Browse by Divisions pre August 2011

Abutaily, A.S., Addis, B.J. and Roche, W.R. (2002) Immunohistochemistry in the distinction between malignant mesothelioma and pulmonary adenocarcinoma: a critical evaluation of new antibodies. Journal of Clinical Pathology, 55, (9), 662-668. (doi:10.1136/jcp.55.9.662).

Andrews, Allison-Lynn, Holloway, John W., Puddicombe, Sarah M., Holgate, Stephen T. and Davies, Donna E. (2002) Kinetic analysis of the interleukin-13 receptor complex. Journal of Biological Chemistry, 277, (48), 46073-46078. (doi:10.1074/jbc.M209560200).

Antunes, G., Evans, S.A., Lordan, J.L. and Frew, A.J. (2002) Systemic cytokine levels in community-acquired pneumonia and their association with disease severity. European Respiratory Journal, 20, (4), 990-995. (doi:10.1183/09031936.02.00295102).

Ardern-Jones, Michael R., Venning, Vanessa A. and Wojnarowska, Fenella (2002) Oral and topical corticosteroids in bullous pemphigoid. New England Journal of Medicine, 347, (2), 143-145.

Armstrong, T., Blaquiere, R.M., Varshney, S. and Primrose, J.N. (2002) Traumatic 'degloving' of the colon in blunt abdominal injury. Colorectal Disease, 4, (2), 141-143. (doi:10.1046/j.1463-1318.2002.00321.x).

Armstrong, T., Walters, E., Varshney, S. and Johnson, C.D. (2002) Deficiencies of micronutrients, altered bowel function, and quality of life during late follow-up after pancreaticoduodenectomy for malignancy. Pancreatology, 2, (6), 528-534. (doi:10.1159/000066095).

Babu, K.S. and Holgate, S.T. (2002) Newer therapies for asthma: a focus on anti-IgE. The Indian Journal of Chest Diseases & Allied Sciences, 44, (2), 107-115.

Babu, K.S. and Holgate, S.T. (2002) The role of anti-IgE therapies in the treatment of asthma. Hospital Medicine, 63, (8), 483-486.

Bakakos, P., Pickard, C., Smith, J.L. and Frew, A.J. (2002) TCR usage and cytokine expression in peripheral blood and BAL T cells. Clinical and Experimental Immunology, 128, (2), 295-301. (doi:10.1046/j.1365-2249.2002.01847.x).

Baldwin, Lindsay and Roche, William R. (2002) Does remodelling of the airway wall precede asthma? Paediatric Respiratory Reviews, 3, (4), 315-320. (doi:10.1016/S1526054202002610).

Bateman, A.C., Turner, S.M., Thomas, K.S., McCrudden, P.R., Fine, D.R., Johnson, P.A., Johnson, C.D. and Iredale, J.P. (2002) Apoptosis and proliferation of acinar and islet cells in chronic pancreatitis: evidence for differential cell loss mediating preservation of islet function. Gut, 50, (4), 542-548. (doi:10.1136/gut.50.4.542).

Beil, Waltraud J., McEuen, Alan R., Schulz, Matthias, Wefelmeyer, Udo, Kraml, Georg, Walls, Andrew F., Jensen-Jarolim, Erika, Pabst, Reinhard and Pammer, Johannes (2002) Selective alterations in mast cell subsets and eosinophil infiltration in two complementary types of intestinal inflammation: ascariasis and Crohn's disease. Pathobiology, 70, (6), 303-313. (doi:10.1159/000071270).

Belgi, G. and Friedmann, P.S. (2002) Traditional therapies: glucocorticoids, azathioprine, methotrexate, hydroxyurea. Clinical and Experimental Dermatology, 27, (7), 546-554. (doi:10.1046/j.1365-2230.2002.01146.x).

Botella, Luisa M., Sánchez-Elsner, Tilman, Sanz-Rodriguez, Francisco, Kojima, Soichi, Shimada, Jun, Guerrero-Esteo, Mercedes, Cooreman, Michael P., Ratziu, Vlad, Langa, Carmen, Vary, Calvin P.H., Ramírez, Jose R., Friedman, Scott and Bernabéu, Carmelo (2002) Transcriptional activation of endoglin and transforming growth factor-β signaling components by cooperative interaction between Sp1 and KLF6: their potential role in the response to vascular injury. Blood, 100, (12), 4001-4010. (doi:10.1182/blood.V100.12.4001).

Bowen, H., Biggs, T.E., Phillips, E., Baker, S.T., Perry, V.H., Mann, D.A. and Barton, C.H. (2002) c-Myc represses and Miz-1 activates the murine natural resistance-associated protein 1 promoter. Journal of Biological Chemistry, 277, (38), 34997-35006. (doi:10.1074/jbc.M204232200).

Brightling, Christopher E., Bradding, Peter, Symon, Fiona A., Holgate, Stephen T., Wardlaw, Andrew J. and Pavord, Ian D. (2002) Mast-cell infiltration of airway smooth muscle in asthma. New England Journal of Medicine, 346, (22), 1699-1705.

Brooks, Corinne L. and Rosenberg, William M. (2002) Assessment and management of chronic hepatitis C infection. Clinical Medicine, 2, (4), 302-306.

Brooks, S., Clark, G.T., Wright, S.M., Trueman, R.J., Postle, A.D., Cossins, A.R. and Maclean, N.M. (2002) Electrospray ionisation mass spectrometric analysis of lipid restructuring in the carp (Cyprinus carpio L.) during cold acclimation. Journal of Experimental Biology, 205, (24), 3989-3997.

Brunekreef, B. and Holgate, S.T. (2002) Air pollution and health. Lancet, 360, (9341), 1233-1242. (doi:10.1016/S0140-6736(02)11274-8).

