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Deep brain stimulation: a new treatment for hypertension?

Deep brain stimulation: a new treatment for hypertension?
Deep brain stimulation: a new treatment for hypertension?
We report a 61-year-old hypertensive man who underwent deep brain stimulation of the periventricular/periaqueductal grey area for the relief of chronic neuropathic pain affecting his oral cavity and soft palate. During intraoperative stimulation, we were able to modulate his blood pressure up or down, depending on electrode location. This is the first evidence that hypertension could be effectively treated with electrical stimulation of the midbrain.
blood pressure, deep brain stimulation, periaqueductal grey, hypertension
0967-5868
592-595
Green, A.L.
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Wang, S.
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Bittar, R.G.
398d329d-2830-44f9-8e06-5e868e226dd4
Owen, S.L.F.
7442b120-e060-41f4-bdba-54ea68106f5f
Paterson, D.J.
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Stein, J.F.
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Bain, P.G.
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Shlugman, D.
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Aziz, T.Z.
728d8821-5fa0-407f-a09f-5a52038ad170
Green, A.L.
d7df7b1a-1a56-495a-b93e-6d8211279e29
Wang, S.
8bce5bdb-420c-4b22-b009-8f4ce1febaa8
Bittar, R.G.
398d329d-2830-44f9-8e06-5e868e226dd4
Owen, S.L.F.
7442b120-e060-41f4-bdba-54ea68106f5f
Paterson, D.J.
490e44cd-f70c-4171-9441-a64c9c830c5f
Stein, J.F.
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Bain, P.G.
6f63e03e-9273-426e-adc0-72eb1bec9e63
Shlugman, D.
90294b23-3a8c-40c7-86a5-1ab829c720c1
Aziz, T.Z.
728d8821-5fa0-407f-a09f-5a52038ad170

Green, A.L., Wang, S., Bittar, R.G., Owen, S.L.F., Paterson, D.J., Stein, J.F., Bain, P.G., Shlugman, D. and Aziz, T.Z. (2007) Deep brain stimulation: a new treatment for hypertension? Journal of Clinical Neuroscience, 14 (6), 592-595. (doi:10.1016/j.jocn.2006.04.015).

Record type: Article

Abstract

We report a 61-year-old hypertensive man who underwent deep brain stimulation of the periventricular/periaqueductal grey area for the relief of chronic neuropathic pain affecting his oral cavity and soft palate. During intraoperative stimulation, we were able to modulate his blood pressure up or down, depending on electrode location. This is the first evidence that hypertension could be effectively treated with electrical stimulation of the midbrain.

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More information

Published date: June 2007
Keywords: blood pressure, deep brain stimulation, periaqueductal grey, hypertension
Organisations: Human Sciences Group

Identifiers

Local EPrints ID: 49591
URI: http://eprints.soton.ac.uk/id/eprint/49591
ISSN: 0967-5868
PURE UUID: 56ffeb71-c8c2-4111-9f19-37d7c9af29f5

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Date deposited: 19 Nov 2007
Last modified: 15 Mar 2024 09:57

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Contributors

Author: A.L. Green
Author: S. Wang
Author: R.G. Bittar
Author: S.L.F. Owen
Author: D.J. Paterson
Author: J.F. Stein
Author: P.G. Bain
Author: D. Shlugman
Author: T.Z. Aziz

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