The University of Southampton
University of Southampton Institutional Repository

The Global Longitudinal Study of Osteoporosis in Women (GLOW): rationale and study design

The Global Longitudinal Study of Osteoporosis in Women (GLOW): rationale and study design
The Global Longitudinal Study of Osteoporosis in Women (GLOW): rationale and study design
Summary: the Global Longitudinal study of Osteoporosis in Women (GLOW) is a prospective cohort study involving 723 physicians and 60,393 women subjects ?55 years. The data will provide insights into the management of fracture risk in older women over 5 years, patient experience with prevention and treatment, and distribution of risk among older women on an international basis. Introduction: data from cohort studies describing the distribution of osteoporosis-related fractures and risk factors are not directly comparable and do not compare regional differences in patterns of patient management and fracture outcomes. Methods: the GLOW is a prospective, multinational, observational cohort study. Practices typical of each region were identified through primary care networks organized for administrative, research, or educational purposes. Noninstitutionalized patients visiting each practice within the previous 2 years were eligible. Self-administered questionnaires were mailed, with 2:1 oversampling of women ?65 years. Follow-up questionnaires will be sent at 12-month intervals for 5 years. Results: a total of 723 physicians at 17 sites in ten countries agreed to participate. Baseline surveys were mailed (October 2006 to February 2008) to 140,416 subjects. After the exclusion of 3,265 women who were ineligible or had died, 60,393 agreed to participate. Conclusions: GLOW will provide contemporary information on patterns of management of fracture risk in older women over a 5-year period. The collection of data in a similar manner in ten countries will permit comparisons of patient experience with prevention and treatment and provide insights into the distribution of risk among older women on an international basis
fracture, osteoporosis, prevention, risk factors, treatments, women
0937-941X
1107-1116
Hooven, F.H.
f272e96b-89e1-4582-b587-6b1a4b188554
Adachi, J.D.
fad23249-519e-4d11-ac21-f42742cd19fb
Adami, S.
4e8b8772-f6ad-4ed6-8629-6ed35cd921fd
Boonen, S.
19c70ece-493f-4b7c-9bf9-5e4a4a887ba4
Compston, J.
b64c0d0e-97dd-44c8-97ba-f756f0bc966d
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Delmas, P.
6615b37c-223b-4e55-b573-3ccc1cb40ac4
Diez-Perez, A.
19f89c53-003a-469c-92ac-69b0b979f3ec
Gelhbach, S.
d1bf6214-1e08-4271-9fcf-188d823158e7
Greenspan, S.L.
69b09b9d-bff3-428b-b0cd-e746e1095159
LaCroix, A.
db973acd-4097-4be1-b397-1bee3f47604a
Lindsay, R.
cb19528e-f409-4285-89bd-5a29b1089da6
Netenlenbos, J.C.
d6fab476-6dcc-4700-ad66-9ba8af0e2c67
Pfeilschifter, J.
39a39944-567b-47d5-8973-630dcd32b2cc
Roux, C.
fc926270-4149-405d-8cce-44d9305cc45d
Saag, K.C.
461911e5-027c-48db-9fe1-a8a08f40cf81
Sambrook, P.
17fed862-0ad3-4bb9-8e6d-1474e8308da5
Silverman, S.
dfe0f214-17ef-41de-b403-7e2b3105f178
Siris, E.
34f296f5-0065-4bdd-9656-28db3a86b331
Watts, N.B.
c9df517c-166d-4ba1-8b9d-25947998a89f
Anderson Jr, F.A.
831b8aff-40c7-4d82-9404-673551d132e0
Hooven, F.H.
f272e96b-89e1-4582-b587-6b1a4b188554
Adachi, J.D.
fad23249-519e-4d11-ac21-f42742cd19fb
Adami, S.
4e8b8772-f6ad-4ed6-8629-6ed35cd921fd
Boonen, S.
19c70ece-493f-4b7c-9bf9-5e4a4a887ba4
Compston, J.
b64c0d0e-97dd-44c8-97ba-f756f0bc966d
Cooper, C.
e05f5612-b493-4273-9b71-9e0ce32bdad6
Delmas, P.
6615b37c-223b-4e55-b573-3ccc1cb40ac4
Diez-Perez, A.
19f89c53-003a-469c-92ac-69b0b979f3ec
Gelhbach, S.
d1bf6214-1e08-4271-9fcf-188d823158e7
Greenspan, S.L.
69b09b9d-bff3-428b-b0cd-e746e1095159
LaCroix, A.
db973acd-4097-4be1-b397-1bee3f47604a
Lindsay, R.
cb19528e-f409-4285-89bd-5a29b1089da6
Netenlenbos, J.C.
d6fab476-6dcc-4700-ad66-9ba8af0e2c67
Pfeilschifter, J.
39a39944-567b-47d5-8973-630dcd32b2cc
Roux, C.
fc926270-4149-405d-8cce-44d9305cc45d
Saag, K.C.
461911e5-027c-48db-9fe1-a8a08f40cf81
Sambrook, P.
17fed862-0ad3-4bb9-8e6d-1474e8308da5
Silverman, S.
dfe0f214-17ef-41de-b403-7e2b3105f178
Siris, E.
34f296f5-0065-4bdd-9656-28db3a86b331
Watts, N.B.
c9df517c-166d-4ba1-8b9d-25947998a89f
Anderson Jr, F.A.
831b8aff-40c7-4d82-9404-673551d132e0