Bucchieri, Fabio, Puddicombe, Sarah M., Lordan, James L., Richter, Audrey, Buchanan, Diane, Wilson, Susan J., Ward, Jon, Zummo, Giovanni, Howarth, Peter H., Djukanovic, Ratko, Holgate, Stephen T. and Davies, Donna E. (2002) Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis. American Journal of Respiratory Cell and Molecular Biology, 27, (2), 179-185.

Buckley, M.G., McEuen, A.R. and Walls, A.F. (2002) The return of the basophil. Clinical and Experimental Allergy, 32, (1), 8-10. (doi:10.1046/j.0022-0477.2001.01332.x).

Butterworth, J.R., Rosenberg, W.M.C., Jobson, S., Briggs, D., Howell, W. M., Iqbal, T.H. and Cooper, B.T. (2002) South Asian coeliacs resident in Britain possess distinct HLA haplotypes compared with White Caucasian patients. Gut, 50, (Supplement 2), A90-A90. (doi:10.1136/gut.50.suppl_2.a89).

Butterworth, Jeffrey R., Cooper, Brian T., Rosenberg, William M., Purkiss, Michael, Jobson, Shirley, Hathaway, Mark, Briggs, David, Howell, W. Martin, Wood, Gordon M., Adams, David H. and Iqbal, Tariq H. (2002) The role of hemochromatosis susceptibility gene mutations in protecting against iron deficiency in celiac disease. Gastroenterology, 123, (2), 444-449. (doi:10.1053/gast.2002.34778).

Chen, Zhilin, Lambden, Paul R., Lau, Jeshen, Caul, E. Owen and Clarke, Ian N. (2002) Human group C rotavirus: completion of the genome sequence and gene coding assignments of a non-cultivatable rotavirus. Virus Research, 83, (1-2), 179-187. (doi:10.1016/S0168-1702(01)00442-7).

Cho, S.H., Stanciu, L.A., Begishivili, T., Bates, P.J., Holgate, S.T. and Johnston, S.L. (2002) Peripheral blood CD4+ and CD8+ T cell type 1 and type 2 cytokine production in atopic asthmatic and normal subjects. Clinical and Experimental Allergy, 32, (3), 427-433. (doi:10.1046/j.1365-2222.2002.01281.x).

Christodoulides, Myron, Makepeace, Benjamin L., Partridge, Kris A., Kaur, Davindaur, Fowler, Mark I., Weller, Roy O. and Heckels, John E. (2002) Interaction of Neisseria meningitidis with human meningeal cells induces the secretion of a distinct group of chemotactic, proinflammatory, and growth-factor cytokines. Infection and Immunity, 70, (8), 4035-4044. (doi:10.1128/IAI.70.8.4035-4044.2002).

Church, M.K., Griffiths, T.J., Jeffery, S., Ravell, L.C., Cowburn, A.S., Sampson, A.P. and Clough, G.F. (2002) Are cysteinyl leukotrienes involved in allergic responses in human skin. Clinical and Experimental Allergy, 32, (7), 1013-1019. (doi:10.1046/j.1365-2222.2002.01436.x).

Church, Martin K. and McGill, James I. (2002) Human ocular mast cells. Current Opinion in Allergy and Clinical Immunology, 2, (5), 419-422.

Clark, Howard, Palaniyar, Nades, Strong, Peter, Edmondson, Jess, Hawgood, Samuel and Reid, Kenneth B.M. (2002) Surfactant protein D reduces alveolar macrophage apoptosis In vivo. Journal of Immunology, 169, (6), 2892-2899.

Clough, G.F., Boutsiouki, P., Church, M.K. and Michel, C.C. (2002) Effects of blood flow on the in vivo recovery of a small diffusible molecule by microdialysis in human skin. The Journal of Pharmacology and Experimental Therapeutics, 302, (2), 681-686.

Clough, Geraldine F. and Church, Martin K. (2002) Vascular responses in the skin: an accessible model of inflammation. News in Physiological Sciences, 17, (4), 170-174. (doi:10.1152/nips.01378.2001).

Collins, J.E. (2002) Adhesion between dendritic cells and epithelial cells maintains the gut barrier during bacterial sampling. Gut, 50, (4), 449-450. (doi:10.1136/gut.50.4.449).

Corne, Jonathan M., Marshall, Clare, Smith, Sandra, Schreiber, Jacquie, Sanderson, Gwendolyn, Holgate, Stephen T. and Johnston, Sebastian L. (2002) Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study. The Lancet, 359, (9309), 831-834. (doi:10.1016/S0140-6736(02)07953-9).

Coward, William R., Okayama, Yoshimichi, Sagara, Hironori, Wilson, Susan J., Holgate, Stephen T. and Church, Martin K. (2002) NF-κB and TNF-α: a positive autocrine loop in human lung mast cells? Journal of Immunology, 169, (9), 5287-5293.

Dahlén, Sven-Erik, Malmstrom, Kerstin, Nizankowska, Ewa, Dahlén, Barbro, Kuna, Piotr, Kowalski, Marek, Lumry, William R., Picado, César, Stevenson, Donald D., Bousquet, Jean, Pauwels, Romain, Holgate, Stephen T., Shahane, Aditi, Zhang, Ji, Reiss, Theodore F. and Szczeklik, Andrew (2002) Improvement of aspirin-intolerant asthma by montelukast, a leukotriene antagonist. A randomized, double-blind, placebo-controlled trial. American Journal of Respiratory and Critical Care Medicine, 165, (1), 9-14.

Davies, D.E. and Holgate, S.T. (2002) Asthma: the importance of epithelial mesenchymal communication in pathogenesis. Inflammation and the airway epithelium in asthma. The International Journal of Biochemistry & Cell Biology, 34, (12), 1520-1526. (doi:10.1016/S1357-2725(02)00048-1).

