Browse by Divisions pre August 2011

The Academy of Medical Sciences (2004) Calling time. The nation's drinking as a major health issue. A report from the Academy of Medical Sciences. London, UK, Academy of Medical Sciences, 45pp.

Al-Bader, Tamara, Jolley, Keith A., Humphries, Holly E., Holloway, Judith, Heckels, John E., Semper, Amanda E., Friedmann, Peter S. and Christodoulides, Myron (2004) Activation of human dendritic cells by the PorA protein of Neisseria meningitidis. Cellular Microbiology, 6, (7), 651-662. (doi:10.1111/j.1462-5822.2004.00392.x).

Ali, Shakir and Mann, Derek A. (2004) Signal transduction via the NF-κB pathway: a targeted treatment modality for infection, inflammation and repair. Cell Biochemistry and Function, 22, (2), 67-79. (doi:10.1002/cbf.1082).

Armstrong, Thomas, Packham, Graham, Murphy, Lindsay B., Bateman, Adrian C., Conti, John A., Fine, David R., Johnson, Colin D., Benyon, R.Christopher and Iredale, John P. (2004) Type I collagen promotes the malignant phenotype of pancreatic ductal adenocarcinoma. Clinical Cancer Research, 10, (21), 7427-7437. (doi:10.1158/1078-0432.CCR-03-0825).

Asher, I., Baena-Cagnani, C., Boner, A., Canonica, G.W., Chuchalin, A., Custovic, A., Dagli, E., Haahtela, T., Haus, M., Lemmo-Hoten, M., Holgate, S., Holloway, J., Holt, P., Host, A., Iikura, Y., Johansson, S.G., Kaplan, A., Kowalski, M.L., Lockey, R.F., Naspitz, C., Odhiambo, J., Ring, J., Sastre, J., Venables, K., Vichyanond, P., Volovitz, B., Wahn, U., Warner, J., Weiss, K. and Zhong, N.S. (2004) World Allergy Organization guidelines for prevention of allergy and allergic asthma. International Archives of Allergy and Immunology, 135, (1), 83-92. (doi:10.1159/000080524).

Babu, K. Suresh, Davies, Donna E. and Holgate, Stephen T. (2004) Role of tumor necrosis factor alpha in asthma. Immunology and Allergy Clinics of North America, 24, (4), 583-597. (doi:10.1016/j.iac.2004.06.010).

Bateman, Adrian C. and Howell, W. Martin (2004) Genetic polymorphism, the immune response and chronic pancreatitis. In, Johnson, C.D. (ed.) Pancreatic Disease: Basic Science and Clinical Management. London, UK, Springer, 306-318.

Bateman, B., Warner, J.O., Hutchinson, E., Dean, T., Rowlandson, P., Gant, C., Grundy, J., Fitzgerald, C. and Stevenson, J. (2004) The effects of a double blind, placebo controlled, artificial food colourings and benzoate preservative challenge on hyperactivity in a general population sample of preschool children. Archives of Disease in Childhood, 89, (6), 506-511. (doi:10.1136/adc.2003.031435).

Batuwangala, Thil, Shepherd, Dawn, Gadola, Stephan D., Gibson, Kevin J., Zaccai, Nathan R., Fersht, Alan R., Besra, Gurdyal, Cerundolo, Vincenzo and Jones, E. Yvonne (2004) The crystal structure of human CD1b with a bound bacterial glycolipid. Journal of Immunology, 172, (4), 2382-2388. (PMID:14764708).

Beghé, B., Padoan, M., Moss, C.T., Barton, S.J., Holloway, J.W., Holgate, S.T., Howell, W.M. and Mapp, C.E. (2004) Lack of association of HLA class I genes and TNF α-308 polymorphism in toluene diisocyanate-induced asthma. Allergy, 59, (1), 61-64. (doi:10.1046/j.1398-9995.2003.00352.x).

Bernhard, Wolfgang, Pynn, Christopher J., Jaworski, Andreas, Rau, Gunnar A., Hohlfeld, Jens M., Freihorst, Joachim, Poets, Christian F., Stoll, Dieter and Postle, Anthony D. (2004) Mass spectrometric analysis of surfactant metabolism in human volunteers using deuteriated choline. American Journal of Respiratory and Critical Care Medicine, 170, (1), 54-58. (doi:10.1164/rccm.200401-089OC).

Bertrand-Philippe, Marie, Ruddell, Richard G., Arthur, Michael J.P., Thomas, James, Mungalsingh, Narenda and Mann, Derek A. (2004) Regulation of tissue inhibitor of metalloproteinase 1 gene transcription by RUNX1 and RUNX2. The Journal of Biological Chemistry, 279, (23), 24530-24539. (doi:10.1074/jbc.M311804200).

