Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia
Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia
This study demonstrates the feasibility and safety of conducting a large healthy volunteer cohort study of human adaptation to hypoxia in this difficult environment. Systematic measurements of a large set of variables were achieved in 222 subjects and at altitudes up to 8400 m. The resulting dataset is a unique resource for the study of genotype:phenotype interactions in relation to hypoxic adaptation.
98
Levett, Denny Z.H.
4b33b751-32be-4fa3-aaf7-b62e62f08de8
Martin, Daniel S.
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Wilson, Mark H.
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Mitchell, Kay
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Dhillon, Sundeep
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Rigat, Fabio
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Montgomery, Hugh E.
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Mythen, Monty G.
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Grocott, Michael P.W.
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Caduwell Xtreme Everest Research Group
21 October 2010
Levett, Denny Z.H.
4b33b751-32be-4fa3-aaf7-b62e62f08de8
Martin, Daniel S.
3e441b48-9221-4308-8ae6-49cbde20753f
Wilson, Mark H.
9a48b1f2-494b-42cf-a02c-c0a0e9967d33
Mitchell, Kay
f57f07cd-0e3a-48b2-a871-c436eec325ae
Dhillon, Sundeep
00137d3e-4cb6-4463-b1b9-33517d5e3e3f
Rigat, Fabio
b226a1af-9968-464d-a47a-85025cae4736
Montgomery, Hugh E.
8082956e-3142-42b4-9f46-b0c9cee79785
Mythen, Monty G.
266ffcca-f8dd-49b4-abe4-0ffb035e2b35
Grocott, Michael P.W.
1e87b741-513e-4a22-be13-0f7bb344e8c2
Levett, Denny Z.H., Martin, Daniel S., Wilson, Mark H., Mitchell, Kay, Dhillon, Sundeep, Rigat, Fabio, Montgomery, Hugh E., Mythen, Monty G. and Grocott, Michael P.W.
,
Caduwell Xtreme Everest Research Group
(2010)
Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia.
BMC Medical Research Methodology, 10, .
(doi:10.1186/1471-2288-10-98).
(PMID:20964858)
Abstract
This study demonstrates the feasibility and safety of conducting a large healthy volunteer cohort study of human adaptation to hypoxia in this difficult environment. Systematic measurements of a large set of variables were achieved in 222 subjects and at altitudes up to 8400 m. The resulting dataset is a unique resource for the study of genotype:phenotype interactions in relation to hypoxic adaptation.
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Published date: 21 October 2010
Organisations:
Human Development & Health
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Local EPrints ID: 348891
URI: http://eprints.soton.ac.uk/id/eprint/348891
ISSN: 1471-2288
PURE UUID: 038341b1-d7ae-4f8e-bc2a-4eae6ac74b1c
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Date deposited: 25 Feb 2013 10:21
Last modified: 15 Mar 2024 04:02
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Contributors
Author:
Denny Z.H. Levett
Author:
Daniel S. Martin
Author:
Mark H. Wilson
Author:
Kay Mitchell
Author:
Sundeep Dhillon
Author:
Fabio Rigat
Author:
Hugh E. Montgomery
Author:
Monty G. Mythen
Corporate Author: Caduwell Xtreme Everest Research Group
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