Davis, Andrew J., Pandher, Gurpreet K., Masson, Gordon M. and Sheron, Nick (2002) A severe case of ovarian hyperstimulation syndrome with liver dysfunction and malnutrition. European Journal of Gastroenterology and Hepatology, 14, (7), 779-782.

Dent, Gordon, Hosking, Lisa A., Lordan, James L., Steel, Mark D., Cruikshank, William W., Center, David M., Ellis, Jonathan H., Holgate, Stephen T., Davies, Donna E. and Djukanovic, Ratko (2002) Differential roles of IL-16 and CD28/B7 costimulation in the generation of T-lymphocyte chemotactic activity in the bronchial mucosa of mild and moderate asthmatic individuals. Journal of Allergy and Clinical Immunology, 110, (6), 906-914. (doi:10.1067/mai.2002.130049).

Djukanovic, Ratko (2002) Airway inflammation in asthma and its consequences: implications for treatment in children and adults. Journal of Allergy and Clinical Immunology, 109, (6 Part 2), S539-S548. (doi:10.1067/mai.2002.124568).

Dorne, J.L.C.M., Walton, K., Slob, W. and Renwick, A.G. (2002) Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate? Food and Chemical Toxicology, 40, (11), 1633-1656. (doi:10.1016/S0278-6915(02)00117-5).

Edwards, A., Stevens, M., Holgate, S., Iikura, Y., Åberg, N., König, P., Reinhardt, D., Stenius-Aarniala, B., Warner, J., Weinberg, E., Callaghan, B. and Howell, J. (2002) Letter to the editor: Inhaled sodium cromoglycate in children with asthma. Thorax, 57, (3), 282-282.

Everson, J.S., Garner, S.A., Fane, B., Liu, B.L., Lambden, P.R. and Clarke, I.N. (2002) Biological properties and cell tropism of Chp2, a bacteriophage of the obligate intracellular bacterium Chlamydophila abortus. Journal of Bacteriology, 184, (10), 2748-2754. (doi:10.1128/JB.184.10.2748-2754.2002).

Fletcher, C.L., Ardern-Jones, M.R. and Hay, R. (2002) Widespread bullous eruption due to multiple bed bug bites. Clinical and Experimental Dermatology, 27, (1), 74-75. (doi:10.1046/j.0307-6938.2001.00967.x). (PMID:11952681).

Frew, A.J., Langley, S.J., Perrin, V. and Hertog, M.G.L. (2002) Effects of 4-week treatment with low-dose budesonide (100 μg BID) from a novel inhaler Airmax™ and from a conventional inhaler on bronchial hyper-responsiveness, lung function and symptoms in patients with mild asthma. Respiratory Medicine, 96, (7), 542-547. (doi:10.1053/rmed.2002.1290).

Friedmann, Peter S. (2002) The pathogenesis of atopic eczema. Hospital Medicine, 63, (11), 653-656.

Gaca, Marianna D. A., Zhou, Xiaoying and Benyon, R. Christopher (2002) Regulation of hepatic stellate cell proliferation and collagen synthesis by proteinase-activated receptors. Journal of Hepatology, 36, (3), 362-369. (doi:10.1016/S0168-8278(01)00285-9).

Gadola, Stephan D., Dulphy, Nicolas, Salio, Mariolina and Cerundolo, Vincenzo (2002) Valpha24-JalphaQ-independent, CD1d-restricted recognition of alpha-galactosylceramide by human CD4(+) and CD8alphabeta(+) T lymphocytes. Journal of Immunology, 168, 5514-5520. (PMID:12023346).

Gadola, Stephan D., Zaccai, Nathan R., Harlos, Karl, Shepherd, Dawn, Castro-Palomino, Julio C., Ritter, Gerd, Schmidt, Richard R., Jones, E. Yvonne and Cerundolo, Vincenzo (2002) Structure of human CD1b with bound ligands at 2.3 A, a maze for alkyl chains. Nature Immunology, 3, 721-726. (doi:10.1038/ni821).

Gadola, Stephan D., Zaccai, Nathan R., Harlos, Karl, Shepherd, Dawn, Castro-Palomino, Julio C., Ritter, Gerd, Schmidt, Richard R., Jones, E. Yvonne and Cerundolo, Vincenzo (2002) Structure of human CD1b with bound ligands at 2.3 Å, a maze for alkyl chains. Nature Immunology, 3, (8), 721-726. (doi:10.1038/ni821).

Gao, Runping, McCormick, Christopher J., Arthur, Michael J., Ruddell, Richard, Oakley, Fiona, Smart, David E., Murphy, Frank R., Harris, Mark P. and Mann, Derek A. (2002) High efficiency gene transfer into cultured primary rat and human hepatic stellate cells using baculovirus vectors. Liver International, 22, (1), 15-22. (doi:10.1046/j.0106-9543.2001.01555.x).

Gonzales, Linda W., Guttentag, Susan H., Wade, Kelly C., Postle, Anthony D. and Ballard, Philip L. (2002) Differentiation of human pulmonary type II cells in vitro by glucocorticoid plus cAMP. American Journal of Physiology. Lung Cellular and Molecular Physiology, 283, (5), L940-L951.

Grundy, Jane, Matthews, Sharon, Bateman, Belinda, Dean, Taraneh and Arshad, Syed Hasan (2002) Rising prevalence of allergy to peanut in children: Data from 2 sequential cohorts. Journal of Allergy and Clinical Immunology, 110, (5), 784-789. (doi:10.1067/mai.2002.128802).

Hamblin, Terry J., Orchard, Jenny A., Ibbotson, Rachel E., Davis, Zadie, Thomas, Peter W., Stevenson, Freda K. and Oscier, David G. (2002) CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease. Blood, 99, (3), 1023-1029. (doi:10.1182/blood.V99.3.1023).

