Nanoscale Ion mediated networks in bone: osteopontin can repeatedly dissipate large amounts of energy
Nanoscale Ion mediated networks in bone: osteopontin can repeatedly dissipate large amounts of energy
In the nanocomposite bone, inorganic material is combined with several types of organic molecules, and these complexes have been proposed to increase the bone strength. Here we report on a mechanism of how one of these components, human osteopontin, forms large mechanical networks that can repeatedly dissipate energy through work against entropy by breaking sacrificial bonds and stretching hidden length. The behavior of these in vitro networks is similar to that of organic components in bone, acting as an adhesive layer in between mineralized fibrils.
2491-2498
Fantner, Georg E.
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Adams, Jonathan
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Turner, Patricia
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Thurner, Philipp J.
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Fisher, Larry W.
29d572f7-f0df-42a4-8a71-01a44d4ba9a5
Hansma, Paul K.
aeab95c4-0f23-4690-8302-72db3316215d
July 2007
Fantner, Georg E.
e95e5469-568d-4c76-843c-bb8a4f6153df
Adams, Jonathan
60c7d6a7-9c02-4f4d-acec-3fcb54eec843
Turner, Patricia
fb040b75-606d-4dba-b4f7-1e00a4d348ed
Thurner, Philipp J.
ab711ddd-784e-48de-aaad-f56aec40f84f
Fisher, Larry W.
29d572f7-f0df-42a4-8a71-01a44d4ba9a5
Hansma, Paul K.
aeab95c4-0f23-4690-8302-72db3316215d
Fantner, Georg E., Adams, Jonathan, Turner, Patricia, Thurner, Philipp J., Fisher, Larry W. and Hansma, Paul K.
(2007)
Nanoscale Ion mediated networks in bone: osteopontin can repeatedly dissipate large amounts of energy.
Nano Letters, 7 (8), .
(doi:10.1021/nl0712769).
Abstract
In the nanocomposite bone, inorganic material is combined with several types of organic molecules, and these complexes have been proposed to increase the bone strength. Here we report on a mechanism of how one of these components, human osteopontin, forms large mechanical networks that can repeatedly dissipate energy through work against entropy by breaking sacrificial bonds and stretching hidden length. The behavior of these in vitro networks is similar to that of organic components in bone, acting as an adhesive layer in between mineralized fibrils.
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Published date: July 2007
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Local EPrints ID: 48335
URI: http://eprints.soton.ac.uk/id/eprint/48335
ISSN: 1530-6984
PURE UUID: 0e794aed-5ea2-4188-958b-5447df7f7e72
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Date deposited: 13 Sep 2007
Last modified: 15 Mar 2024 09:45
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Contributors
Author:
Georg E. Fantner
Author:
Jonathan Adams
Author:
Patricia Turner
Author:
Larry W. Fisher
Author:
Paul K. Hansma
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