Bousquet, J. and Warner, J.O. (2004) Allergy and Pediatric Allergy and Immunology are the official organs of the European Academy of Allergology and Clinical Immunology. Allergy, 59, (12), 1333-1338. (doi:10.1111/j.1398-9995.2004.00766.x).

Bousquet, Jean, Wenzel, Sally, Holgate, Stephen, Lumry, William, Freeman, Peter and Fox, Howard (2004) Predicting response to omalizumab, an anti-IgE antibody, in patients with allergic asthma. Chest, 125, (4), 1378-1386.

Boutsiouki, Paraskevi and Clough, Geraldine F. (2004) Modulation of microvascular function following low-dose exposure to the organophosphorous compound malathion in human skin in vivo. Journal of Applied Physiology, 97, (3), 1091-1097. (doi:10.1152/japplphysiol.00123.2004).

Boutsiouki, Paraskevi, Georgiou, Sophia and Clough, Geraldine F. (2004) Recovery of nitric oxide from acetylcholine-mediated vasodilatation in human skin in vivo. Microcirculation, 11, (3), 249-259. (doi:10.1080/10739680490425958).

Burdge, Graham C. and Postle, Anthony D. (2004) Selective changes to phosphatidylcholine and phosphatidylethanolamine molecular species in the developing fetal guinea pig liver and plasma. Reproduction, Nutrition, Development, 44, (6), 571-582. (doi:10.1051/rnd:2004060).

Cakebread, Julie A., Haitchi, H.-M., Holloway, John W., Powell, Robert M., Keith, Tim, Davies, Donna E. and Holgate, Stephen T. (2004) The role of ADAM33 in the pathogenesis of asthma. Springer Seminars in Immunopathology, 25, (3-4), 361-375. (doi:10.1007/s00281-003-0153-z).

Calder, Virginia L. and Lackie, Peter M. (2004) Basic science and pathophysiology of ocular allergy. Current Allergy and Asthma Reports, 4, (4), 326-331.

Clarke, Ian N., Cutcliffe, Leslie T., Everson, J. Sylvia, Garner, Sarah A., Lambden, Paul R., Pead, Paddy J., Pickett, Mark A., Brentlinger, Karie L. and Fane, Bentley A. (2004) Chlamydiaphage Chp2, a skeleton in the φX174 closet: scaffolding protein and procapsid identification. Journal of Bacteriology, 186, (22), 7571-7574. (doi:10.1128/JB.186.22.7571-7574.2004).

Coles, S.J., Davies, D.B., Hursthouse, M.B., Kilic, A., Mayer, T.A., Shaw, R.A. and Ciftci, G.Y. (2004) Structural investigations of phosphorus-nitrogen compounds. 6. Relationships between molecular parameters in per-X-substituted bridged spermine derivatives and basicity constants ΣαR of substituents. Acta Crystallographica Section B: Structural Crystallography and Crystal Chemistry, 60, (6), 739-747. (doi:10.1107/S0108768104025947).

Cooper, H.L., Cook, I.S., Theaker, J.M., Mallipeddi, R., McGrath, J., Friedmann, P. and Healy, E. (2004) Expression and glycosylation of MUC1 in epidermolysis bullosa-associated and sporadic cutaneous squamous cell carcinomas. The British Journal of Dermatology, 151, (3), 540-545. (doi:10.1111/j.1365-2133.2004.06075.x).

Coward, W.R., Sagara, H., Wilson, S.J., Holgate, S.T. and Church, M.K. (2004) Allergen activates peripheral blood eosinophil nuclear factor-kappaB to generate granulocyte macrophage-colony stimulating factor, tumour necrosis factor-alpha and interleukin-8. Clinical and Experimental Allergy, 34, (7), 1071-1078. (doi:10.1111/j.1365-2222.2004.02003.x).

Cushley, M.J., Tattersfield, A.E. and Holgate, S.T. (2004) Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. British Journal of Clinical Pharmacology, 58, (7), S751-S755. (doi:10.1111/j.1365-2125.2004.02285.x).

DePaulis, Amato, Prevete, Nella, Fiorentino, Isabella, Walls, Andrew F., Curto, Monica, Petraroli, Angelica, Castaldo, Vincenza, Ceppa, Paola, Fiocca, Roberto and Marone, Gianni (2004) Basophils infiltrate human gastric mucosa at sites of Helicobacter pylori infection, and exhibit chemotaxis in response to H. pylori-derived peptide Hp(2-20). Journal of Immunology, 172, (12), 7734-7743.