Hansel, T.T., Sterk, P.J., Holgate, S.T. and Barnes, P.J. (2002) The trials and tribulations of anti-IL-5 em leader. Journal of Allergy and Clinical Immunology, 109, (3), 575-576.

Harrison, O.B., Robertson, B.D., Faust, S.N., Jepson, M.A., Goldin, R.D., Levin, M. and Heyderman, R.S. (2002) Analysis of pathogen-host cell interactions in purpura fulminans: expression of capsule, type IV pili, and PorA by Neisseria meningitidis in vivo. Infection and Immunity, 70, (9), 5193-5201. (doi:10.1128/IAI.70.9.5193-5201.2002).

Hochhaus, A., Berger, U., Reiter, A., Engelich, G., Lahaye, T., Kreil, S., Merx, K., Muller, M.C. and Hehlmann, R. (2002) [Current therapy concepts in chronic myeloid leukemia. Study IV of the German CML Study Group]. Internist (Berl), 43, (10), 1231-1238.

Hoffman, Elizabeth G., Day, Ian N. M. and Ganderton, Rosalind H. (2002) Age-associated changes in methylation of the insulin-like growth factor II (IGF-II) gene. Mechanisms of Ageing and Development, 123, (4), 442-443. (doi:10.1016/S0047-6374(01)00381-5).

Holgate, S.T. (2002) Considerations on third generation antihistamines. Clinical and Experimental Allergy, 32, (2), p.179. (doi:10.1046/j.1365-2222.2002.01339.x).

Holgate, S.T. and Salvi, S.S. (2002) Mast cell tryptase as a proinflamatory mediator in late-phase asthmatic response. Current Allergy and Asthma Reports, 2, (2), 105-106.

Holgate, Stephen T. (2002) Adenosine provocation: a new test for allergic type airway inflammation. American Journal of Respiratory and Critical Care Medicine, 165, (3), 317-318.

Holgate, Stephen T. (2002) Adenosine: a key effector molecule of asthma or just another mediator. American Journal of Physiology. Lung Cellular and Molecular Physiology, 282, (2), L167-L168. (doi:10.1152/ajplung.00386.2001).

Holgate, Stephen T. (2002) Airway inflammation and remodeling in asthma: current concepts. Molecular Biotechnology, 22, (2), 179-189.

Holgate, Stephen T. (2002) Asthma: more than an inflammatory disease. Current Opinion in Allergy and Clinical Immunology, 2, (1), 27-29.

Hourihane, Jonathan O'B. (2002) Recent advances in peanut allergy. Current Opinion in Allergy and Clinical Immunology, 2, (3), 227-231.

Howarth, P. (2002) Antihistamines in rhinoconjunctivitis. Clinical Allergy and Immunology, 17, 179-220.

Howat, William J., Barabas, Tony, Holmes, James A., Holgate, Stephen T. and Lackie, Peter M. (2002) Distribution of basement membrane pores in bronchus revealed by microscopy following epithelial removal. Journal of Structural Biology, 139, (3), 137-145. (doi:10.1016/S1047-8477(02)00589-0).

Howat, William J., Holgate, Stephen T. and Lackie, Peter M. (2002) TGF-β isoform release and activation during in vitro bronchial epithelial wound repair. American Journal of Physiology: Lung Cellular and Molecular Physiology, 282, (1), L115-L123.

Howell, W.M., Turner, S.J., Collins, A., Bateman, A.C. and Theaker, J.M. (2002) Influence of TNFalpha and LTalpha single nucleotide polymorphisms on susceptibility to and prognosis in cutaneous malignant melanoma in the British population. European Journal of Immunogenetics, 29, (1), 17-23. (doi:10.1046/j.1365-2370.2002.00269.x).

Humphries, Holly E., Christodoulides, Myron and Heckels, John E. (2002) Expression of the Class 1 outer-membrane protein of Neisseria meningitidis in Escherichia coli and purification using a self-cleavable affinity tag. Protein Expression and Purification, 26, (2), 243-248. (doi:10.1016/S1046-5928(02)00534-X).

Hunt, Alan N., Clark, Graeme T., Neale, James R. and Postle, Anthony D. (2002) A comparison of the molecular specificities of whole cell and endonuclear phosphatidylcholine synthesis. FEBS letters, 530, (1-3), 89-93. (doi:10.1016/S0014-5793(02)03429-4).

Jones, C.A., Holloway, J.A., Popplewell, E.J., Diaper, N.D., Holloway, J.W., Vance, G.H.S., Warner, J.A. and Warner, J.O. (2002) Reduced soluble CD14 levels in amniotic fluid and breast milk are associated with the subsequent development of atopy, eczema, or both. Journal of Allergy and Clinical Immunology, 109, (5), 858-866. (doi:10.1067/mai.2002.123535).

Jones, C.A., Holloway, J.A. and Warner, J.O. (2002) Phenotype of fetal monocytes and B lymphocytes during the third trimester of pregnancy. Journal of Reproductive Immunology, 56, (1-2), 45-60. (doi:10.1016/S0165-0378(02)00022-0).

Jones, Catherine A., Holloway, Judith A. and Warner, John O. (2002) Fetal immune responsiveness and routes of allergic sensitization. Pediatric Allergy and Immunology, 13, 19-22. (doi:10.1034/j.1399-3038.13.s.15.6.x).

Jordens, J. Zoe, Williams, Jeannette N., Jones, Graeme R. and Heckels, John E. (2002) Detection of meningococcal carriage by culture and PCR of throat swabs and mouth gargles. Journal of Clinical Microbiology, 40, 75-79. (doi:10.1128/JCM.40.1.75-79.2002).

Khakoo, Salim I., Geller, Ron, Shin, Sunny, Jenkins, Jomaquai A. and Parham, Peter (2002) The D0 domain of KIR3D acts as a major histocompatibility complex class I binding enhancer. The Journal of Experimental Medicine, 196, (7), 911-921. (doi:10.1084/jem.20020304).

