics provides a powerful technology for both the production of molecular computing components and for the implementation of molecular computing architectures. The potential commercial applications of microfluidics drive rapid progress in this field—but at the same time focus interest on materials that are compatible with physiological aqueous conditions. For engineering applications that consider a broader range of physico-chemical conditions the narrow set of established materials for microfluidics can be a challenge. As a consequence of the large surface to volume ratio inherent in microfluidic technology the material of the device can greatly affect the chemistry in the channels of the device. In practice it is necessary to co-develop the chemical medium to be used in the device together with the microfluidic devices. We describe this process for a molecular computing architecture that makes use of excitable lipid-coated droplets of Belousov–Zhabotinsky reaction medium as its active processing components. We identify fluoropolymers with low melting temperature as a suitable substrate for microfluidics to be used in conjunction with Belousov–Zhabotinsky droplets in decane.

0303-2647
18-23
King, Philip
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Corsi, Josephine C.
5ff440af-f469-4352-883c-fa6926d8ee2c
Pan, Ben-Hong
51420dae-f77b-4a35-9025-b8955f1a823d
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
de Planque, Maurits R.R.
a1d33d13-f516-44fb-8d2c-c51d18bc21ba
Zauner, Klaus-Peter
c8b22dbd-10e6-43d8-813b-0766f985cc97
King, Philip
3a0f2b7e-b08a-46b2-abef-89be45c2a7d5
Corsi, Josephine C.
5ff440af-f469-4352-883c-fa6926d8ee2c
Pan, Ben-Hong
51420dae-f77b-4a35-9025-b8955f1a823d
Morgan, Hywel
de00d59f-a5a2-48c4-a99a-1d5dd7854174
de Planque, Maurits R.R.
a1d33d13-f516-44fb-8d2c-c51d18bc21ba
Zauner, Klaus-Peter
c8b22dbd-10e6-43d8-813b-0766f985cc97

King, Philip, Corsi, Josephine C., Pan, Ben-Hong, Morgan, Hywel, de Planque, Maurits R.R. and Zauner, Klaus-Peter (2012) Towards molecular computing: co-development of microfluidic devices and chemical reaction media. Biosystems, 109 (1), 18-23. (doi:10.1016/j.biosystems.2012.01.003).

Record type: Article

Abstract

Microfluidics provides a powerful technology for both the production of molecular computing components and for the implementation of molecular computing architectures. The potential commercial applications of microfluidics drive rapid progress in this field—but at the same time focus interest on materials that are compatible with physiological aqueous conditions. For engineering applications that consider a broader range of physico-chemical conditions the narrow set of established materials for microfluidics can be a challenge. As a consequence of the large surface to volume ratio inherent in microfluidic technology the material of the device can greatly affect the chemistry in the channels of the device. In practice it is necessary to co-develop the chemical medium to be used in the device together with the microfluidic devices. We describe this process for a molecular computing architecture that makes use of excitable lipid-coated droplets of Belousov–Zhabotinsky reaction medium as its active processing components. We identify fluoropolymers with low melting temperature as a suitable substrate for microfluidics to be used in conjunction with Belousov–Zhabotinsky droplets in decane.

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Accepted/In Press date: 4 January 2012
Published date: 9 June 2012
Organisations: Nanoelectronics and Nanotechnology, Agents, Interactions & Complexity

Identifiers

Local EPrints ID: 273062
URI: http://eprints.soton.ac.uk/id/eprint/273062
ISSN: 0303-2647
PURE UUID: 28a6185e-b2b4-4db2-b304-060500e1ceb0
ORCID for Hywel Morgan: ORCID iD orcid.org/0000-0003-4850-5676
ORCID for Maurits R.R. de Planque: ORCID iD orcid.org/0000-0002-8787-0513

Catalogue record

Date deposited: 13 Dec 2011 09:58
Last modified: 15 Mar 2024 03:18

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Contributors

Author: Philip King
Author: Josephine C. Corsi
Author: Ben-Hong Pan
Author: Hywel Morgan ORCID iD
Author: Maurits R.R. de Planque ORCID iD
Author: Klaus-Peter Zauner

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