Dent, Gordon, Hadjicharalambous, Chrystalleni, Yoshikawa, Takahiro, Handy, Rachel L.C., Powell, John, Anderson, Ian K., Louis, Renaud, Davies, Donna E. and Djukanovic, Ratko (2004) Contribution of eotaxin-1 to eosinophil chemotactic activity of moderate and severe asthmatic sputum. American Journal of Respiratory and Critical Care Medicine, 169, (10), 1110-1117. (doi:10.1164/rccm.200306-855OC).

Djukanovic, Ratko, Wilson, SusanJ., Kraft, Monica, Jarjour, Nizar N., Steel, Mark, Chung, K. Fan, Bao, Weibin, Fowler-Taylor, Angel, Matthews, John, Busse, William W., Holgate, Stephen T. and Fahy, John V. (2004) Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. American Journal of Respiratory and Critical Care Medicine, 170, (6), 583-593. (doi:10.1164/rccm.200312-1651OC).

Dorne, J.L., Walton, K. and Renwick, A.G. (2004) Human variability in the renal elimination of foreign compounds and renal excretion-related uncertainty factors for risk assessment. Food and chemical toxicology, 42, (2), 275-298. (doi:10.1016/j.fct.2003.09.002).

Dorne, J.L.C.M., Walton, K. and Renwick, A.G. (2004) Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation). Food and Chemical Toxicology, 42, (3), 397-421. (doi:10.1016/j.fct.2003.10.003).

Dunstan, J.A., Mori, T.A., Barden, A., Beilin, L.J., Holt, P.G., Calder, P.C., Taylor, A.L. and Prescott, S.L. (2004) Effects of n-3 polyunsaturated fatty acid supplementation in pregnancy on maternal and fetal erythrocyte fatty acid composition. European Journal of Clinical Nutrition, 58, (3), 429-437. (doi:10.1038/sj.ejcn.1601825).

Emmans, V.C., Rodway, H.A., Hunt, A.N. and Lillycrop, K.A. (2004) Regulation of cellular processes by PPARγ ligands in neuroblastoma cells is modulated by the level of retinoblastoma protein expression. Biochemical Society Transactions, 32, 840-842.

Fallowfield, Jonathan A. and Iredale, ­John P. (2004) Targeted treatments for cirrhosis. Expert Opinion on Therapeutic Targets, 8, (5), 423-435. (doi:10.1517/14728222.8.5.423).

Faust, S.N ., Woodrow, C.J., Patel, S., Snape, M., Chiodini, P.L., Tudor-Williams, G. and Hermione Lyall, E.G. (2004) Sleeping sickness in brothers in London. The Pediatric Infectious Disease Journal, 23, (9), 879-881. (doi:10.1097/01.inf.0000137587.80399.3b).

Faust, S.N., Welch, S. and Modi, N. (2004) New therapies for treating infections in infants and children. Current paediatrics, 14, (2), 122-130. (doi:10.1016/j.cupe.2003.11.014).

Fleming, John S., Sauret, Veronique, Conway, Joy H. and Martonen, Ted B. (2004) Validation of the conceptual anatomical model of the lung airway. Journal of Aerosol Medicine, 17, (3), 260-269. (doi:10.1089/jam.2004.17.260).

Fowler, Mark I., Weller, Roy O., Heckels, John E. and Christodoulides, Myron (2004) Different meningitis-causing bacteria induce distinct inflammatory responses on interaction with cells of the human meninges. Cellular Microbiology, 6, (6), 555-567. (doi:10.1111/j.1462-5822.2004.00382.x).

Frew, A.J. (2004) Immunotherapy combined with pharmacotherapy. Clinical Allergy and Immunology, 18, 561-566.

Froggatt, Pippa C., Vipond, I. Barry, Ashley, Charles R., Lambden, Paul R., Clarke, Ian N. and Caul, E. Owen (2004) Surveillance of norovirus infection in a study of sporadic childhood gastroenteritis in South West England and South Wales, during one winter season (1999-2000). Journal of Medical Virology, 72, (2), 307-311. ( doi:10.1002/jmv.10569).

Gadola, S., Salzer, U., Schultz, H. and Grimbacher, B. (2004) Adult-onset primary immunodeficiencies. Internist, 45, (8), 912-922. (doi:10.1007/s00108-004-1230-7 ). (PMID:15241502).