Khan, S.A., Davidson, B.R., Goldin, R., Pereira, S.P., Rosenberg, W.M., Taylor-Robinson, S.D., Thillainayagam, A.V., Thomas, H.C., Thursz, M.R. and Wasan, H. (2002) Guidelines for the diagnosis and treatment of cholangiocarcinoma: consensus document. Gut, 51, (6), vi1-vi9. (doi:10.1136/gut.51.suppl_6.vi1).

Krishna, M.T., Hatzivlassiou, P., Salvi, S.S. and Holgate, S.T. (2002) Current and future asthma therapies. Practitioner, 246, (1641), 820-825.

Lancaster, T., Sanders, E., Christie, J.M.L., Brooks, C., Green, S. and Rosenberg, W.M.C. (2002) Quantitative and functional differences in CD8+ lymphocyte responses in resolved acute and chronic hepatitis C virus infection. Journal of Viral Hepatitis, 9, (1), 18-28. (doi:10.1046/j.1365-2893.2002.00330.x).

Legg, J.P., Jones, C.A., Warner, J.A., Johnston, S.L. and Warner, J.O. (2002) A hypothesis: antenatal sensitisation to respiratory syncytial virus in viral bronchiolitis. Archives of Disease in Childhood, 86, (6), 431-433. (doi:10.1136/adc.86.6.431).

Lewith, G.T., Watkins, A.D., Hyland, M.E., Shaw, S., Broomfield, J.A., Dolan, G. and Holgate, S.T. (2002) Use of ultramolecular potencies of allergen to treat asthmatic people allergic to house dust mite: double blind randomised controlled clinical trial. British Medical Journal, 324, (7336), 520-[5pp]. (doi:10.1136/bmj.324.7336.520).

Lordan, J.L. and Holgate, S.T. (2002) H1-antihistamines in asthma. Clinical Sllergy and Immunology, 17, 221-248.

Lordan, James L., Bucchieri, Fabio, Richter, Audrey, Konstantinidis, Athanassias, Holloway, John W., Thornber, Matthew, Puddicombe, Sarah M., Buchanan, Diana, Wilson, Susan J., Djukanović, Ratko, Holgate, Stephen T. and Davies, Donna E. (2002) Cooperative effects of Th2 cytokines and allergen on normal and asthmatic bronchial epithelial cells. Journal of Immunology, 169, (1), 407-414.

Louis, R.E., Cataldo, D., Buckley, M.G., Sele, J., Henket, M., Lau, L.C., Bartsch, P., Walls, A.F. and Djukanovic, R. (2002) Evidence of mast-cell activation in a subset of patients with eosinophilic chronic obstructive pulmonary disease. European Respiratory Journal, 20, (2), 325-331.

Löwhagen, O., Wever, A.M.J., Lusuardi, M., Moscato, G., De Backer, W.A., Gandola, L., Donner, C.F., Ahlstedt, S., Larsson, L. and Holgate, S.T. (2002) The inflammatory marker serum eosinophil cationic protein (ECP) compared with PEF as a tool to decide inhaled corticosteroid dose in asthmatic patients. Respiratory Medicine, 96, (2), 95-101. (doi:10.1053/rmed.2001.1218).

Mander, Ann, Langton-Hewer, Simon, Bernhard, Wolfgang, Warner, John O. and Postle, Anthony D. (2002) Altered phospholipid composition and aggregate structure of lung surfactant is associated with impaired lung function in young children with respiratory infections. American Journal of Respiratory Cell and Molecular Biology, 27, (6), 714-721. (doi:10.1165/rcmb.4746).

Mann, D.A. (2002) The NFkB luciferase mouse: a new tool for real time measurement of NFkB activation in the whole animal. Gut, 51, (6), 769-770.

Mann, D.A. and Smart, D.E. (2002) Transcriptional regulation of hepatic stellate cell activation. Gut, 50, (6), 891-896.

Mann, Jelena, Oakley, Fiona, Johnson, Peter W.M. and Mann, Derek A. (2002) CD40 induces interleukin-6 gene transcription in dendritic cells: regulation by TRAF2, AP-1, NF-κB, AND CBF1. The Journal of Biological Chemistry, 277, (19), 17125-17138. (doi:10.1074/jbc.M109250200).

Mason, Paul S., Adam, Elizabeth, Prior, Matthew, Warner, John O. and Randall, Christopher J. (2002) Effect of bacterial endotoxin and middle ear effusion on ciliary activity: implications for otitis media. Laryngoscope, 112, (4), 676-680.

McArdle, F., Rhodes, L.E., Parslew, R., Jack, C.I.A., Friedmann, P.S. and Jackson, M.J. (2002) UVR-induced oxidative stress in human skin in vivo: effects of oral vitamin C supplementation. Free Radical Biology & Medicine, 33, (10), 1355-1362. (doi:10.1016/S0891-5849(02)01042-0).

McCann, Donna, McWhirter, Jenny, Coleman, Helen, Devall, Isobel, Calvert, Marguerite, Weare, Katherine and Warner, John (2002) The prevalence and management of asthma in primary-aged schoolchildren in the south of England. Health Education Research, 17, (2), 181-194.

McCormick, Christopher J., Rowlands, David J. and Harris, Mark (2002) Efficient delivery and regulable expression of hepatitis C virus full-length and minigenome constructs in hepatocyte-derived cell lines using baculovirus vectors. The Journal of General Virology, 83, (2), 383-394.

Melcher, Alan, Bateman, Andrew, Harrington, Kevin, Ahmed, Atique, Gough, Michael and Vile, Richard (2002) Dendritic cells for the immunotherapy of cancer. Clinical Oncology, 14, (3), 185-192. (doi:10.1053/clon.2001.0038).

