The cooling effect of liquid flow on the focussed ultrasound-induced heating in a simulated foetal brain
The cooling effect of liquid flow on the focussed ultrasound-induced heating in a simulated foetal brain
There is a need to investigate the thermal effects of diagnostic ultrasound (US) to assist the development of appropriate safety guidelines for obstetric use. The cooling effect of a single liquid flow channel was measured in a model of human foetal brain and skull bone heated by a focussed beam of simulated pulsed spectral Doppler US. Insonation conditions were 5.7 s pulses, repeated at 8 kHz from a focussed transducer operating with a centre frequency of 3.5 MHz, producing a beam of ?6 dB diameter of 3.1 mm at the focus and power outputs of up to 255 ± 5 mW. Brain perfusion was simulated by allowing distilled water to flow at various rates in a 2 mm diameter wall-less channel in the brain soft tissue phantom material. This study established that the cooling effect of the flowing water; 1. was independent of the acoustic source power, 2. was more effective close to the flow channel, for example, there was a marked cooling at a distance of 1 mm and negligible cooling at a distance of 3 mm from the channel; and 3. initially increased at low flow rates, but further increase above normal perfusion had very little effect.
pulsed ultrasound, phantom, foetus, liquid flow, bone heating, hyperthermia, focussed ultrasound beam
1193-1204
Vella, G.J.
831f4545-9172-482d-a838-e9145773dae2
Humphrey, V.F.
23c9bd0c-7870-428f-b0dd-5ff158d22590
Duck, F.A.
a1178433-533c-4547-8710-3413f044a119
Barnett, S.B.
1e755f4b-00b6-4f9b-8e91-34fa27792ca0
2003
Vella, G.J.
831f4545-9172-482d-a838-e9145773dae2
Humphrey, V.F.
23c9bd0c-7870-428f-b0dd-5ff158d22590
Duck, F.A.
a1178433-533c-4547-8710-3413f044a119
Barnett, S.B.
1e755f4b-00b6-4f9b-8e91-34fa27792ca0
Vella, G.J., Humphrey, V.F., Duck, F.A. and Barnett, S.B.
(2003)
The cooling effect of liquid flow on the focussed ultrasound-induced heating in a simulated foetal brain.
Ultrasound in Medicine & Biology, 29 (8), .
(doi:10.1016/S0301-5629(03)00064-4).
Abstract
There is a need to investigate the thermal effects of diagnostic ultrasound (US) to assist the development of appropriate safety guidelines for obstetric use. The cooling effect of a single liquid flow channel was measured in a model of human foetal brain and skull bone heated by a focussed beam of simulated pulsed spectral Doppler US. Insonation conditions were 5.7 s pulses, repeated at 8 kHz from a focussed transducer operating with a centre frequency of 3.5 MHz, producing a beam of ?6 dB diameter of 3.1 mm at the focus and power outputs of up to 255 ± 5 mW. Brain perfusion was simulated by allowing distilled water to flow at various rates in a 2 mm diameter wall-less channel in the brain soft tissue phantom material. This study established that the cooling effect of the flowing water; 1. was independent of the acoustic source power, 2. was more effective close to the flow channel, for example, there was a marked cooling at a distance of 1 mm and negligible cooling at a distance of 3 mm from the channel; and 3. initially increased at low flow rates, but further increase above normal perfusion had very little effect.
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Published date: 2003
Keywords:
pulsed ultrasound, phantom, foetus, liquid flow, bone heating, hyperthermia, focussed ultrasound beam
Identifiers
Local EPrints ID: 10337
URI: http://eprints.soton.ac.uk/id/eprint/10337
ISSN: 0301-5629
PURE UUID: 49b4164c-cb2b-4816-bb0c-2065962669b5
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Date deposited: 19 May 2005
Last modified: 16 Mar 2024 03:34
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Author:
G.J. Vella
Author:
F.A. Duck
Author:
S.B. Barnett
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