Garner, Sarah A., Everson, J. Sylvia, Lambden, Paul R., Fane, Bentley A. and Clarke, Ian N. (2004) Isolation, molecular characterisation and genome sequence of a bacteriophage (Chp3) from Chlamydophila pecorum. Virus Genes, 28, (2), 207-214. (doi:10.1023/B:VIRU.0000016860.53035.f3).

Gjerstorff, Morten, Madsen, Jens, Bendixen, Christian, Holmskov, Uffe and Hansen, Soren (2004) Genomic and molecular characterization of bovine surfactant protein D (SP-D). Molecular Immunology, 41, (4), 369-376. (doi:10.1016/j.molimm.2004.03.005).

Grimfeld, A., Holgate, S.T., Canonica, G.W., Bonini, S., Borres, M.P., Adam, D., CansecoGonzalez, C., Lobaton, P., Patel, P., Szczeklik, A., Danzig, M.R., Roman, I., Bismut, H. and Czarlewski, W. (2004) Prophylactic management of children at risk for recurrent upper respiratory infections: the Preventia I Study. Clinical and Experimental Allergy, 34, (11), 1665-1672. (doi:10.1111/j.1365-2222.2004.02098.x).

Hadjicharalambous, Chrystalleni, Dent, Gordon, May, Richard D., Handy, Rachel L.C., Anderson, Ian K., Davies, Donna E. and Djukanovic, Ratko (2004) Measurement of eotaxin (CCL11) in induced sputum supernatants: validation and detection in asthma. Journal of Allergy and Clinical Immunology, 113, (4), 657-662. (doi:10.1016/j.jaci.2004.01.757).

Hadziyannis, Stephanos J., Sette, Hoel, JrMorgan, Timothy R., Balan, Vijayan, Diago, Moises, Marcellin, Patrick, Ramadori, Giuliano, Bodenheimer, Henry, JrBernstein, David, Rizzetto, Mario, Zeuzem, Stefan, Pockros, Paul J., Lin, Amy and Ackrill, Andrew M. (2004) Peginterferon-α2a and ribavirin combination therapy in chronic hepatitis C. A randomized study of treatment duration and ribavirin dose. Annals of Internal Medicine, 140, (5), 346-355.

Haitchi, H.M. and Holgate, S.T. (2004) New strategies in the treatment and prevention of allergic diseases. Expert Opinion on Investigational Drugs, 13, (2), 107-124.

He, Shaoheng, Aslam, Akhmed, Gaca, Marianna D., He, Yongsong, Buckley, Mark G., Hollenberg, Morley D. and Walls, Andrew F. (2004) Inhibitors of tryptase as mast cell-stabilizing agents in the human airways: effects of tryptase and other agonists of proteinase-activated receptor 2 on histamine release. Journal of Pharmacology and Experimental Therapeutics, 309, (1), 119-126. (doi:10.1124/jpet.103.061291). (PMID:14722328).

Healy, E. (2004) Melanocortin 1 receptor variants, pigmentation, and skin cancer susceptibility. Photodermatology, Photoimmunology & Photomedicine, 20, (6), 283-288. (doi:10.1111/j.1600-0781.2004.00132.x).

Holgate, S.T. (2004) Lessons learnt from the epidemic of asthma. QJM: An International Journal of Medicine, 97, (5), 247-257. (doi:10.1093/qjmed/hch052).

Holgate, S.T., Bousquet, J., Chung, K.F., Bisgaard, H., Pauwels, R., Fabbri, L., Rabe, K., Doherty, M., Snell, N.J.C., Cuss, F., D'Amato, M. and Reginster, J.Y. Group for the Respect of Ethics and Excellence in Science (GREES): Asthma section (2004) Summary of recommendations for the design of clinical trials and the registration of drugs used in the treatment of asthma. Respiratory Medicine, 98, (6), 479-487. (doi:10.1016/j.rmed.2003.12.005).

Holgate, S.T., Chuchalin, A.G., Hebert, J., Lotvall, J., Persson, G.B., Chung, K.F., Bousquet, J., Kerstjens, H.A., Fox, H., Thirlwell, J. and Cioppa, G.D. (2004) Efficacy and safety of a recombinant anti-immunoglobulin E antibody (omalizumab) in severe allergic asthma. Clinical and Experimental Allergy, 34, (4), 632-638. (doi:10.1111/j.1365-2222.2004.1916.x).

Holgate, Stephen T. (2004) Cytokine and anti-cytokine therapy for the treatment of asthma and allergic disease. Cytokine, 28, (4-5), 152-157. (doi:10.1016/j.cyto.2004.07.010).

Holgate, Stephen T. (2004) The epidemic of asthma and allergy. Journal of the Royal Society of Medicine, 97, (3), 103-110.