Millar, Timothy, Kanczler, Janos, Bodamyali, Tulin, Blake, David and Stevens, Cliff (2002) Xanthine oxidase is a peroxynitrite synthase: newlyidentified roles for a very old enzyme. Redox Report, 7, (2), 65-70. (doi:10.1179/135100002125000280). (PMID:12189051).

Murphy, Frank, Arthur, Michael and Iredale, John (2002) Developing strategies for liver fibrosis treatment. Expert Opinion on Investigational Drugs, 11, (11), 1575-1585. (doi:10.1517/13543784.11.11.1575).

Murphy, Frank R., Issa, Razao, Zhou, Xiaoying, Ratnarajah, Shabna, Nagase, Hideaki, Arthur, Michael J.P., Benyon, Christopher and Iredale, John P. (2002) Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis. The Journal of Biological Chemistry, 277, (13), 11069-11076. (doi:10.1074/jbc.M111490200).

Oscier, David G., Gardiner, Anne C., Mould, Sarah J., Glide, Sharron, Davis, Zadie A., Ibbotson, Rachel E., Corcoran, Martin M., Chapman, Robert M., Thomas, Peter W., Copplestone, J. Adrian, Orchard, Jenny A. and Hamblin, Terry J. (2002) Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors. Blood, 100, (4), 1177-1184.

Paananen, Reija, Postle, Anthony D., Clark, Graeme, Glumoff, Virpi and Hallman, Mikko (2002) Eustachian tube surfactant is different from alveolar surfactant: determination of phospholipid composition of porcine eustachian tube lavage fluid. Journal of Lipid Research, 43, (1), 99-106.

Papadopoulos, N.G., Stanciu, L.A., Papi, A., Holgate, S.T. and Johnston, S.L. (2002) A defective type 1 response to rhinovirus in atopic asthma. Thorax, 57, (4), 328-332.

Papadopoulos, N.G., Stanciu, L.A., Papi, A., Holgate, S.T. and Johnston, S.L. (2002) Rhinovirus-induced alterations on peripheral blood mononuclear cell phenotype and costimulatory molecule expression in normal and atopic asthmatic subjects. Clinical and Experimental Allergy, 32, (4), 537-542. (doi:10.1046/j.0954-7894.2002.01313.x).

Papi, Alberto, Papadopoulos, Nikolaos, Stanciu, Luminita A., Bellettato, Cinzia M., Pinamonti, Silvano, Degitz, Klaus, Holgate, Stephen T. and Johnston, Sebastian L. (2002) Reducing agents inhibit rhinovirus-induced up-regulation of the rhinovirus receptor intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells. FASEB Journal, 16, (14), 1934-1936. (doi:10.1096/fj.02-0118fje).

Parnia, S., Brown, J.L. and Frew, A.J. (2002) The role of pollutants in allergic sensitization and the development of asthma. Allergy, 57, (12), 1111-1117. (doi:10.1034/j.1398-9995.2002.02167.x).

Polosa, R., Rorke, S. and Holgate, S.T. (2002) Evolving concepts on the value of adenosine hyperresponsiveness in asthma and chronic obstructive pulmonary disease. Thorax, 57, (7), 649-654. (doi:10.1136/thorax.57.7.649).

Polosa, Riccardo, Puddicombe, Sarah M., Krishna, M. Thirumala, Tuck, Angela B., Howarth, Peter H., Holgate, Stephen T. and Davies, Donna E. (2002) Expression of c-erbB receptors and ligands in the bronchial epithelium of asthmatic subjects. Journal of Allergy and Clinical Immunology, 109, (1), 75-81. (doi:10.1067/mai.2002.120274).

Poullis, A., Moodie, S.J. and Maxwell, J.D. (2002) Clinical haemochromatosis in HFE mutation carriers. The Lancet, 360, (9330), 412-413. (doi:10.1016/S0140-6736(02)09581-8).

Power, Lynsey L., Popplewell, Eleanor J., Holloway, Judith A., Diaper, Norma D., Warner, John O. and Jones, Catherine A. (2002) Immunoregulatory molecules during pregnancy and at birth. Journal of Reproductive Immunology, 56, (1-2), 19-28. ( doi:10.1016/S0165-0378(01)00146-2).

Proikas-Cezanne, Tassula, Stabel, Silvia and Riethmacher, Dieter (2002) Identification of protein tyrosine phosphatase 1B and casein as substrates for 124-v-Mos. BMC Biochemistry, 3, (6), 1-7. (doi:10.1186/1471-2091-3-6).

Prosperini, Gaetano, Rajakulasingam, Kajakulasingam, Cacciola, Rossella R., Spicuzza, Lucia, Rorke, Steuart, Holgate, Stephen T., Di Maria, Giuseppe U. and Polosa, Riccardo (2002) Changes in sputum counts and airway hyperresponsiveness after budesonide: monitoring anti-inflammatory response on the basis of surrogate markers of airway inflammation. Journal of Allergy and Clinical Immunology, 110, (6), 855-861. (doi:10.1067/mai.2002.130050).

Reitamo, Sakari, Rustin, Malcolm, Ruzicka, Thomas, Cambazard, Frédéric, Kalimo, Kirsti, Friedmann, Peter S., Schoepf, Erwin, Lahfa, Mourad, Diepgen, Thomas L., Judodihardjo, Harryono, Wollenberg, Andreas, Berth-Jones, John and Bieber, Thomas (2002) Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone butyrate ointment in adult patients with atopic dermatitis. Journal of Allergy and Clinical Immunology, 109, (3), 547-555. (doi:10.1067/mai.2002.121832).

Renwick, Andrew G. (2002) Pesticide residue analysis and its relationship to hazard characterisation (ADI/ARfD) and intake estimations (NEDI/NESTI). Pest Management Science, 58, (10), 1073-1082. (doi:10.1002/ps.544).

