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Development of a new diagnostic sensor for extra-corporeal shock-wave lithotripsy

Development of a new diagnostic sensor for extra-corporeal shock-wave lithotripsy
Development of a new diagnostic sensor for extra-corporeal shock-wave lithotripsy
Extracorporeal shock-wave lithotripsy is the leading technique used in urology for the non-invasive treatment of kidney and ureteric stones. The stone is comminuted by thousands of ultrasound shocks, into fragments small enough to be naturally passed. Since the technique was introduced in the 1980 different generations of lithotripters have been developed. Nevertheless the alignment systems (x-ray, ultrasound) still have some limitations (indeed, the tighter focusing of newer lithotripter reduces the tolerance for misalignment) and there is no capability for on-line monitoring of the degree of fragmentation of the stone. There is 50% incidence of re-treatments, possibly due to these deficiencies. The objective of this research is to design a new passive acoustic sensor, exploiting the secondary acoustic emission generated during the treatment, which could be used as a diagnostic device for lithotripsy. With a passive cylindrical cavitation detector, developed by the National Physical Laboratory, it was possible to detect these emissions in a laboratory lithotripter, and it was shown that they contain information on the degree of stone fragmentation and stone location. This information could be used to perform the desired monitoring and to improve the stone targeting. In collaboration with Precision Acoustic Ltd, some clinical prototypes were developed and tested to verify the relevance of these preliminary results. Clinical results are presented.
1742-6588
134-139
Fedele, F.
5388869a-313f-4069-a2e9-69cd832c68ca
Coleman, A.J.
1c05afe0-16b8-4547-98fb-93ed8872ea0e
Leighton, T.G.
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
White, P.R.
2dd2477b-5aa9-42e2-9d19-0806d994eaba
Hurrell, A.M.
f4555c9f-a7fd-4b90-965d-a10a640fd780
Fedele, F.
5388869a-313f-4069-a2e9-69cd832c68ca
Coleman, A.J.
1c05afe0-16b8-4547-98fb-93ed8872ea0e
Leighton, T.G.
3e5262ce-1d7d-42eb-b013-fcc5c286bbae
White, P.R.
2dd2477b-5aa9-42e2-9d19-0806d994eaba
Hurrell, A.M.
f4555c9f-a7fd-4b90-965d-a10a640fd780

Fedele, F., Coleman, A.J., Leighton, T.G., White, P.R. and Hurrell, A.M. (2004) Development of a new diagnostic sensor for extra-corporeal shock-wave lithotripsy. Journal of Physics: Conference Series, 1, 134-139. (doi:10.1088/1742-6596/1/1/031).

Record type: Article

Abstract

Extracorporeal shock-wave lithotripsy is the leading technique used in urology for the non-invasive treatment of kidney and ureteric stones. The stone is comminuted by thousands of ultrasound shocks, into fragments small enough to be naturally passed. Since the technique was introduced in the 1980 different generations of lithotripters have been developed. Nevertheless the alignment systems (x-ray, ultrasound) still have some limitations (indeed, the tighter focusing of newer lithotripter reduces the tolerance for misalignment) and there is no capability for on-line monitoring of the degree of fragmentation of the stone. There is 50% incidence of re-treatments, possibly due to these deficiencies. The objective of this research is to design a new passive acoustic sensor, exploiting the secondary acoustic emission generated during the treatment, which could be used as a diagnostic device for lithotripsy. With a passive cylindrical cavitation detector, developed by the National Physical Laboratory, it was possible to detect these emissions in a laboratory lithotripter, and it was shown that they contain information on the degree of stone fragmentation and stone location. This information could be used to perform the desired monitoring and to improve the stone targeting. In collaboration with Precision Acoustic Ltd, some clinical prototypes were developed and tested to verify the relevance of these preliminary results. Clinical results are presented.

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Published date: 2004

Identifiers

Local EPrints ID: 49582
URI: http://eprints.soton.ac.uk/id/eprint/49582
ISSN: 1742-6588
PURE UUID: c00aa2a8-cfc7-4df3-9338-0b7a4b1949d0
ORCID for T.G. Leighton: ORCID iD orcid.org/0000-0002-1649-8750
ORCID for P.R. White: ORCID iD orcid.org/0000-0002-4787-8713

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Date deposited: 20 Nov 2007
Last modified: 16 Mar 2024 02:44

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Contributors

Author: F. Fedele
Author: A.J. Coleman
Author: T.G. Leighton ORCID iD
Author: P.R. White ORCID iD
Author: A.M. Hurrell

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