Holgate, Stephen T. (2004) Genetic common ground between allergic and autoimmune disease: the role of cytotoxic T-lymphocyte antigen 4. Journal of Allergy and Clinical Immunology, 114, (2), 277-279. (doi:10.1016/j.jaci.2004.05.052).

Holgate, Stephen T. (2004) Pharmacogenetics: the new science of personalizing treatment. Current Opinion in Allergy and Clinical Immunology, 4, (1), 37-38.

Holgate, Stephen T., Davies, Donna E., Rorke, Steuart, Cakebread, Julie, Murphy, Gillian, Powell, Robert M. and Holloway, John W. (2004) ADAM 33 and its association with airway remodeling and hyperresponsiveness in asthma. Clinical Reviews in Allergy & Immunology, 27, (1), 23-34.

Holgate, Stephen T., Holloway, John, Wilson, Susan, Bucchieri, Fabio, Puddicombe, Sarah and Davies, Donna E. (2004) Epithelial-mesenchymal communication in the pathogenesis of chronic asthma. Proceedings of the American Thoracic Society, 1, (2), 93-98.

Holloway, J.W. and Holgate, S.T. (2004) Genetics. Chemical Immunology and Allergy, 84, 1-35. (doi:10.1159/000081548).

Holloway, John W., Keith, Tim P., Davies, Donna E., Powell, Robert, Haitchi, Hans-Michael and Holgate, Stephen T. (2004) The discovery and role of ADAM33, a new candidate gene for asthma. Expert Reviews in Molecular Medicine, 6, (17), 1-12. (doi:10.1017/S1462399404007963).

Holt, Patrick, Naspitz, Charles and Warner, John O. (2004) Early immunological influences. Prevention of Allergy and Allergic Asthma: World Allergy Organization Project Report and Guidelines, 84, 102-127. (doi:10.1159/000081440).

Howarth, Peter H., Knox, Alan J., Amrani, Yassine, Tliba, Omar, Panettieri, Reynold A. and Johnson, Malcolm (2004) Synthetic responses in airway smooth muscle. Journal of Allergy and Clinical Immunology, 114, (2 Supplement 1), S32-S50. (doi:10.1016/j.jaci.2004.04.041).

Humphries, Holly E., Williams, Jeanette N., Christodoulides, Myron and Heckels, John E. (2004) Recombinant meningococcal PorA protein, expressed using a vector system with potential for human vaccination, induces a bactericidal immune response. Vaccine, 22, (11-12), 1564-1569. ( doi:10.1016/j.vaccine.2003.09.042).

Hunt, A.N., Alb, J.G., Koster, G., Postle, A.D. and Bankaitis, V.A. (2004) Use of mass spectrometry-based lipidomics to probe PITPα (phosphatidylinositol transfer protein α) function inside the nuclei of PITPα+/+ and PITPα-/- cells. Biochemical Society Transactions, 32, (6), 1063-1065. (doi:10.1042/BST0321063).

Hunt, A.N., Fenn, H.C., Clark, G.T., Wright, M.M., Postle, A.D. and McMaster, C.R. (2004) Lipidomic analysis of the molecular specificity of a cholinephosphotransferase in situ. Biochemical Society Transactions, 32, (Part 6), 1060-1062.

Hunt, Alan N. and Postle, Anthony D. (2004) Phosphatidylcholine biosynthesis inside the nucleus: is it involved in regulating cell proliferation? Advances in Enzyme Regulation, 44, (1), 173-186. (doi:10.1016/j.advenzreg.2003.11.018).

Hunt, Alan N., Skippen, Alison J., Koster, Grielof, Postle, Anthony D. and Cockcroft, Shamshad (2004) Acyl chain-based molecular selectivity for HL60 cellular phosphatidylinositol and of phosphatidylcholine by phosphatidylinositol transfer protein α. Biochimica et Biophysica Acta: Molecular and Cell Biology of Lipids, 1686, (1-2), 50-60. (doi:10.1016/j.bbalip.2004.08.003).

Issa, Razao, Zhou, Xiaoying, Constandinou, Christothea, Fallowfield, Jonathan, Millward-Sadler, Harry, Gaca, Marianna D.A., Sands, Emma, Suliman, Ibnauf, Trim, Nathan, Knorr, Andreas, Arthur, Michael J.P., Benyon, R. Christopher and Iredale, John P. (2004) Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking. Gastroenterology, 126, (7), 1795-1808. (doi:10.1053/j.gastro.2004.03.009).