Rhodes, Helen L., Thomas, Peter, Sporik, Richard, Holgate, Stephen T. and Cogswell, Jeremy J. (2002) A birth cohort study of subjects at risk of atopy: twenty-two-year follow-up of wheeze and atopic status. American Journal of Respiratory and Critical Care Medicine, 165, (2), 176-180. (doi:10.1164/rccm2104032).

Richter, Audrey, O'Donnell, Rory A., Powell, Robert M., Sanders, Michael W., Holgate, Stephen T., Djukanovic', Ratko and Davies, Donna E. (2002) Autocrine ligands for the epidermal growth factor receptor mediate interleukin-8 release from bronchial epithelial cells in response to cigarette smoke. American Journal of Respiratory Cell and Molecular Biology, 27, (1), 85-90.

Ritz, Stacey A., Stampfli, Martin R., Davies, Donna E., Holgate, Stephen T. and Jordana, Manel (2002) On the generation of allergic airway diseases: from GM-CSF to Kyoto. Trends in Immunology, 23, (8), 396-402. (doi:10.1016/S1471-4906(02)02278-0).

Roberts, G., Golder, N. and Lack, G. (2002) Bronchial challenges with aerosolized food in asthmatic, food-allergic children. Allergy, 57, (8), 713-717. (doi:10.1034/j.1398-9995.2002.03366.x).

Robinson, Samantha, Clarke, Ian N., Vipond, I. Barry, Caul, E. Owen and Lambden, Paul R. (2002) Epidemiology of human sapporo-like caliciviruses in the South West of England: molecular characterisation of a genetically distinct isolate. Journal of Medical Virology, 67, (2), 282-288. (doi:10.1002/jmv.2219).

Robinson, Samantha J. and Healy, Eugene (2002) Human melanocortin 1 receptor (MC1R) gene variants alter melanoma cell growth and adhesion to extracellular matrix. Oncogene, 21, (52), 8037-8046. (doi:10.1038/sj.onc.1205913).

Roche, W.R. (2002) Expert commentary. Histopathology, 41, (3A), 20-21. (doi:10.1046/j.1365-2559.2002.14712.x).

Rorke, S. and Holgate, S.T. (2002) Targeting adenosine receptors: novel therapeutic targets in asthma and chronic obstructive pulmonary disease. American Journal of Respiratory Medicine, 1, (2), 99-105.

Rorke, S., Jennison, S., Jeffs, J.A., Sampson, A.P., Arshad, H. and Holgate, S.T. (2002) Role of cysteinyl leukotrienes in adenosine 5'-monophosphate induced bronchoconstriction in asthma. Thorax, 57, (4), 323-327.

Rosenberg, William and Davis, Andrew (2002) Haemochromatosis. Medicine, 30, (12: Liver 2), 63-65. (doi:10.1383/medc.30.12.63.28523).

Rosenberg, William M.C. (2002) Success in treating mild chronic hepatitis C: different outcomes - new guidelines? European Journal of Gastroenterology and Hepatology, 14, (6), 595-597.

Salmela, M.T., MacDonald, T.T., Black, D., Irvine, B., Zhuma, T., Saarialho-Kere, U. and Pender, S.L.F. (2002) Upregulation of matrix metalloproteinases in a model of T cell mediated tissue injury in the gut: analysis by gene array and in situ hybridisation. Gut, 51, (4), 540-547.

Seymour, Michelle L., Gilby, Natalie, Bardin, Phillip G., Fraenkel, David J., Sanderson, Gwendolyn, Penrose, John F., Holgate, Stephen T., Johnston, Sebastian L and Sampson, Anthony P. (2002) Rhinovirus infection increases 5-lipoxygenase and cyclooxygenase-2 in bronchial biopsy specimens from nonatopic subjects. Journal of Infectious Diseases, 185, (4), 540-544. (doi:10.1086/338570).

Shek, Fanny Wai-Tsing, Benyon, Robert Christopher, Walker, Fiona Mairi, McCrudden, Peter Raymond, Pender, Sylvia Lin Foon, Williams, Elizabeth Jean, Johnson, Penelope Ann, Johnson, Colin David, Bateman, Adrian Calvin, Fine, David Roger and Iredale, John Peter (2002) Expression of transforming growth factor-ß1 by pancreatic stellate cells and its implications for matrix secretion and turnover in chronic pancreatitis. American Journal of Pathology, 160, (5), 1787-1798.

Stein, K., Rosenberg, W. and Wong, J. (2002) Cost effectiveness of combination therapy for hepatitis C: a decision analytic model. Gut, 50, (2), 253-258. (doi:10.1136/gut.50.2.253).

Stephanou, Anastasis, Scarabelli, Tiziano M., Townsend, Paul A., Bell, Robert, Yellon, Derek, Knight, Richard A. and Latchman, David S. (2002) The carboxyl-terminal activation domain of the STAT-1 transcription factor enhances ischemia/reperfusion-induced apoptosis in cardiac myocytes. Federation of American Societies for Experimental Biology (FASEB) Journal, 16, (13), 1841-1843. (doi:10.1096/fj.02-0150fje).

Sánchez-Elsner, Tilman, Botella, Luisa M., Velasco, Beatriz, Langa, Carmen and Bernabéu, Carmelo (2002) Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways. Journal of Biological Chemistry, 277, (46), 43799-43808. (doi:10.1074/jbc.M207160200).

Tang, Augustine T.M., Velissaris, Theodore J., Tsang, Geoffrey and Roche, William (2002) Bronchial artery dissection and fatal hemothorax following pneumonectomy. Asian Cardiovascular and Thoracic Annals, 10, (2), 191-193.

Thirdborough, Stephen M., Radcliffe, Joanna N., Friedmann, Peter S. and Stevenson, Freda K. (2002) Vaccination with DNA encoding a single-chain TCR fusion protein induces anticlonotypic immunity and protects against T-cell lymphoma. Cancer Research, 62, (6), 1757-1760.

