The University of Southampton
University of Southampton Institutional Repository

On the highly stereoselective addition of lithio-acetylides to alpha-hydroxy-ketones

On the highly stereoselective addition of lithio-acetylides to alpha-hydroxy-ketones
On the highly stereoselective addition of lithio-acetylides to alpha-hydroxy-ketones
Addition of 2 equiv of a lithio-acetylide to an unprotected ?-hydroxy ketone is extremely stereoselective in examples where the two ketone substituents are relatively large.
5-endo-dig cyclizations, beta-iodofurans
0040-4039
2240-2242
Dunford, D.
378dc511-3641-43a7-8a8d-449545c8c56d
Guyader, M.
c3a54c84-c54b-4399-8894-d72f2e51abd9
Jones, S.
43516f9c-c999-4c10-86b6-43992e4e7a29
Knight, D.W.
dbe05fb8-fea1-4e2e-8555-0c72c3f5bc65
Hursthouse, M.B.
57a2ddf9-b1b3-4f38-bfe9-ef2f526388da
Coles, S.J.
3116f58b-c30c-48cf-bdd5-397d1c1fecf8
Dunford, D.
378dc511-3641-43a7-8a8d-449545c8c56d
Guyader, M.
c3a54c84-c54b-4399-8894-d72f2e51abd9
Jones, S.
43516f9c-c999-4c10-86b6-43992e4e7a29
Knight, D.W.
dbe05fb8-fea1-4e2e-8555-0c72c3f5bc65
Hursthouse, M.B.
57a2ddf9-b1b3-4f38-bfe9-ef2f526388da
Coles, S.J.
3116f58b-c30c-48cf-bdd5-397d1c1fecf8

Dunford, D., Guyader, M., Jones, S., Knight, D.W., Hursthouse, M.B. and Coles, S.J. (2008) On the highly stereoselective addition of lithio-acetylides to alpha-hydroxy-ketones. Tetrahedron Letters, 49 (14), 2240-2242. (doi:10.1016/j.tetlet.2008.02.032).

Record type: Article

Abstract

Addition of 2 equiv of a lithio-acetylide to an unprotected ?-hydroxy ketone is extremely stereoselective in examples where the two ketone substituents are relatively large.

This record has no associated files available for download.

More information

Published date: 31 March 2008
Keywords: 5-endo-dig cyclizations, beta-iodofurans

Identifiers

Local EPrints ID: 54445
URI: http://eprints.soton.ac.uk/id/eprint/54445
ISSN: 0040-4039
PURE UUID: dfbf8123-b902-44c2-a035-ae3b1a999b1e
ORCID for S.J. Coles: ORCID iD orcid.org/0000-0001-8414-9272

Catalogue record

Date deposited: 05 Aug 2008
Last modified: 16 Mar 2024 03:05

Export record

Altmetrics

Contributors

Author: D. Dunford
Author: M. Guyader
Author: S. Jones
Author: D.W. Knight
Author: M.B. Hursthouse
Author: S.J. Coles ORCID iD

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×