Iwanaga, T., McEuen, A., Walls, A.F., Clough, J.B., Keith, T.P., Rorke, S., Barton, S.J., Holgate, S.T. and Holloway, J.W. (2004) Polymorphism of the mast cell chymase gene (CMA1) promoter region: lack of association with asthma but association with serum total immunoglobulin E levels in adult atopic dermatitis. Clinical and Experimental Allergy, 34, (7), 1037-1042. (doi:10.1111/j.1365-2222.2004.02000.x).

Johansson, S.G.O., Bieber, T., Dahl, R., Friedmann, P.S., Lanier, B.Q., Lockey, R.F., Motala, C., OrtegaMartell, J.A., Platts-Mills, T.A., Ring, J., Thien, F., VanCauwenberge, P. and Williams, H.C. (2004) Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003. Journal of Allergy and Clinical Immunology, 113, (5), 832-836. (doi:10.1016/j.jaci.2003.12.591).

Jordens, J. Zoe, Williams, Jeannette N., Jones, Graeme R., Christodoulides, Myron and Heckels, John E. (2004) Development of immunity to serogroup B meningococci during carriage of Neisseria meningitidis in a cohort of university students. Infection and Immunity, 72, (11), 6503-6510. (doi:10.1128/IAI.72.11.6503-6510.2004).

Kapoor, S., Roberts, G., Bynoe, Y., Gaughan, M., Habibi, P. and Lack, G. (2004) Influence of a multidisciplinary paediatric allergy clinic on parental knowledge and rate of subsequent allergic reactions. Allergy, 59, (2), 185-191. (doi:10.1046/j.1398-9995.2003.00365.x).

Khakoo, Salim I., Thio, Chloe L., Martin, Maureen P., Brooks, Collin R., Gao, Xiaojiang, Astemborski, Jacquie, Cheng, Jie, Goedert, James J., Vlahov, David, Hilgartner, Margaret, Cox, Steven, Little, Ann-Margeret, Alexander, Graeme J., Cramp, Matthew E., O'Brien, Stephen J., Rosenberg, William M., Thomas, David L. and Carrington, Mary (2004) HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection. Science, 305, (5685), 872-874. (doi:10.1126/science.1097670).

Kyriakou, Theodosios, Hodgkinson, Conrad, Pontefract, David E., Iyengar, Srikanth, Howell, W.Martin, Wong, Yuk-ki, Eriksson, Per and Ye, Shu (2004) Genotypic effect of the -565C>T polymorphism in the ABCA1 gene promoter on ABCA1 expression and severity of atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 25, (2), 418-423. (doi:10.1161/01.ATV.0000149379.72018.20).

Lee, J.H., Park, H.S., Park, S.W., Jang, A.S., Uh, S.T., Rhim, T., Park, C.S., Hong, S.J., Holgate, S.T., Holloway, J.W. and Shin, H.D. (2004) ADAM33 polymorphism: association with bronchial hyper-responsiveness in Korean asthmatics. Clinical and Experimental Allergy, 34, (6), 860-865. (doi:10.1111/j.1365-2222.2004.01977.x).

Li, Chris K.F., Pender, Sylvia L.F., Pickard, Karen M., Chance, Victoria, Holloway, Judith A., Huett, Alan, Gonçalves, Nathalie S., Mudgett, John S., Dougan, Gordon, Frankel, Gad and MacDonald, Thomas T. (2004) Impaired immunity to intestinal bacterial infection in stromelysin-1 (matrix metalloproteinase-3)-deficient mice. Journal of Immunology, 173, (8), 5171-5179.

Lucas, J., Lewis, S., Grimshaw, K., Warner, J. and Hourihane, J. (2004) Use of the FAO/WHO decision tree to identify allergenicity in a non-GM novel food. Clinical and Experimental Allergy, 34, (11), 1811-1811. (doi:10.1111/j.1365-2222.2004.t01-1-02086.x).

Lucas, J.S.A., Grimshaw, K.E.C., Collins, K., Warner, J.O. and Hourihane, O'B. (2004) Kiwi fruit is a significant allergen and is associated with differing patterns of reactivity in children and adults. Clinical and Experimental Allergy, 34, (7), 1115-1121. (doi:10.1111/j.1365-2222.2004.01982.x).

Lucas, Jane S., Inskip, Hazel M., Godfrey, Keith M., Foreman, Claire T., Warner, John O., Gregson, Rachael K. and Clough, Joanne B. (2004) Small size at birth and greater postnatal weight gain: relationships to diminished infant lung function. American Journal of Respiratory and Critical Care Medicine, 170, (5), 534-540. (doi:10.1164/rccm.200311-1583OC).