Hooven, F.H., Adachi, J.D., Adami, S., Boonen, S., Compston, J., Cooper, C., Delmas, P., Diez-Perez, A., Gelhbach, S., Greenspan, S.L., LaCroix, A., Lindsay, R., Netenlenbos, J.C., Pfeilschifter, J., Roux, C., Saag, K.C., Sambrook, P., Silverman, S., Siris, E., Watts, N.B. and Anderson Jr, F.A. (2009) The Global Longitudinal Study of Osteoporosis in Women (GLOW): rationale and study design. Osteoporosis International, 20 (7), 1107-1116. (doi:10.1007/s00198-009-0958-2).

Record type: Article

Abstract

Summary: the Global Longitudinal study of Osteoporosis in Women (GLOW) is a prospective cohort study involving 723 physicians and 60,393 women subjects ?55 years. The data will provide insights into the management of fracture risk in older women over 5 years, patient experience with prevention and treatment, and distribution of risk among older women on an international basis. Introduction: data from cohort studies describing the distribution of osteoporosis-related fractures and risk factors are not directly comparable and do not compare regional differences in patterns of patient management and fracture outcomes. Methods: the GLOW is a prospective, multinational, observational cohort study. Practices typical of each region were identified through primary care networks organized for administrative, research, or educational purposes. Noninstitutionalized patients visiting each practice within the previous 2 years were eligible. Self-administered questionnaires were mailed, with 2:1 oversampling of women ?65 years. Follow-up questionnaires will be sent at 12-month intervals for 5 years. Results: a total of 723 physicians at 17 sites in ten countries agreed to participate. Baseline surveys were mailed (October 2006 to February 2008) to 140,416 subjects. After the exclusion of 3,265 women who were ineligible or had died, 60,393 agreed to participate. Conclusions: GLOW will provide contemporary information on patterns of management of fracture risk in older women over a 5-year period. The collection of data in a similar manner in ten countries will permit comparisons of patient experience with prevention and treatment and provide insights into the distribution of risk among older women on an international basis

This record has no associated files available for download.

More information

Published date: July 2009
Keywords: fracture, osteoporosis, prevention, risk factors, treatments, women

Identifiers

Local EPrints ID: 68871
URI: http://eprints.soton.ac.uk/id/eprint/68871
ISSN: 0937-941X
PURE UUID: 26b0fcbb-0413-4b5c-b7c6-737cf5dcee14
ORCID for C. Cooper: ORCID iD orcid.org/0000-0003-3510-0709

Catalogue record

Date deposited: 07 Oct 2009
Last modified: 18 Mar 2024 02:44

Export record

Altmetrics

Contributors

Author: F.H. Hooven
Author: J.D. Adachi
Author: S. Adami
Author: S. Boonen
Author: J. Compston
Author: C. Cooper ORCID iD
Author: P. Delmas
Author: A. Diez-Perez
Author: S. Gelhbach
Author: S.L. Greenspan
Author: A. LaCroix
Author: R. Lindsay
Author: J.C. Netenlenbos
Author: J. Pfeilschifter
Author: C. Roux
Author: K.C. Saag
Author: P. Sambrook
Author: S. Silverman
Author: E. Siris
Author: N.B. Watts
Author: F.A. Anderson Jr

Download statistics

Downloads from ePrints over the past year. Other digital versions may also be available to download e.g. from the publisher's website.

View more statistics

Atom RSS 1.0 RSS 2.0

Contact ePrints Soton: eprints@soton.ac.uk

ePrints Soton supports OAI 2.0 with a base URL of http://eprints.soton.ac.uk/cgi/oai2

This repository has been built using EPrints software, developed at the University of Southampton, but available to everyone to use.

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×