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A systematic review of the use and validation of health-related quality of life instruments in older cancer patients

A systematic review of the use and validation of health-related quality of life instruments in older cancer patients
A systematic review of the use and validation of health-related quality of life instruments in older cancer patients
AIM: The aim of this paper is to systematically review the use and validation of HRQOL instruments in older cancer patients.

METHOD: A systematic review of 5 databases and 3 research registers identified studies reporting the use and validation of HRQOL instruments in cancer patients aged over 65 years from 1995 to mid 2007.

RESULTS: Thirty-one studies reported the use of HRQOL measures in older people, using a range of generic and disease-specific instruments. Little work was reported in patients aged over 80 years. All studies exhibited methodological limitations. Fourteen studies were identified with variable evidence on the psychometric properties and clinical usefulness of identified instruments.

CONCLUSION: Our review identified that the development, validation and use of HRQOL instruments often ignore the specific needs of older people. This review highlights the need for a HRQOL instrument specifically designed to capture the issues and concerns most relevant to older cancer patients.
quality of life, review, quality-of-life, cancer, patients
0959-8049
19-32
Fitzsimmons, Deborah
4e282651-162f-48f0-bbf7-190c265279f2
Gilbert, Jaqueline
deece296-b1ae-4a3f-bcf2-a3c97cd5d5cb
Howse, Frances
83c7d405-14bb-4947-bd9f-1fbb8849c488
Young, Teresa
0fc82d81-c178-4a81-89d8-6a5cc2e52627
Arrarras, Juan-Ignacio
b63f6aab-49da-4882-93d5-547315eb8109
Brédart, Anne
9a1c6419-316a-43ff-b47c-3af649c50438
Hawker, Sheila
0e7539f9-9b7c-4757-bc7c-86ebd97b35e2
George, Steve
bdfc752b-f67e-4490-8dc0-99bfaeb046ca
Aapro, Matti
d0725643-bf70-473c-afc1-a76ac5a70bf7
Johnson, Colin D.
e50aa9cd-8c61-4fe3-a0b3-f51cc3a6c74a
Fitzsimmons, Deborah
4e282651-162f-48f0-bbf7-190c265279f2
Gilbert, Jaqueline
deece296-b1ae-4a3f-bcf2-a3c97cd5d5cb
Howse, Frances
83c7d405-14bb-4947-bd9f-1fbb8849c488
Young, Teresa
0fc82d81-c178-4a81-89d8-6a5cc2e52627
Arrarras, Juan-Ignacio
b63f6aab-49da-4882-93d5-547315eb8109
Brédart, Anne
9a1c6419-316a-43ff-b47c-3af649c50438
Hawker, Sheila
0e7539f9-9b7c-4757-bc7c-86ebd97b35e2
George, Steve
bdfc752b-f67e-4490-8dc0-99bfaeb046ca
Aapro, Matti
d0725643-bf70-473c-afc1-a76ac5a70bf7
Johnson, Colin D.
e50aa9cd-8c61-4fe3-a0b3-f51cc3a6c74a

Fitzsimmons, Deborah, Gilbert, Jaqueline, Howse, Frances, Young, Teresa, Arrarras, Juan-Ignacio, Brédart, Anne, Hawker, Sheila, George, Steve, Aapro, Matti and Johnson, Colin D. (2009) A systematic review of the use and validation of health-related quality of life instruments in older cancer patients. European Journal of Cancer, 45 (1), 19-32. (doi:10.1016/j.ejca.2008.07.036).

Record type: Article

Abstract

AIM: The aim of this paper is to systematically review the use and validation of HRQOL instruments in older cancer patients.

METHOD: A systematic review of 5 databases and 3 research registers identified studies reporting the use and validation of HRQOL instruments in cancer patients aged over 65 years from 1995 to mid 2007.

RESULTS: Thirty-one studies reported the use of HRQOL measures in older people, using a range of generic and disease-specific instruments. Little work was reported in patients aged over 80 years. All studies exhibited methodological limitations. Fourteen studies were identified with variable evidence on the psychometric properties and clinical usefulness of identified instruments.

CONCLUSION: Our review identified that the development, validation and use of HRQOL instruments often ignore the specific needs of older people. This review highlights the need for a HRQOL instrument specifically designed to capture the issues and concerns most relevant to older cancer patients.

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More information

Published date: January 2009
Keywords: quality of life, review, quality-of-life, cancer, patients

Identifiers

Local EPrints ID: 61781
URI: http://eprints.soton.ac.uk/id/eprint/61781
ISSN: 0959-8049
PURE UUID: 1afb9c14-5d45-44b9-9f12-c49676200496

Catalogue record

Date deposited: 06 Oct 2008
Last modified: 15 Mar 2024 11:28

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Contributors

Author: Deborah Fitzsimmons
Author: Jaqueline Gilbert
Author: Frances Howse
Author: Teresa Young
Author: Juan-Ignacio Arrarras
Author: Anne Brédart
Author: Sheila Hawker
Author: Steve George
Author: Matti Aapro

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