MacDonald, Andrew, Crowder, Katherine, Street, Andrew, McCormick, Christopher and Harris, Mark (2004) The hepatitis C virus NS5A protein binds to members of the Src family of tyrosine kinases and regulates kinase activity. The Journal of General Virology, 85, (3), 721-729. (doi:10.1099/vir.0.19691-0).

MacDonald, Thomas T. and Pender, Sylvia L.F. (2004) Mechanisms of tissue injury. In, Sartor, R. Balfour and Sandborn, William J. (eds.) Inflammatory Bowel Diseases. Sixth Edition. United States, US, Saunders, 163-178.

Mansur, A.H., Bishop, D.T., Holgate, S.T., Markham, A.F. and Morrison, J.F.J. (2004) Linkage/association study of a locus modulating total serum IgE on chromosome 14q13-24 in families with asthma. Thorax, 59, (10), 876-882.

Markel, Gal, Mussaffi, Huda, Ling, Khoon-Lin, Salio, Mariolina, Gadola, Stephan, Steuer, Guy, Blau, Hannah, Achdout, Hagit, de Miguel, María, Gonen-Gross, Tsufit, Hanna, Jacob, Arnon, Tal I., Qimron, Udi, Volovitz, Ilan, Eisenbach, Lea, Blumberg, Richard S., Porgador, Angel, Cerundolo, Vincenzo and Mandelboim, Ofer (2004) The mechanisms controlling NK cell autoreactivity in TAP2-deficient patients. Blood, 103, (5), 1770-1778. (doi:10.1182/blood-2003-06-2114). (PMID:14604968).

McArdle, Frank, Rhodes, Lesley E., Parslew, Richard A., Close, Graeme L., Jack, Catherine I. A., Friedmann, Peter S. and Jackson, Malcolm J. (2004) Effects of oral vitamin E and β-carotene supplementation on ultraviolet radiation-induced oxidative stress in human skin. American Journal of Clinical Nutrition, 80, (5), 1270-1275.

McCormick, C.J., Challinor, L., Macdonald, A., Rowlands, D.J. and Harris, M. (2004) Introduction of replication-competent hepatitis C virus transcripts using a tetracycline-regulable baculovirus delivery system. Journal of General Virology, 85, (2), 429-439. (doi:10.1099/vir.0.19676-0).

McGill, James I. (2004) A review of the use of olopatadine in allergic conjunctivitis. International Ophthalmology, 25, (3), 171-179. (doi:10.1007/s10792-004-1818-x).

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Palaniyar, Nades, Nadesalingam, Jeya, Clark, Howard, Shih, Michael J., Dodds, Alister W. and Reid, Kenneth B.M. (2004) Nucleic acid is a novel ligand for innate, immune pattern recognition collectins surfactant proteins A and D and mannose-binding lectin. Journal of Biological Chemistry, 279, (31), 32728-32736. (doi:10.1074/jbc.M403763200).

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Palmer, Roy A. and Friedmann, Peter S. (2004) Ultraviolet radiation causes less immunosuppression in patients with polymorphic light eruption than in controls. The Journal of Investigative Dermatology, 122, (2), 291-294. (doi:10.1046/j.0022-202X.2004.22213.x).

Park, Hae-Sim, Kim, Seung-Hyun, Sampson, Anthony P., Lee, Kyung-Wha and Park, Choon-Sik (2004) Letter to the editor. The HLA-DPB1*0301 marker might predict the requirement for leukotriene receptor antagonist in patients with aspirin-intolerant asthma. Journal of Allergy and Clinical Immunology, 114, (3), 688-689. (doi:10.1016/j.jaci.2004.05.051).

Pender, S.L.F., Croucher, P.J., Mascheretti, S., Prothero, J.D., Fisher, S.A., MacDonald, T.T., Schreiber, S. and Ye, S. (2004) Transmission disequilibrium test of stromelysin-1 gene variation in relation to Crohn's disease. Journal of Medical Genetics, 41, (9), e112. (doi:10.1136/jmg.2004.023572).

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Postle, A.D., Dombrowsky, H., Clarke, H., Pynn, C.J., Koster, G. and Hunt, A.N. (2004) Mass spectroscopic analysis of phosphatidylinositol synthesis using 6-deuteriated-myo-inositol: comparison of the molecular specificities and acyl remodelling mechanisms in mouse tissues and cultured cells. Biochemical Society Transactions, 32, (6), 1057-1059.

Postle, Anthony D., Madden, Jackie, Clark, Graeme T. and Wright, Sarah M. (2004) Electrospray ionisation mass spectrometry analysis of differential turnover of phosphatidylcholine by human blood leukocytes. Physical Chemistry Chemical Physics, 6, 1018-1021. (doi:10.1039/b312196h).