Thornton, Catherine A., Holloway, Judith A. and Warner, John O. (2002) Expression of CD21 and CD23 during human fetal development. Pediatric Research, 52, (2), 245-250. (doi:10.1203/01.PDR.0000023172.89966.50).

Torr, T., Gaughan, M., Roberts, G., Bynoe, Y., Semple, E., Lack, G. and Butler, J. (2002) Food challenges: a review and audit. Paediatric Nursing, 14, (9), 30-34.

Van Eerdewegh, Paul, Little, Randall D., Dupuis, Josée, Del Mastro, Richard G., Falls, Kathy, Simon, Jason, Torrey, Dana, Pandit, Sunil, McKenny, Joyce, Braunschweiger, Karen, Walsh, Alison, Liu, Ziying, Hayward, Brooke, Folz, Colleen, Manning, Susan P., Bawa, Alicia, Saracino, Lisa, Thackston, Michelle, Benchekroun, Youssef, Capparell, Neva, Wang, Mei, Adair, Ron, Feng, Yun, Dubois, JoAnn, FitzGerald, Michael G., Huang, Hui, Gibson, René, Allen, Kristina M., Pedan, Alex, Danzig, Melvyn R., Umland, Shelby P., Egan, Robert W., Cuss, Francis M., Rorke, Steuart, Clough, Joanne B., Holloway, John W., Holgate, Stephen T. and Keith, Tim P. (2002) Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature, 418, (6896), 426-430. (doi:10.1038/nature00878).

Vance, Gillian H.S. and Holloway, Judith A. (2002) Early life exposure to dietary and inhalant allergens. Pediatric Allergy and Immunology, 13, (s15), 14-18. (doi:10.1034/j.1399-3038.13.s.15.5.x).

Verrill, Clare, Davies, Janice, Millward-Sadler, Harry, Sundstrom, Lars and Sheron, Nick (2002) Organotypic liver culture in a fluid-air interface using slices of neonatal rat and adult human tissue - a model of fibrosis in vitro. Journal of Pharmacological and Toxicological Methods, 48, (2), 103-110. (doi:10.1016/S1056-8719(03)00042-X).

Wallin, A.T., Cioppa, G.D., Holgate, S. and Wilson, S. (2002) The effects of regular inhaled formoterol and budesonide on preformed Th-2 cytokines in mild asthmatics. Respiratory Medicine, 96, (12), 1021-1025. (doi:10.1053/rmed.2002.1388).

Watson, L., Margetts, B., Howarth, P., Dorward, M., Thompson, R. and Little, P. (2002) The association between diet and chronic obstructive pulmonary disease in subjects selected from general practice. European Respiratory Journal, 20, (2), 313-318.

Welch, S. and Faust, S.N. (2002) Prescribing in children. Diagnosis and treatment of serious infections. Prescriber, 13, (4), 76-84.

Winter, Craig D., Iannotti, Fausto, Pringle, Ashley K., Trikkas, Christos, Clough, Geraldine F. and Church, Martin K. (2002) A microdialysis method for the recovery of IL-1beta, IL-6 and nerve growth factor from human brain in vivo. Journal of Neuroscience Methods, 119, (1), 45-50. (doi:10.1016/S0165-0270(02)00153-X).

Wright, J. Claire, Williams, Jeanette N., Christodoulides, Myron and Heckels, John E. (2002) Immunization with the recombinant PorB outer membrane protein induces a bactericidal immune response against Neisseria meningitidis. Infection and Immunity, 70, (8), 4028-4034. (doi:10.1128/IAI.70.8.4028-4034.2002).

Xu, J., Benyon, R.C., Leir, S.H., Zhang, S., Holgate, S.T. and Lackie, P.M. (2002) Matrix metalloproteinase-2 from bronchial epithelial cells induces the proliferation of subepithelial fibroblasts. Clinical and Experimental Allergy, 32, (6), 881-888. (doi:10.1046/j.1365-2745.2002.01386.x).

Yoshimura, Chitose, Yamaguchi, Masao, Iikura, Motoyasu, Izumi, Shinyu, Kudo, Koichiro, Nagase, Hiroyuki, Ishii, Akira, Walls, Andrew F., Ra, Chisei, Iwata, Tsutomu, Igarashi, Takashi, Yamamoto, Kazuhiko and Hirai, Koichi (2002) Activation markers of human basophils: CD69 expression is strongly and preferentially induced by IL-3. Journal of Allergy and Clinical Immunology, 109, (5), 817-823. (doi:10.1067/mai.2002.123532).

Yuyama, Noriko, Davies, Donna E., Akaiwa, Mina, Matsui, Keiko, Hamasaki, Yuhei, Suminami, Yoshinori, Yoshida, Ning Lu, Maeda, Miyako, Pandit, Anita, Lordan, James L., Kamogawa, Yumiko, Arima, Kazuhiko, Nagumo, Fumio, Sugimachi, Mitsuhiko, Berger, Ann, Richards, Ivan, Roberds, Steven L., Yamashita, Tetsuji, Kishi, Fumio, Kato, Hiroshi, Arai, Ken-Ichi, Ohshima, Koichi, Tadano, Jutaro, Hamasaki, Ken-Ichi, Miyatake, Shoichiro, Sugita, Yuji, Holgate, Stephen T. and Izuhara, Kenji (2002) Analysis of novel disease-related genes in bronchial asthma. Cytokine, 19, (6), 287-296. (doi:10.1006/cyto.2002.1972).

Zhang, J., Yu, C., Holgate, S.T. and Reiss, T.F. (2002) Variability and lack of predictive ability of asthma end-points in clinical trials. European Respiratory Journal, 20, (5), 1102-1109.