Pourazar, Jamshid, Frew, Anthony J., Blomberg, Anders, Helleday, Ragnberth, Kelly, Frank J., Wilson, Susan and Sandström, Thomas (2004) Diesel exhaust exposure enhances the expression of IL-13 in the bronchial epithelium of healthy subjects. Respiratory Medicine, 98, (9), 821-825. (doi:10.1016/j.rmed.2004.02.025). (PMID:15338792).

Powe, D.G., Huskisson, R.S., Carney, A.S., Jenkins, D., McEuen, A.R., Walls, A.F. and Jones, N.S. (2004) Mucosal T-cell phenotypes in persistent atopic and nonatopic rhinitis show an association with mast cells. Allergy, 59, (2), 204-212. (doi:10.1046/j.1398-9995.2003.00315.x).

Powell, Robert M., Wicks, James, Holloway, John W., Holgate, Stephen T. and Davies, Donna E. (2004) The splicing and fate of ADAM33 transcripts in primary human airways fibroblasts. American Journal of Respiratory Cell and Molecular Biology, 31, (1), 13-21. (doi:10.1165/rcmb.2003-0330OC).

Renwick, A.G. (2004) Risk characterisation of chemicals in food. Toxicology Letters, 149, (1-3), 163-176. (doi:10.1016/j.toxlet.2003.12.063).

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Roberts, G., Hurley, C., Bush, A. and Lack, G. (2004) Longitudinal study of grass pollen exposure, symptoms, and exhaled nitric oxide in childhood seasonal allergic asthma. Thorax, 59, (9), 752-756.

Rosenberg, William M.C., Voelker, Michael, Thiel, Robert, Becka, Michael, Burt, Alastair, Schuppan, Detlef, Hubscher, Stefan, Roskams, Tania, Pinzani, Massimo and Arthur, Michael J.P. European Liver Fibrosis Group (2004) Serum markers detect the presence of liver fibrosis: a cohort study. Gastroenterology, 127, (6), 1704-1713. (doi:10.1053/j.gastro.2004.08.052).

Salib, Rami J., Kumar, Sanjiv, Wilson, Susan J. and Howarth, Peter H. (2004) Nasal mucosal immunoexpression of the mast cell chemoattractants TGF-β, eotaxin, and stem cell factor and their receptors in allergic rhinitis. Journal of Allergy and Clinical Immunology, 114, (4), 799-806. (doi:10.1016/j.jaci.2004.07.010).

Salmela, M.T., Pender, S.L.F., Karjalainen-Lindsberg, M.L., Puolakkainen, P., MacDonald, T.T. and Saarialho-Kere, U. (2004) Collagenase-1 (MMP-1), matrilysin-1 (MMP-7), and stromelysin-2 (MMP-10) are expressed by migrating enterocytes during intestinal wound healing. Scandinavian Journal of Gastroenterology, 39, (11), 1095-1104. (doi:10.1080/00365520410003470).

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Shaw, T.J., Wakely, S.L., Peebles, C.R., Mehta, R.L., Turner, J.M., Wilson, S.J. and Howarth, P.H. (2004) Endobronchial ultrasound to assess airway wall thickening: validation in vitro and in vivo. European Respiratory Journal, 23, (6), 813-817.

Shek, Fanny W. and Benyon, R. Christopher (2004) How can transforming growth factor beta be targeted usefully to combat liver fibrosis. European Journal of Gastroenterology and Hepatology, 16, (2), 123-126.

Shute, J.K., Solic, N., Shimizu, J., McConnell, W., Redington, A.E. and Howarth, P.H. (2004) Epithelial expression and release of FGF-2 from heparan sulphate binding sites in bronchial tissue in asthma. Thorax, 59, (7), 557-562. (doi:10.1136/thx.2002.002626).

Smith, Helen, White, Peter, Annila, Ilkka, Poole, Jason, Andre, Claude and Frew, Anthony (2004) Randomized controlled trial of high-dose sublingual immunotherapy to treat seasonal allergic rhinitis. Journal of Allergy and Clinical Immunology, 114, (4), 831-837. (doi:10.1016/j.jaci.2004.06.058).

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Willis, E.F., Clough, G.F. and Church, M.K. (2004) Investigation into the mechanisms by which nedocromil sodium, frusemide and bumetanide inhibit the histamine-induced itch and flare response in human skin in vivo. Clinical and Experimental Allergy, 34, (3), 450-455. (doi:10.1111/j.1365-2222.2004.01898.x).

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